Research theme for competitive and other funds (10):
2021 - 2024 Clarification of Cdh1 mediated inflammatory carcinogenesis mechanism revealed by spatial gene expression analysis and development of novel preventive strategies.
2018 - 2021 Investigation on prediction for medical treatment response to advanced hepatocellular carcinoma
2018 - 2021 Analysis of metabolic reprogramming induced by cellular environment and its application to control hepato-carcinogenesis
2017 - 2020 Regulation of invasion and metastasis of colon cancer via Wnt-Cdh1 axis
2014 - 2017 molecular biological analysis of Sessile serrated adenoma/polyp in the proximal colon
2013 - 2017 Analysis of microenvironment-mediated treatment resistance of hepatocellular carcinoma in terms of integrated proteomics
2014 - 2017 The role of Cdh1 in colorectal cancer invasion and metastasis
2012 - 2015 Basic study of the cell cycle related molecules affiliated with liver regeneration and clinical application
2012 - 2014 The role of cell cycle regulator Cdh1 in carcinogenesis and development of gastrointestinal cancer.
2009 - 2012 Analysis of mechanisms underlying treatment-resistance ofhepatocelluar carcinoma in the point view of post-translationalmodification evaluated by proteomics
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Papers (44):
Munenori Honda, Yasushi Oda, Ryosuke Gushima, Hideaki Miyamoto, Hideaki Naoe, Kiwamu Hasuda, Kouichi Sakurai, Yoshitaka Murakami, Yasuhito Tanaka. Impact of Surveillance Colonoscopy Timing on Colorectal Cancer Incidence Following Advanced Adenoma Resection. The American journal of gastroenterology. 2025
Sayoko Tayama, Hideaki Miyamoto, Kotaro Waki, Munenori Honda, Kenshi Matsuno, Akira Yamasaki, Ryosuke Gushima, Katsuya Nagaoka, Hideaki Naoe, Masanori Imuta, et al. Impact of HPV status on oropharyngeal cancer detection via gastrointestinal endoscopy: a retrospective study. International journal of clinical oncology. 2025
Kotaro Waki, Katsuya Nagaoka, Keishi Okubo, Masato Kiyama, Ryosuke Gushima, Kento Ohno, Munenori Honda, Akira Yamasaki, Kenshi Matsuno, Yoki Furuta, et al. Optimizing AI models to predict esophageal squamous cell carcinoma risk by incorporating small datasets of soft palate images. Scientific reports. 2025. 15. 1. 4003-4003
Shinya Yamaga, Naotaka Kugiyama, Shunpei Hashigo, Katsuya Nagaoka, Rin Yamada, Shinya Ushijima, Yukiko Uramoto, Motohiro Yoshinari, Hideaki Naoe, Yasuhito Tanaka. Amputation neuroma with a difficult differential diagnosis from perihilar cholangiocarcinoma: a case report. Journal of Japanese Society of Gastroenterology. 2024. 121. 10. 842-850
Multi-omics analyses identify Nucleophosmin as a key regulator of apoptosis resistance in human hepatocellular carcinoma
(AASLD, The Liver Meeting 2019)
肝癌の治療抵抗性を担う責任分子の同定と機能解析
(第52回日本肝臓学会総会 2016)
Proteomics analyses identified a phosphoprotein relevant to apoptosis resistance in human hepatoma
(The Asian Pacific Association for the Study of the Liver [APASL] 2016)
Proteomics analyses identified a phosphoprotein relevant to apoptosis resistance in human hepatoma
(2015)
The APC/C activator Cdh1 modulates actin cytoskeleton by targeting p190RhoGAP for degradation (Kumamoto University)
Work history (4):
2021/04 - 現在 熊本大学大学院生命科学研究部 消化器内科 准教授
2018/11 - 2021/03 Kumamoto University Gastroenterology and Hepatology Lecturer
2010 - 熊本大学医学部附属病院消化器内科 助教
2010 - Assistant Professor, ,University Hospital ,Kumamoto University
Committee career (2):
2018/01 - 現在 日本消化器病学会 学会評議員
2013/01 - 現在 日本消化器病学会 九州支部評議員
Association Membership(s) (5):
THE JAPAN SOCIETY OF HEPATOLOGY
, JAPAN GASTROENTEROLOGICAL ENDOSCOPY SOCIETY
, JAPANESE SOCIETY OF GASTROENTEROLOGY
, THE JAPANESE SOCIETY OF INTERNAL MEDICINE
, 日本がん治療認定医機構