KIYAMA Yuji

Research theme for competitive and other funds (7)：

2021 - 2024 インビボ神経イメージングによる敗血症関連脳症に関与する大脳神経回路同定と治療戦略
2021 - 2024 In vitro, in vivo functions and involvement in schizophrenia of lipid modifying enzyme that shows activity-dependent expression
2019 - 2022 ストレス下で心の平穏を保つための脳神経回路
2015 - 2019 活動神経のプロファイリングを通じた扁桃体機能解析
2011 - 2014 ドミナント・ネガティブ型Creを応用した扁桃体特異的遺伝子KOマウスの作成と解析

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Papers (27)：

Mohieldin M. M. Youssef, Hiro Taiyo Hamada, Esther Suk King Lai, Yuji Kiyama, Mohamed El-Tabbal, Hiroshi Kiyonari, Kohei Nakano, Bernd Kuhn, Tadashi Yamamoto. TOB is an effector of the hippocampus-mediated acute stress response. Translational Psychiatry. 2022. 12. 1
城山優治, 後藤史子, 小川糸音, 吉田進昭, 尾藤晴彦, 真鍋俊也, 奥野浩行. Gastrin-releasing peptideは急性ストレス下で、amygdalostriatal transition areaを通じて恐怖学習を調節する. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 1P-353
Keita Mori, Michinori Koebis, Kazuki Nakao, Shizuka Kobayashi, Yuji Kiyama, Masahiko Watanabe, Toshiya Manabe, Yuichi Iino, Atsu Aiba. Loss of calsyntenin paralogs disrupts interneuron stability and mouse behavior. Molecular brain. 2022. 15. 1. 23-23
Fumiko Goto, Yuji Kiyama, Itone Ogawa, Hiroyuki Okuno, Taeko Ichise, Hirotake Ichise, Motonobu Anai, Tatsuhiko Kodama, Nobuaki Yoshida, Haruhiko Bito, et al. Gastrin-releasing peptide regulates fear learning under stressed conditions via activation of the amygdalostriatal transition area. Molecular psychiatry. 2022. 27. 3. 1694-1703
Tetsuo Ohnishi, Yuji Kiyama, Fumiko Arima-Yoshida, Mitsutaka Kadota, Tomoe Ichikawa, Kazuyuki Yamada, Akiko Watanabe, Hisako Ohba, Kaori Tanaka, Akihiro Nakaya, et al. Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia. EMBO molecular medicine. 2021. 13. 4. e12574

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MISC (31)：

大徳晋久, 比嘉なつみ, 城山優治, 奥野浩行, 松永明. Changes in calcium responses overtime in single neurons in the primary somatosensory cortex in response to pain stimuli revealed by in vivo calcium imaging using a head-mounted fluorescence microscope. 日本麻酔科学会学術集会(Web). 2023. 70th
大江将軍, 大徳晋久, 城山優治, 上村裕一, 奥野浩行, 松永明. Changes in calcium responses during isoflurane inhalation anesthesia in the mouse hippocampus using a miniaturized fluorescence microscope. 日本麻酔科学会学術集会(Web). 2023. 70th
城山優治, 城山優治, 後藤史子, 小川糸音, 吉田進昭, 尾藤晴彦, 真鍋俊也, 奥野浩行, 奥野浩行. Gastrin-releasing peptideは急性ストレス下で,amygdalostriatal transition areaを通じて恐怖学習を調節する. 日本生化学会大会(Web). 2022. 95th
後藤史子, 城山優治, 城山優治, 小川糸音, 奥野浩行, 吉田進昭, 尾藤晴彦, 真鍋俊也. Gastrin-releasing peptideはamygdalostriatal transition areaを活性化させ,ストレス負荷時の恐怖学習を調節する. 日本神経化学会大会抄録集(Web). 2022. 65th
大西哲生, 大西哲生, 光増真広, 城山優治, 城山優治, 有馬(吉田)史子, 有馬(吉田)史子, 門田満隆, 岩山佳美, 市川智恵, et al. 精神疾患の発症機序と新規遺伝子発現調節系「LDB2-EGR軸」の関連性. 日本神経化学会大会抄録集(Web). 2022. 65th

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