Rchr
J-GLOBAL ID:201101053640220646
Update date: Feb. 01, 2024
Uemura Takeshi
ウエムラ タケシ | Uemura Takeshi
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://kaken.nii.ac.jp/ja/r/00372368
Research field (1):
Neuroscience - general
Research keywords (13):
包括脳ネットワーク
, グルタミン酸受容体
, 小脳
, シナプス形成
, 小脳神経回路網形成
, δ2サブユニット
, 神経伝達物質・受容体
, 神経科学
, 脳領域特異的遺伝子ノックアウト
, シナプス可塑性
, ネットワーク形成
, ノックアウトマウス
, 運動学習
Research theme for competitive and other funds (15):
- 2022 - 2027 Elucidation of unique biological reactions to carbon nanoparticles and world's first clinical application and safety assessment of an innovative biomaterials
- 2022 - 2025 シナプス形成因子によるシナプス個性決定の分子基盤
- 2020 - 2023 脊髄損傷性運動麻痺の機能回復におけるリゾリン脂質の役割とそのメカニズム
- 2019 - 2022 脳神経回路網形成と機能制御の分子基盤
- 2013 - 2017 Molecular mechanisms of presynaptic differentiation
- 2013 - 2016 小脳神経回路網形成の分子基盤の解明
- 2012 - 2015 Investigation of mental disorder-related molecules through brain synapse formation mechanisms
- 2010 - 2015 Neocortical layer structure and function
- 2014 - 2015 シナプス形成・成熟過程における分子動態・微細構造の解析技術の開発
- 2013 - 2014 GluRδ2-Cbln1-NRXN複合体によるシナプス形成機構の構造基盤の解明
- 2011 - 2012 シナプス形成におけるGluRδ2ーCbln1ーNRXN三者複合体の構造学的解析
- 2010 - 2011 グルタミン酸受容体(GluR)δ2を介したシナプス形成の分子機構の解明
- 2008 - 2009 グルタミン酸受容体 (GluR)δ2のN末端細胞外領域の機能解明
- 2005 - 2009 Molecular Analysis of Brain System Controls under the Pure Genetic Background
- 2006 - 2007 グルタミン酸受容体(GluR)δ2のシグナル伝達機構の解明
Show all
Papers (52):
-
Yu Usuda, Takumi Okihara, Shigeaki Moriyama, Takeshi Uemura, Takayuki Kamanaka, Aoi William Omi, Naoto Saito, Jun Takahashi, Kaoru Aoki, Naoyuki Nishimura. Development of phosphate-treated PEEK implants with high osseointegration. Materials Today Communications. 2024. 38. 107717-107717
-
Amy Cheung, Kotaro Konno, Yuka Imamura, Aya Matsui, Manabu Abe, Kenji Sakimura, Toshikuni Sasaoka, Takeshi Uemura, Masahiko Watanabe, Kensuke Futai. Neurexins in serotonergic neurons regulate neuronal survival, serotonin transmission, and complex mouse behaviors. eLife. 2023. 12
-
Tamotsu Tsukahara, Hisao Haniu, Takeshi Uemura, Yoshikazu Matsuda. Oxidative Stress and Inflammation: From Mechanisms to Therapeutic Approaches. Biomedicines. 2022. 149-162
-
Naoto Saito, Hisao Haniu, Kaoru Aoki, Naoyuki Nishimura, Takeshi Uemura. Future Prospects for Clinical Applications of Nanocarbons Focusing on Carbon Nanotubes. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022. 9. 24. e2201214
-
Takeshi Uemura, Emi Suzuki-Kouyama, Shiori Kawase, Taiga Kurihara, Misato Yasumura, Tomoyuki Yoshida, Shuya Fukai, Maya Yamazaki, Peng Fei, Manabu Abe, et al. Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins. Cell Reports. 2022. 39. 1. 110624-110624
more...
MISC (26):
-
深井周也, 植村 健, 吉田知之. シナプス形成を誘導する膜受容体の機能と構造. 実験医学 増刊. 2014. 32. 92-97
-
植村健. 大気圧走査電子顕微鏡を用いたシナプス構造と分子局在の解析. 顕微鏡. 2014. 49. 7-9
-
UEMURA Takeshi. Molecular Mechanism of Synapse Formation by Synaptic Organizer. Seibutsu Butsuri. 2013. 53. 2. 090-093
-
Sung-Jin Lee, Takeshi Uemura, Tomoyuki Yoshida, Masayoshi Mishina. GluR delta 2 induces tetramerization of Neurexins to Trigger Synapse Formation. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 66P-66P
-
Tomoyuki Yoshida, Misato Yasumura, Takeshi Uemura, Sung-Jin Lee, Moonjin Ra, Ryo Taguchi, Yoichiro Iwakura, Masayoshi Mishina. IL1RAPL1 associated with mental retardation and autism induces excitatory synapse formation through trans-synaptic interaction with PTP delta. JOURNAL OF PHARMACOLOGICAL SCIENCES. 2012. 118. 232P-232P
more...
Books (1):
-
Synapse formation in the brain
Springer Japan 2013
Professional career (1):
Work history (7):
- 2023/04 - 現在 Shinshu University Research Center for Advanced Science and Technology Professor
- 2017/10 - 2023/03 Shinshu University Research Center for Advanced Science and Technology
- 2014/04 - 2017/09 Shinshu University
- 2013/01 - 2014/03 Shinshu University School of Medicine, Department of Molecular and Cellular Physiology
- 2007/04 - 2012/12 The University of Tokyo Graduate School of Medicine
- 2005/01 - 2007/03 The University of Tokyo Graduate School of Medicine
- 2003/04 - 2004/12 The University of Tokyo Graduate School of Medicine
Show all
Association Membership(s) (3):
Society for Neuroscience
, 日本薬理学会
, 日本神経科学学会
Return to Previous Page