2014 - 2016 Reverse Glycomics Clarification of Resistance Mechanism for Leukemia Cell and Development of Diagnosis Method for Antitumor Drug Resistance
2013 - 2015 Development of a next generation-diagnostic system for allergic disorders, a component-resolved diagnosis, to create personalized vaccines for allergen-specific immunotherapy
2011 - 2012 Reverse Glycomic Approach for Development of Simple Diagnostic Method of Antitumor-Drug Resistance
L-fucose投与によるIgGの量の制御と分子機序の解明
ムチン型糖タンパク質中の超高速糖鎖切り出し法
Ultra-fast releasing reaction of glycans from mucin-type glycoprotein
蛍光標識化したフェツインのオリゴ糖の分析
Analysis and Specific Distribution of Sialic Acid in Animal tissues
Analysis of fluorescent labeled oligosaccharides from Fetuin
動物組織中のシアル酸分析とその特異的分布について
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Papers (93):
Norihiro Kotani, Shun Shinomiya, Tomoko Amimoto, Miyako Nakano, Kazuyuki Nakagome, Makoto Nagata. Assays for surface antigens in extracellular vesicles using proximity labeling strategy. Methods in Cell Biology. 2024
Sun Y, Xu X, Wu T, Fukuda T, Isaji T, Morii S, Nakano M, Gu J. Core fucosylation within the Fc-FcrR degradation pathway promotes enhanced IgG levels via exogenous L-fucose. J Biol Chem. 2024
Yuta Hashimoto, Haruka Kawade, WanXue Bao, Sayaka Morii, Miyako Nakano, Masamichi Nagae, Reiko Murakami, Yuko Tokoro, Misaki Nakashima, Zixuan Cai, et al. The K346T mutant of GnT-III bearing weak in vitro and potent intracellular activity. Biochimica et biophysica acta. General subjects. 2024. 130663-130663
Tokoro Y, Nagae M, Nakano M, Harduin-Lepers A, Kizuka Y. LacdiNAc synthase B4GALNT3 has a unique PA14 domain and suppresses N-glycan capping. J Biol Chem. 2024
Xu X, Fukuda T, Takai J, Morii S, Sun Y, Liu J, Ohno S, Isaji T, Yamaguchi Y, Nakano M, Moriguchi T, Gu J. Exogenous l-fucose attenuates neuroinflammation induced by lipopolysaccharide. J Biol Chem. 2024. 300. 1. 105513-105513
長田菜緒子, 長江雅倫, 長江雅倫, 中の三弥子, MISHRA Sushil K., DOERKSEN Robert J., 木塚康彦, 木塚康彦. Recognition of self N-glycan by lectin domain of GnT-IV glycosyltransferase. 日本糖質学会年会要旨集. 2023. 42nd
橋本雄太, 川出遥加, 森井爽, 中の三弥子, 長江雅倫, 長江雅倫, 木塚康彦, 木塚康彦. Analysis of the regulatory mechanisms of intracellular activity of GnT-III K346T mutant. 日本糖質学会年会要旨集. 2023. 42nd
Glycoproteomic analysis for identification of glycosites for GnT-V reaction
(Glyco-core Symposium 2024 2024)
Glycoprotoemic and Glycomic analysis of haptoglobin: possible implication for the differential diagnosis of cancer
(Korean Human Proteome Organization 2024 (KHUPO2024) 2024)
糖転移酵素GnT IV のレクチンドメインによる自己N 型糖鎖の認識
(第42回日本糖質学会年会 2023)
糖転移酵素GnT III K346T 変異体の細胞内における活性制御機構の解析
(第42回日本糖質学会年会 2023)
2001 - 2002 Johns Hopkins University Biology Dept. Exchange student for collaboration researchch
1997 - 1999 Kindai University
1992 - 1997 Kindai University
Professional career (2):
Doctor of Philosophy in Pharmaceutical Science (Kindai University)
Master of Pharmaceutical Science (Kindai University)
Work history (8):
2021/09/01 - Osaka International Cancer Institute Visiting researcher
2021/07/01 - The Japanese Society of Carbohydrate Research board member
2019/04/01 - Kumamoto University Visiting lecturer
2019/04/01 - Hiroshima University Graduate School of Integrated Sciences for Life Associate Professor
2012/06/01 - 2019/03/31 Hiroshima University Graduate School of Advanced Sciences of Matter Associate Professor
2011/04/01 - 2018/03/31 RIKEN Visiting researcher
2010/04/01 - 2012/05/31 Hiroshima University Graduate School of Advanced Sciences of Matter Assistant Professor
2010/07/01 - 2011/03/31 Osaka University SANKEN Invited faculty member
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Awards (4):
2017/11/04 - Hirohima University Phoenix Outstanding Researcher Award
2014/09/17 - 日本分析化学会 展望とトピック賞 糖鎖で癌、抗癌剤の効き目がわかる
2013 - 広島大学 広島大学女性研究者奨励賞
2005/07/20 - Japanese Carbohydrate Symposium Poster award Analysis of fluorescent labeled N-glycans by on-line ESI MS
Association Membership(s) (6):
The Mass Spectrometry Society of Japan
, Human Proteome Organization (HUPO)
, The Japan Society for Analytical Chemistry
, The Japanese Cancer Association
, The Japanese Society of Carbohydrate Research
, The Pharmaceutical Society of Japan