Rchr
J-GLOBAL ID:201101082088016907
Update date: Apr. 14, 2025 Hayashi Yasunori
ハヤシ ヤスノリ | Hayashi Yasunori
Affiliation and department: Job title:
Professor
Homepage URL (2): http://glutamate.med.kyoto-u.ac.jp/j/
,
http://glutamate.med.kyoto-u.ac.jp/ Research field (1):
Neuroscience - general
Research keywords (18):
Förster-resonance energy transfer
, two-photon microscopy
, glutamate receptor
, hippocampus
, synaptic plasticity
, hippocampal slice
, long-term potentiation
, calcium/calmodulin-dependent protein kinase (CaMKII)
, virus vector
, actin
, dendritic spine
, sleep
, learning and memory
, calcium
, cellular signal transduction
, cytoskeleton
, cofilin
, two-photon laser scanning microscope
Research theme for competitive and other funds (24): - 2022 - 2029 記憶メカニズムの多次元解析 - nmからメゾスケール/ミリ秒から日スケールまで
- 2022 - 2027 Cellular representation of abstractive space "spatial context cells" - their formation and role in long-term memory
- 2022 - 2025 空間概念の細胞表現「空間文脈細胞」の形成機構と長期空間記憶における役割
- 2020 - 2025 記憶を司るシナプス微小構造の時空間ダイナミクス
- 2018 - 2023 シナプス操作によるPTSDの構成的理解
- 2018 - 2023 マルチスケール精神病態の構成的理解(総括班)
- 2020 - 2022 Regulatory mechanism of synaptic plasticity through liquid-liquid phase separation of CaMKII
- 2019 - 2022 Circuit mechanism of spatial context information processing
- 2018 - 2019 光による特定の神経細胞への記憶のエンコーディング
- 2017 - 2019 Role of hippocampal predictive firing in decision making
- 2016 - 2019 シナプス可塑性の基盤となるカルシウムシグナルの可視化
- 2016 - 2019 Time-window of NMDA receptor-dependent LTP during memory formation, consolidation and recall
- 2016 - 2018 NMDA受容体依存性LTPの制御のための光プローブの作成
- 2016 - 2018 記憶形成、固定、想起における海馬背側CA1セルアセンブリの長期可視化
- 2015 - 2018 Visualization of maternal separation memory engram and retrieval by activating positive memory engram
- 2016 - 2017 Neural circuit mechanism to determine hippocampal brain state
- 2015 - 2017 記憶形成の感情によるゲートの神経メカニズム
- 2015 - 2016 Why there are multiple synaptic adhesion molecules in single synapse? - Nanodomain hypothesis
- 2014 - 2015 Role of clonally-related neurons in hippocampal neuronal circuit
- 2010 - 2015 Development of deep brain imaging technology in behaving animals: stability and instability of neuronal circuit under physiological and pathophysiological conditions
- 2011 - 2014 Effects of early life stress on brain plasticity
- 2008 - 2012 Molecular mechanisms of structural plasticity of dendritic spine
- 2011 - 2011 Optogenetic approach of gene regulation
- 2009 - 2009 睡眠中の海馬活性化の記憶固定に於ける意義
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Papers (133): -
Timon Kunze, Alessandro Treves. Neural computation in the mammalian hippocampus. 2025
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Junyu Liu, Akihiro Goto, Yasunori Hayashi. Time-window of offline long-term potentiation in anterior cingulate cortex during memory consolidation and recall. Neuroscience Research. 2024
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Vikas Pandey, Tomohisa Hosokawa, Yasunori Hayashi, Hidetoshi Urakubo. The role of protein shape in multiphasic separation within condensates. 2024
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Yasunori Hayashi, Miquel Bosch, Pin-Wu Liu, Tomohisa Hosokawa, Takeo Saneyoshi. Molecular Mechanisms Underlying Synaptic Tagging and Consolidation. Synaptic Tagging and Capture. 2024. 63-76
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Takeshi Kaizuka, Taisei Hirouchi, Takeo Saneyoshi, Toshihiko Shirafuji, Mark O. Collins, Seth G. N. Grant, Yasunori Hayashi, Toru Takumi. FAM81A is a postsynaptic protein that regulates the condensation of postsynaptic proteins via liquid-liquid phase separation. PLOS Biology. 2024. 22. 3. e3002006
more... MISC (41): -
実吉 岳郎, 林 康紀, リポリ・クリスチャン, 末松 千咲音. アクチン細胞骨格の生物学・疾患における多面性と普遍性 樹状突起スパイン内部のコフィリンは液-液相分離によって分子活性のグラディエントを形成する. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1S08e-02]
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林 康紀. 記憶の固定と消去のメカニズム 記憶形成に伴うonline LTPとoffline LTP. 老年精神医学雑誌. 2022. 33. 増刊II. 205-205
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林 康紀. 記憶の固定と消去のメカニズム 記憶形成に伴うonline LTPとoffline LTP. Dementia Japan. 2022. 36. 4. 728-728
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後藤明弘, 林康紀. 光によるシナプス可塑性制御で明らかになった記憶固定化機構. 生物物理 (日本生物物理学会). 2022. 62. 4. 239-241
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Yasunori Hayashi, Tomohisa Hosokawa, Pin Wu Liu, Takeo Saneyoshi. Novel mechanism of synaptic plasticity mediated by CaMKII. Seikagaku. 2021. 93. 2. 191-202
more... Lectures and oral presentations (2): -
Molecular mechanism of structural plasticity of dendritic spine
(Universidad autonoma de Madrid, Spain 2011)
-
Phosphoisotype analysis of AMPA receptor GluR1
(Gordon Research Conference Excitatory Synapsese & Brain Function 2011)
Education (2): - 1990 - 1994 Kyoto University Graduate School of Medicine
- 1984 - 1990 Kyoto University Faculty of Medicine
Professional career (2): - MD (Kyoto University)
- PhD (Kyoto University)
Work history (5): - 2016 - 現在 Kyoto University Graduate School of Medicine Professor
- 2009 - 2017 RIKEN Brain Science Institute Team Leader
- 2000 - 2009 Massachusetts Institute of Technology RIKEN-MIT Neuroscience Research Center Assistant Professor
- 1996 - 2000 Cold Spring Harbor Laboratory Postdoctral Fellow
- 1994 - 1996 Tokyo University School of Medicine JSPS postdoctral fellow
Awards (6): Association Membership(s) (4):
The Physiological Society of Japan
, The Japanese Pharmacological Society
, The Japan Society for Neuroscience
, Society for Neuoscience
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