Rchr
J-GLOBAL ID:201101083527736837
Update date: Nov. 12, 2024
Kenji Tanaka
タナカ ケンジ | Kenji Tanaka
Affiliation and department:
Job title:
Professor
Homepage URL (1):
http://psy-keiomed-ect.com/index.html
Research field (1):
Neuroscience - general
Research keywords (7):
ventral striatum
, ventral hippocampus
, motivation
, optogenetics
, fiberphotometry
, KENGE-tet
, FASTシステム
Research theme for competitive and other funds (35):
- 2024 - 2028 Effects of changes in barometric pressure on mood fluctuations and somatisation: Basic and clinical approaches
- 2020 - 2025 グリア・神経ネットワークの統合による脳内エネルギー代謝機構
- 2020 - 2025 Glia decoding: deciphering information critical for brain-body interactions
- 2018 - 2022 Establishment and applications of model mice with fluctuated deafness by advanced gene-engineering methods
- 2019 - 2021 意欲行動の持続にかかわる神経基盤の解明
- 2017 - 2020 Investigation of role of serotonergic neurons in regulation of masseter muscle activity using optogenetics
- 2018 - 2019 グリアアセンブリによる脳機能発現の制御と病態
- 2017 - 2019 負に立ち向かうウィルパワーをつかさどる神経基盤の解明
- 2016 - 2019 Understanding a role of cerebral angiogenesis and hyperemia on cognitive decline
- 2015 - 2019 Regulatory role of BDNF on emotional and cognitive function
- 2016 - 2018 The experimental attempt for brain evolution by increase of neurons in mouse cerebral cortex
- 2016 - 2018 線条体におけるカルシウム振動の描出と生理学的意義の解明
- 2015 - 2018 Project to create international glial researcher network: mainly focusing on Japan-Germany research exchange
- 2015 - 2018 Estimation of neural activity propagation pathway in the brain by applying deep learning
- 2015 - 2018 Control of stria vascularis function and changes of auditory and vestibular function induced by optogenetic stimulation
- 2015 - 2018 How does the cerebellum work during cognitive and emotional tasks?
- 2015 - 2018 Screening and analysis of glial factors for neuroprotection
- 2014 - 2018 A role of astrocyte in neuro-glio-vascular unit concerning cerebral microcirculation
- 2013 - 2018 Studies on communication between neuroaxons via oligodendrocytes.
- 2014 - 2017 Visualization and quantification of fluxes of glucose metabolic pathways in brain
- 2014 - 2017 Analysis of cerebral blood flow regulation using in vivo fluorescence imaging
- 2014 - 2017 Transcriptional repressor RP58 as neuronal maturation and maintenance
- 2013 - 2017 Testing serotonin hypothesis of depression with optogenetics
- 2013 - 2016 Investigation of brain-wide responses evoked by optogenetic activation of the dorsal or ventral hippocampus
- 2010 - 2016 Comprehensive Brain Science Network
- 2013 - 2015 うつ病における神経回路変容の抽出と解析
- 2011 - 2015 Oligodendrocyte-neuron interaction
- 2012 - 2014 グリア細胞操作を起点とする神経活動変化と伝播様式解析
- 2012 - 2014 The interaction between serotonergic and cannabinoidergic neurotransmissions in the basolateral amygdala
- 2012 - 2014 Development of animal model enabling the manipulation of intracellular Ca level
- 2011 - 2014 Study for neural mechanism of wakefulness and dependence using optogenetics
- 2011 - 2014 Localization of excitatory and inhibitory astrocytes, and their generation mechanism
- 2009 - 2010 光分子センサー・メラノプシンの神経細胞種依存的な活性化機構のモーダルシフトと応用
- 2009 - 2010 Analysis of astrocytic function by using STOP-tetO system
- 2003 - 2007 ニューロン-グリア相互作用に関与する機能分子の探索
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Papers (210):
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Hitomi Kurahashi, Kazuo Kunisawa, Kenji F. Tanaka, Hisayoshi Kubota, Masaya Hasegawa, Mai Miyachi, Yuka Moriya, Yoichi Hasegawa, Taku Nagai, Kuniaki Saito, et al. Autism spectrum disorder-like behaviors induced by hyper-glutamatergic NMDA receptor signaling through hypo-serotonergic 5-HT1A receptor signaling in the prefrontal cortex in mice exposed to prenatal valproic acid. Neuropsychopharmacology. 2024
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Hiroki Suzuki, Juri Murata, Miyuki Unekawa, Iwao Kanno, Yoshikane Izawa, Yutaka Tomita, Kenji F. Tanaka, Jin Nakahara, Kazuto Masamoto. Microfluctuations in Capillary Lumens Independent of Pericyte Lining Density in the Anesthetized Mouse Cortex. Microcirculation. 2024
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Manal S. Abdelaal, Tomonobu Kato, Akiyo Natsubori, Kenji F. Tanaka. Temporal and Potential Predictive Relationships between Sleep Spindle Density and Spike-and-Wave Discharges. eneuro. 2024. 11. 9. ENEURO.0058-24.2024
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Eiji Shigetomi, Hideaki Suzuki, Yukiho J. Hirayama, Fumikazu Sano, Yuki Nagai, Kohei Yoshihara, Keisuke Koga, Toru Tateoka, Hideyuki Yoshioka, Youichi Shinozaki, et al. Disease-relevant upregulation of P2Y1 receptor in astrocytes enhances neuronal excitability via IGFBP2. Nature Communications. 2024. 15. 1
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Xuan Thang Pham, Yoshifumi Abe, Yasutaka Mukai, Daisuke Ono, Kenji F Tanaka, Yu Ohmura, Hiroaki Wake, Akihiro Yamanaka. Glutamatergic signaling from melanin-concentrating hormone-producing neurons: A requirement for memory regulation, but not for metabolism control. PNAS Nexus. 2024. 3. 7
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MISC (160):
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田中 謙二. アパシーの成因・治療を考える アパシーの脳内基盤 リバーストランスレーショナル研究. 老年精神医学雑誌. 2021. 32. 増刊I. 177-177
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松瀬 大, 山口 浩雄, 眞崎 勝久, 西村 由宇慈, 田中 辰典, 雑賀 徹, 田中 謙二, 山崎 亮, 吉良 潤一, 磯部 紀子. 新規小脳型多系統萎縮症モデルのCSF-1R阻害剤治療. パーキンソン病・運動障害疾患コングレスプログラム・抄録集. 2021. 15回. 92-92
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松瀬 大, 山口 浩雄, 眞崎 勝久, 西村 由宇慈, 田中 辰典, 雑賀 徹, 田中 謙二, 山崎 亮, 吉良 潤一. オリゴデンドロサイト特異的αシヌクレイン蓄積による小脳型多系統萎縮症モデルの樹立. パーキンソン病・運動障害疾患コングレスプログラム・抄録集. 2021. 14回. 110-110
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木村 範子, 河野 佐代子, 滝上 紘之, 山市 大輔, 片山 奈理子, 竹内 啓善, 菊地 俊暁, 佐渡 充洋, 内田 裕之, 田中 謙二, et al. COVID-19こころのケアチーム活動報告. 総合病院精神医学. 2020. 32. Suppl. S-193
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田中 謙二, 阿部 欣史, 權 秀珍, 大石 光洋. 新しい役者を標的にした脳卒中研究の新潮流-グリア細胞、神経幹細胞、血管壁細胞- 血管壁細胞の光操作. 脳循環代謝. 2020. 32. 1. 54-54
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Lectures and oral presentations (44):
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the 5th BRI International Symposium: Genome editing technology; its status quo and application to brain research
(the 5th BRI International Symposium: Genome editing technology; its status quo and application to brain research 2015)
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特定細胞集団の活動を操作する、観察する
(都医学研セミナー 2015)
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第25回マイクロダイアリシス研究会
(第25回マイクロダイアリシス研究会 2014)
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精神医学研究にオプトジェネティクスが期待されること
(第35回日本レーザー医学会総会 2014)
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Microglia transform astrocytes into neuroprotective phenotypes by inhibiting P2Y1 receptors.
(第57回日本神経化学会大会 2014)
more...
Works (2):
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ゆとりの時間「Let's Enjoy High School Science」
田中謙二 2013 - 現在
-
夏休みの研究体験
2013 - 2013
Professional career (2):
- 博士(医学) (慶應義塾)
- Doctor (Medicine) (Keio University)
Work history (5):
- 2016/01 - 現在 Keio University School of Medicine
- 2012 - 2015/12 慶應義塾大学医学部 精神神経科 特任准教授
- 2006 - 2008 Columbia University
- 2008 - National Institute for Physiological Sciences
- 2005 - National Institute for Physiological Sciences Department of Molecular Physiology
Association Membership(s) (2):
日本精神神経学会
, THE JAPANESE SOCIETY FOR NEUROCHEMISTRY
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