Rchr
J-GLOBAL ID:201101024787082702
Update date: Nov. 13, 2024
Ohnishi Yoshinori N
Ohnishi Yoshinori N
Research field (7):
Pharmacology
, Physiology
, Applied molecular and cellular biology
, Animals: biochemistry, physiology, behavioral science
, Dermatology
, Cognitive neuroscience
, Neuroscience - general
Research keywords (7):
Cocaine addiction
, Depression
, behavior (esp. in romantic relationships)
, Transcription factor
, Creation of genetically engineered mice
, Molecular biology
, behavioral experiments
Research theme for competitive and other funds (14):
- 2022 - 2025 Development of novel therapeutics for neuropsychiatric disorders targeting dopamine signaling
- 2022 - 2025 Elucidating the mechanisms by which female mice identify attractive male mice.
- 2022 - 2025 炎症性疾患によるうつ病発症機序の解明:脳内ドパミンシグナルに着目して
- 2022 - 2025 統合失調症のドーパミン仮説を実現するモデルマウスの神経学的病態機構の解明
- 2019 - 2022 Pharmacological treatment of depression: development of novel therapeutics targeting the dopamine neuronal system
- 2019 - 2022 Involvement of dopamine and noradrenaline signaling mechanisms in depression and schizophrenia.
- 2019 - 2022 Therapeutic action of ghrelin in a mouse model of Rett syndrome -Role of central dopaminergic neurons-
- 2018 - 2020 Novel approaches for treatment of addiction after social defeat stress
- 2016 - 2018 ホスホジエステラーゼを標的とした精神疾患の新規治療法開発
- 2016 - 2018 ドパミン神経系を標的とした精神疾患治療薬の創薬基盤研究
- 2015 - 2017 Does oxdative stress reaction in nucleus accumbes exacerbate cocaine addiction after social defeat stress?
- 2014 - 2016 Regulation of reward-related neural pathways and behavior by ghrelin
- 2012 - 2014 Functional role of the N-terminal domain of DFosB in response to stress and drugs of abuse.
- 2013 - 2013 うつ状態で悪化する依存症を抑制する分子メカニズムの解明
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Papers (43):
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Ryusuke Sin, Naoki Sotogaku, Yoshinori N. Ohnishi, Takahide Shuto, Mahomi Kuroiwa, Yukie Kawahara, Keita Sugiyama, Yuki Murakami, Masaaki Kanai, Hiroshi Funakoshi, et al. Inhibition of STAT-mediated cytokine responses to chemically-induced colitis prevents inflammation-associated neurobehavioral impairments. Brain, Behavior, and Immunity. 2023
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Yuki Kishikawa, Yukie Kawahara, Yoshinori N. Ohnishi, Naoki Sotogaku, Tomoko Koeda, Hiroshi Kawahara, Akinori Nishi. Dysregulation of dopamine neurotransmission in the nucleus accumbens in immobilization-induced hypersensitivity. Frontiers in Pharmacology. 2022. 13
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Yukie Kawahara, Yoshinori N Ohnishi, Yoko H Ohnishi, Hiroshi Kawahara, Akinori Nishi. Distinct Role of Dopamine in the PFC and NAc During Exposure to Cocaine-Associated Cues. International Journal of Neuropsychopharmacology. 2021. 24. 12. 988-1001
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Keita Sugiyama, Mahomi Kuroiwa, Takahide Shuto, Yoshinori N Ohnishi, Yukie Kawahara, Yuta Miyamoto, Takaichi Fukuda, Akinori Nishi. Subregion-Specific Regulation of Dopamine D1 Receptor Signaling in the Striatum: Implication for L-DOPA-Induced Dyskinesia. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2021. 41. 30. 6388-6414
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Yukie Kawahara, Yoshinori Ohnishi, Yoko Ohnishi, Hiroshi Kawahara, Akinori Nishi. Distinct role of dopamine in the PFC and NAc in retrieval of cocaine reward memory. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021. 94. 2-P1
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MISC (21):
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OHNISHI Yoshinori, KAWAHARA Yukie, KISHI Yuki, OHNISHI Yoko, NISHI Akinori. What methods are physiologically or pharmacologically effective for attracting female mice?. 日本薬理学会年会要旨集(Web). 2022. 95th
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KAWAHARA Yukie, OHNISHI Yoshinori, OHNISHI Yoko, KAWAHARA Hiroshi, NISHI Akinori. Distinct role of dopamine in the PFC and NAc during exposure to cocaine-associated cues. 日本薬理学会年会要旨集(Web). 2022. 95th
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大西克典, 河原幸恵, 大西陽子, 西昭徳. Is male mouse attractiveness inherited?. 日本分子生物学会年会プログラム・要旨集(Web). 2021. 44th
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大西克典, 河原幸江, 大西陽子, 西昭徳. 魅力的なオスマウスの剃毛はメスマウスを惹きつける力を失わせか?. 日本薬理学雑誌. 2021. 156. Supplement
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河原幸江, 大西克典, 大西陽子, 河原博, 西昭徳. Differential role of dopamine in the PFC and NAc in cocaine-associated reward memory and behavior. 日本薬理学雑誌. 2021. 156. Supplement
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Lectures and oral presentations (70):
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Ghrelin restores dopamine response via D1 receptor signaling in the PFC in MecP2-deficient mice, a model of Rett syndrome, and improves cognitive deficits
(The 77th Southwest Meeting of the Japanese Pharmacological Society 2024)
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The effect of cocaine on male mouse attractiveness and social ranking.
(The 97th Annual Meeting of the Japanese Pharmacological Society 2023)
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Is the attractiveness of male mice from female mice inherited?
(Neuroscience 2023 2023)
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Anti-inflammatory drugs that suppress depression-like behavior in mice with systemic inflammation
(The 76th Southwest Meeting of the Japanese Pharmacological Society 2023)
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Female mice's nucleus accumbens dopamine responsiveness changes depending on the attractiveness of male mice.
(The 25th Workshop on Active Amines 2023)
more...
Education (1):
- 1998 - 2003 Kyushu University Graduate school of medical sciences
Association Membership(s) (5):
Japan Neuroscience Society
, Society of Neuroscience
, The Molecular Biology Society of Japan
, The Japanese Pharmacological Society
, The Japanese Dermatological Association
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