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J-GLOBAL ID:201101006998219668   Update date: Feb. 12, 2025

Matsuda Noriyuki

マツダ ノリユキ | Matsuda Noriyuki
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Affiliation and department:
Homepage URL  (1): https://nrid.nii.ac.jp/nrid/1000010332272/
Research field  (1): Functional biochemistry
Research keywords  (7): Mitochondria ,  ユビキチン ,  パーキンソン病 ,  PINK1 ,  RING finger motif ,  Parkin ,  DJ-1
Research theme for competitive and other funds  (12):
  • 2019 - 2024 多様なマイトファジーの分子機構と生理的意義の解明
  • 2018 - 2021 Detoxification of aldehyde-conjugation as a new mechanism for preventing onset of Parkinson's disease
  • 2015 - 2017 翻訳後修飾因子の翻訳後修飾:リン酸化ユビキチンの細胞内機能の解析
  • 2014 - 2017 Identification and functional analysis of substrates of disease-associated protein kinases using multiple phosphoproteomic technologies
  • 2014 - 2016 PINK1の作動機構解明からミトコンドリアホメオスタシスと神経変性の核心に迫る
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Papers (71):
  • Fumika Koyano, Noriyuki Matsuda. Quality control of ABCD3 by the VCP-FAF2 complex suppresses excessive pexophagy. Autophagy. 2025
  • Fumika Koyano, Koji Yamano, Tomoyuki Hoshina, Hidetaka Kosako, Yukio Fujiki, Keiji Tanaka, Noriyuki Matsuda. AAA+ ATPase chaperone p97/VCPFAF2 governs basal pexophagy. Nature Communications. 2024
  • Endo R, Kinefuchi H, Sawada M, Kikuchi R, Kojima W, Matsuda N, Yamano K. TBK1 adaptor AZI2/NAP1 regulates NDP52-driven mitochondrial autophagy. The Journal of biological chemistry. 2024
  • Aiko Watanabe, Fumika Koyano, Kenichiro Imai, Yohei Hizukuri, Shizuka Ogiwara, Tomoya Ito, Jun Miyamoto, Chihiro Shibuya, Mayumi Kimura, Kazuya Toriumi, et al. The origin of esterase activity of Parkinson's disease causative factor DJ-1 implied by evolutionary trace analysis of its prokaryotic homolog HchA. The Journal of biological chemistry. 2024. 107476-107476
  • Koji Yamano, Momoha Sawada, Reika Kikuchi, Kafu Nagataki, Waka Kojima, Ryu Endo, Hiroki Kinefuchi, Atsushi Sugihara, Tomoshige Fujino, Aiko Watanabe, et al. Optineurin provides a mitophagy contact site for TBK1 activation. The EMBO Journal. 2024. 43. 5. 754-779
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MISC (63):
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Professional career (1):
  • 理学博士 (東京大学)
Work history (5):
  • 2022/01 - 現在 Tokyo Medical and Dental University Medical Research Institute
  • 2015/04 - 2021/12 公益財団法人 東京都医学総合研究所 ユビキチンプロジェクト プロジェクトリーダー
  • 2011/06 - 2015/03 公益財団法人 東京都医学総合研究所 主席研究員および副参事研究員
  • 2008/06 - 2011/05 (財)東京都医学研究機構 東京都臨床医学総合研究所 主任研究員
  • 2007/04 - 2008/05 RIKEN
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