Rchr
J-GLOBAL ID:201101012696507800
Update date: Mar. 14, 2025 KAWAAI Katsuhiro
カワアイ カツヒロ | KAWAAI Katsuhiro
Affiliation and department: Homepage URL (1): https://nrid.nii.ac.jp/nrid/1000000553653/ Research field (3):
Molecular biology
, Biomaterials
, Neuroscience - general
Research keywords (1):
包括脳ネットワーク
Research theme for competitive and other funds (15): - 2022 - 2025 Elucidation of the mechanisms for bone destruction in chordoma.
- 2021 - 2025 Understanding the cellular basis of left-right symmetry in the skeleton
- 2024 - 2025 左右対称性の骨格が形成される細胞機構の理解に向けて
- 2019 - 2022 骨芽細胞動態解析による軟骨原基を起点とした骨形成過程の解明と応用
- 2020 - 2021 骨化軟骨を模倣したバイオミメティクスコート材の開発および骨芽細胞動態解析による新規評価法の確立
- 2019 - 2020 骨化軟骨を模倣したバイオミメティクスコート材の開発および骨芽細胞動態解析による新規評価法の確立
- 2019 - 2020 脊索腫における骨破壊機序の解明
- 2018 - 2019 骨化軟骨を模倣したバイオミメティクスコート材の開発および骨芽細胞動態解析による新規評価法の確立
- 2017 - 2019 メチオニン代謝系制御因子を中心とした神経管閉鎖不全症の発 症機序の解明
- 2016 - 2019 Roles of the pH regulation through HCO3- transporters in perisynaptic astrocytes
- 2016 - 2019 IRBITファミリーによるpH・塩素イオン濃度制御が神経機能に果たす役割の解明
- 2012 - 2015 Clarifying the role of IRBIT in the coupling regulation of intracellular pH and Ca2+ in astrocytes.
- 2013 - 2014 IIRBITによるCaMKIIa酵素活性制御機構の解明および神経可塑性における機能解析
- 2012 - 2014 Analysis of the pathogenic mechanism for neuropsychiatric disease-like abnormal behavior in IRBIT knockout mouse
- 2010 - 2012 Regulation of CaMKIIa by IP3R-pseudoligand IRBIT
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Papers (22): -
Takashi Nakamura, Katsuhiro Kawaai, Yukiko Kuroda, Koichi Matsuo. Osteoclast visualization: Tartrate-resistant acid phosphatase activity staining using NewFuchsin compatible with non-aqueous mounting and tissue clearing. MethodsX. 2024. 14. 103136-103136
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Yukiko Kuroda, Masaki Yoda, Katsuhiro Kawaai, Motoharu Tatenuma, Toshihide Mizoguchi, Shinichirou Ito, Masataka Kasahara, Yanlin Wu, Hidekazu Takano, Atsushi Momose, et al. Developing long bones respond to surrounding tissues by trans-pairing of periosteal osteoclasts and endocortical osteoblasts. Development. 2024. 151. 17
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Katsuhiro Kawaai, Yumiko Oishi, Yukiko Kuroda, Ryota Tamura, Masahiro Toda, Koichi Matsuo. Chordoma cells possess bone-dissolving activity at the bone invasion front. Cellular Oncology. 2024. 47. 5. 1663-1677
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Katsuhiro Kawaai, Yukiko Kuroda, Koichi Matsuo. Calcified Cartilage-Guided Identification of Osteogenic Molecules and Geometries. ACS Biomaterials Science & Engineering. 2024. 10. 5. 2983-2994
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Yukiko Kuroda, Katsuhiro Kawaai, Naoya Hatano, Yanlin Wu, Hidekazu Takano, Atsushi Momose, Takuya Ishimoto, Takayoshi Nakano, Paul Roschger, Stéphane Blouin, et al. Hypermineralization of hearing-related bones by a specific osteoblast subtype. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2021. 36. 8. 1535-1547
more... MISC (3): - 関口藍理, 浜田浩一, 佐藤聖子, 高橋透泰, 下田沙弥, 波多野直哉, 河合克宏, 御子柴克彦, 水谷顕洋. IRBITは脂肪細胞分化初期の細胞増殖を制御している. 聖マリアンナ医科大学雑誌(Web). 2016. 44. 3. 183 (WEB ONLY)-183
- 安東英明, 廣瀬松美, GAINCHE Laura, 河合克宏, BONNEAU Benjamin, 伊集院壮, 伊藤俊樹, 竹縄忠臣, 御子柴克彦. IRBITはphosphatidylinositol phosphate kinasesの活性中心と結合する. 日本生化学会大会(Web). 2015. 88th
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T. Tashiro, K. Kawaai, K. Tominaga-Yoshino, N. Taniguchi, H. Tashiro, A. Ogura. Genes associated with long-lasting synaptic enhancement in hippocampal slices after repetitive glutamate stimulation. JOURNAL OF NEUROCHEMISTRY. 2007. 102. 276-276
Books (1): - 分子細胞生物学辞典, 第2版
東京化学同人 2008
Lectures and oral presentations (39): -
Chiral alignment of osteoblast populations
(2025)
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Trans-pairing of osteoclasts and osteoblasts facing each other across cortical bone shapes developing bone while maintaining cortical thickness
(2024)
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Establishment of cell chirality analysis methods for situs inversus mice
(2024)
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Effect of single cell cloning on osteoblast chirality spectrum on micropatterns
(2024)
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Morphology of calvarial trabecular bone in mouse, hamster and rabbit
(2024)
more... Professional career (1): Work history (4): - 2024/10 - 現在 Keio University School of Medicine Collaborative Research Resources (Laboratory of Cell and Tissue Biology)
- 2018/07 - 2024/09 Keio University School of Medicine Collaborative Research Resources (Laboratory of Cell and Tissue Biology)
- 2011/04 - 2018/06 RIKEN
- 2009/04 - 2011/03 科学技術振興機構 カルシウム振動プロジェクト 研究員
Association Membership(s) (2):
神経化学会
, JAPANESE SOCIETY FOR BONE AND MINERAL RESEARCH
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