Noda Makoto

Research field (1)： Cell biology

Research keywords (12)： cancer invasion and metastasis , extracellular matrix , brain development , Nedd genes , Rap1/Krev-1 , RAS , septins , angiogenesis , signaling , tumor suppressor genes , MMP , RECK

Research theme for competitive and other funds (34)：

2014 - 2017 The roles of RECK tumor suppressor protein in angiogenesis
2010 - 2016 Generation of Neural Diversity and Neocortex
2010 - 2015 Regulation of pericellular proteolysis and neural development
2004 - 2010 Molecular Basis of the Structure and Function of the Brain
2005 - 2009 Elucidating the role of extracellular matrix remodeling on the fate and behavior of neuron

2004 - 2009 Roles and Regulatory Mechanisms of Extracellular Matrix Remodeling in vivo

2003 - 2005 野生型N-ras遺伝子の組織特異的がん抑制効果とその機構

2003 - 2004 Expression of a Novel MMP Regulator, RECK, and its Clinical Significance in Lung Cancer.

2002 - 2004 significance of septin in the formation of inclusion bodies in neurodegenerative disorders.

2000 - 2004 神経突起伸長に関与する分子の探索と機能解析

1999 - 2004 神経回路の成熟と特異的機能発現のメカニズム

2001 - 2003 Studies on the roles of the membrane-associated matrix metalloproteinase regulator BECK in angiogenesis

1999 - 2001 Screening for signal-responsive genes by an enhancer-trap vector and their application

1998 - 2001 細胞形態制御における細胞質骨格蛋白セプチンの機能解析

1998 - 2000 Nove| strategies for cancer treatment with tumor-specific gene therapy and radiotherapy

1999 - 1999 転移抑制遺伝子RECKの機能とがん遺伝子による発現抑制機構

1998 - 1998 フラット・リバージョン誘導遺伝子RECKによるがん転移抑制機構

1995 - 1998 Search for gcncs rcgulating acuronal plasticity

1995 - 1998 Molecular mechanism of synaptic plasticity

1994 - 1994 神経可塑性の分子機構に関する総合研究

1992 - 1994 がん抑制遺伝子の発現クローニングと機能解析

1992 - 1993 がん抑制遺伝子の発現クローニングと機能解析

1992 - 1992 がん抑制遺伝子の発現クローニングと機能解析

1991 - 1991 がん抑制に関与する遺伝子群の研究

1991 - 1991 細胞分化のプログラミングと癌遺伝子

1989 - 1991 細胞増殖シグナルの発現・伝達とその制御

1990 - 1990 レトロウイルスを利用した癌関連遺伝子の探索とその発現・機能の解析

1989 - 1990 細胞分化のプログラミングと癌遺伝子

1988 - 1990 Cooperation and Information Exchange with European Countries

1989 - 1989 細胞増殖シグナルの伝達とその制御

1989 - 1989 レトロウイルスを利用した癌関連遺伝子の探索とその発現・機能の解析

1989 - 1989 細胞分化のプログラミングと癌遺伝子

1988 - 1988 レトロウイルスを利用した癌関連遺伝子の探索とその発現・機能の解析

1986 - 1986 癌遺伝子産物の発現に関与する細胞因子

Show all

Papers (163)：

Tomoko Matsuzaki, Joe Inoue, Nagahiro Minato, Makoto Noda. Non-cell-autonomous suppression of tumor growth by RECK in immunocompetent mice. Journal of cellular physiology. 2024. e31396
Tomonori Masuda, Akihisa Fukuda, Go Yamakawa, Mayuki Omatsu, Mio Namikawa, Makoto Sono, Yuichi Fukunaga, Munemasa Nagao, Osamu Araki, Takaaki Yoshikawa, et al. Pancreatic RECK inactivation promotes cancer formation, epithelial-mesenchymal transition, and metastasis. The Journal of clinical investigation. 2023. 133. 18
Yoko Yoshida, Kanako Yuki, Shingo Dan, Kanami Yamazaki, Makoto Noda. Suppression of tumor metastasis by a RECK-activating small molecule. Scientific Reports. 2022. 12. 1. 2319-2319
Tomoko Matsuzaki, Douglas R Keene, Emi Nishimoto, Makoto Noda. Reversion-inducing cysteine-rich protein with Kazal motifs and MT1-MMP promote the formation of robust fibrillin fibers. Journal of Cellular Physiology. 2021. 236. 3. 1980-1995
Shuichiro Ogawa, Tomoko Matsuzaki, Makoto Noda. Abundant expression of the membrane-anchored protease-regulator RECK in the anterior pituitary gland and its implication in the growth hormone/insulin-like growth factor 1 axis in mice. Molecular and Cellular Endocrinology. 2020. 508. 110790-110790

ｍore...

MISC (28)：

Yukio Imamura, Huan Wang, Makoto Noda. A protective role of the ECM-regulator Reck in the neuromuscular junctions after peripheral nerve injury. NEUROSCIENCE RESEARCH. 2010. 68. E261-E261
Yukio Imamura, Huan Wang, Makoto Noda. A role of the ECM-remodeling regulator RECK in the neuro-muscular junction. NEUROSCIENCE RESEARCH. 2009. 65. S180-S180
Huan Wang, Yukio Imamura, Makoto Noda. The membrane-anchored regulator RECK is important for the recovery of brain functions after transient cerebral ischemia. NEUROSCIENCE RESEARCH. 2009. 65. S123-S123
Noda M. [Roles of an extracellular matrix regulator RECK in mouse development]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme. 2008. 53. 4. 324-330
Yukio Imamura, Ediriweera P. S. Chandana, Makoto Noda. Role of the membrane-bound matrix metalloprotease regulator RECK in the mouse brain following transient ischemia. NEUROSCIENCE RESEARCH. 2008. 61. S134-S134

ｍore...

Patents (1)：

SCREENING METHOD FOR ANTICANCER DRUGS

Books (12)：

がんのすべてがわかる本
学研パブリッシング,学研マーケティング (発売) 2012 ISBN:9784054051867
医学細胞生物学
東京化学同人 2009
分子生物学
東京化学同人 2009 ISBN:9784807906635
神経回路の機能発現のメカニズム
共立出版 2004 ISBN:4320056248
知っておきたい分子生物学
岩波書店 2003 ISBN:4000068636

ｍore...

Lectures and oral presentations (2)：

Signaling pathways affecting, and affected by, the tumor metastasis suppressor RECK
(The 77th Annual Meeting of the Japanese Cancer Association 2018)
悪性転換抑制遺伝子の探索と応用
(第17回日本がん分子標的治療学会学術集会 2013)

Professional career (1)：

Ph. D. (Keio University)

Work history (1)：

2018/04 - 2020/09 Kyoto University, Vice-President

Awards (3)：

2007/12 - Sagawa Foundation for Promotion of Cancer Research Special Research Grant Award Characterization of ancer-associated genes idenfified based on their bio-activities
1992/02 - Princess Takamatsu Cancer Research Fund Princess Takamatsu Cancer Research Fund Prizes New Approaches to Studies on Tumor-suppressor Genes in Cancers
1989/10 - Japanese Cancer Association Young Investigator Awards Studies on the Krev-1 gene

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page