Research theme for competitive and other funds (15):
2023 - 2028 冬眠生物学2.0 総括班
2022 - 2026 Novel Strategy to Prevent Skeletal Muscle Atrophy Based on "Muscle Atrophy Resistance" in Hibernating Animals
2020 - 2023 Mammalian hibernation biology ~ survival strategies via hypometabolism and hypothermia
2020 - 2023 哺乳類の低代謝・低体温による生存戦略の統合的理解
2020 - 2023 冬眠発動の分子機構:深冬眠実行の分子基盤と飢餓性休眠との共通性の解明
2019 - 2022 Investigation of skeletal muscle remodeling for hibernation in a mammalian hibernator Syrian hamster
2018 - 2021 Investigation of mechanisms inducing spontaneous hypothermia in a mammalian hibernator
2016 - 2019 Investigation of mechanisms enabling mammalian hibernation
2016 - 2019 Live cell imaging of regulated necrosis
2015 - 2019 Establishment of international research community on cell death
2014 - 2019 Homeostatic regulation by various type of cell death
2014 - 2019 Visualization and significance of various types of regulated cell death in vivo
2016 - 2018 An attempt to generate transgenic hamsters for hibernation research
2012 - 2014 マウス初期胚発生過程で細胞死が周辺細胞動態に与える影響の解明
2011 - 2012 Approach to reveal dynamics of caspase activation in maintainingbrain homeostasis
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Papers (46):
Reo Otsuka, Yutaro Shimoyama, Satoshi Nakagawa, Yoshifumi Yamaguchi. Tools of Hibernation Measurement and Interpretation (TOHMIN) for quantifying various values from body temperature fluctuation during hibernation. 2024
Masamitsu Sone, Nonoka Mitsuhashi, Yuki Sugiura, Yuta Matsuoka, Rae Maeda, Akari Yamauchi, Ryoto Okahashi, Junpei Yamashita, Kanako Sone, Sachiyo Enju, et al. Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator. Cell death & disease. 2024. 15. 9. 685-685
Shingo Gibo, Yoshifumi Yamaguchi, Elena O. Gracheva, Sviatoslav N. Bagriantsev, Isao T. Tokuda, Gen Kurosawa. Frequency-modulated timer regulates torpor-arousal cycles during hibernation in distinct small mammalian hibernators. npj Biological Timing and Sleep. 2024
Masamitsu Sone, Junpei Yamashita, Shuji Shigenobu, Yoshifumi Yamaguchi. Slow decrease in temperature produces readthrough transcripts in mammalian hibernation. Biochemical and Biophysical Research Communications. 2024. 709. 149837-149837
Taiga Ishimoto, Hideyuki Kosumi, Ken Natsuga, Yoshifumi Yamaguchi. Nail growth arrest under low body temperature during hibernation. The Journal of Physiological Sciences. 2024
2018/01 - 現在 Hokkaido University Institute of Low Temperature Science
2016/06 - 2017/12 The University of Tokyo Graduate School of Pharmaceutical Sciences
2007 - 2016/06 The University of Tokyo Graduate School of Pharmaceutical Sciences
2006 - 東京大学 薬学研究科(研究院) 助手
Association Membership(s) (7):
日本筋学会
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, 日本 Cell Death学会
, THE JAPANESE BIOCHEMICAL SOCIETY
, THE PHYSIOLOGICAL SOCIETY OF JAPAN
, 日本神経科学学会
, 日本発生生物学会