Rchr
J-GLOBAL ID：201101099574664147
Update date: Aug. 21, 2024
Kohei Arasaki
アラサキ コウヘイ | Kohei Arasaki
Affiliation and department：
Homepage URL (1)：
http://www.ls.toyaku.ac.jp/Life-Science/lmcb-6/
Research field (3)：
Bacteriology
, Cell biology
, Molecular biology
Research keywords (3)：
レジオネラ感染
, 膜融合
, 細胞内小胞輸送
Research theme for competitive and other funds (18)：
- 2020 - 2023 Management of PLAMP research
- 2020 - 2023 レジオネラの宿主細胞内における自己化PLAMPの解明
- 2023 - オルガネラコンタクトを通じたレジオネラ治療薬の探索
- 2022 - 小胞輸送で理解するSARS-CoV-2のウイルス粒子形成機構
- 2022 - 細胞内小胞輸送を基軸とした新型コロナウイルス(SARS-CoV-2)の治療薬の探索
- 2018 - 2021 Identification of intracellular survival mechanisms of Legionella inside the host cell
- 2016 - 2018 病原菌感染や結合タンパク質を介したsyntaxin17の生理機能の解明
- 2014 - 2018 Analysis of intracellular pathogenic pathway of Legionella pneumophila
- 2017 - レジオネラによる宿主細胞制御機構の解明
- 2014 - 2016 レジオネラ菌によるSyntaxin17分解機構とその生理的意義の解明
- 2013 - 2016 Roles of syntaxin 17 in the formation and function of the mitochondria-associated ER membrane
- 2015 - レジオネラの宿主細胞内における多彩な生存戦略の解明
- 2015 - Syntaxin 17を通じて細胞内の生理現象 から感染までを理解する
- 2012 - 2014 Analysis of intracellular pathogenesis of Legionella in the host
- 2013 - レジオネラ菌細胞内発症に関わるRabタンパク質の網羅的探索
- 2011 - レジオネラエフェクタータンパク質の解明
- 2005 - 2006 紡錘体形成チェックポイントに関与するZW10の間期における機能とその活性制御機構
- レジオネラ菌感染におけるLCV膜とER小胞との繋留及び融合反応の解明
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Papers (37)：
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Hiroki Inoue, Taku Kanda, Gakuto Hayashi, Ryota Munenaga, Masayuki Yoshida, Kana Hasegawa, Takuya Miyagawa, Yukiya Kurumada, Jumpei Hasegawa, Tomoyuki Wada, et al. A MAP1B-cortactin-Tks5 axis regulates TNBC invasion and tumorigenesis. The Journal of cell biology. 2024. 223. 3
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Tomoko Kubori, Kohei Arasaki, Tomoe Kitao, Hiroki Nagai. Multi-tiered actions of Legionella effectors to modulate host Rab10 dynamics. 2023
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Misaki Murata, Riku Kanamori, Tomoe Kitao, Tomoko Kubori, Hiroki Nagai, Mitsuo Tagaya, Kohei Arasaki. Requirement of phosphatidic acid binding for distribution of the bacterial protein Lpg1137 targeting syntaxin 17. Journal of cell science. 2022. 135. 6
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Shun Kato, Kohei Arasaki, Natsuki Tokutomi, Yuzuru Imai, Tsuyoshi Inoshita, Nobutaka Hattori, Taeko Sasaki, Miyuki Sato, Yuichi Wakana, Hiroki Inoue, et al. Syntaxin 17, an ancient SNARE paralog, plays different and conserved roles in different organisms. Journal of Cell Science. 2021. 134. 22
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Tomoe Kitao, Kohei Arasaki, Hiroki Nagai, Tomoko Kubori. Protocol for imaging proteins associated with Legionella-containing vacuoles in host cells. STAR protocols. 2021. 2. 2. 100410-100410
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MISC (3)：
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H. Kimura, K. Arasaki, M. Tagaya. Syntaxin 17 promotes lipid droplet formation by regulating the distribution of ACSL3, a key enzyme for lipid droplet biogenesis. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
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K. Arasaki, M. Tagaya, N. Dohmae, Y. Kurosawa, H. Nagashima. MAP1B-LC1 regulates autophagosome formation by interacting with the autophagy-related SNARE syntaxin 17. MOLECULAR BIOLOGY OF THE CELL. 2016. 27
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Kohei Arasaki, Craig Roy. Host SNAREs mediate fusion of vacuoles containing Legionella pneumophila with vesicles exiting the endoplasmic reticulum. FASEB JOURNAL. 2009. 23
Education (3)：
- 2003 - 2006 Tokyo University of Pharmacy and Life Sciences Graduate School of Life Science
- 2001 - 2003 Tokyo University of Pharmacy and Life Sciences Graduate School of Life Science
- 1998 - 2001 Tokyo University of Pharmacy and Life Sciences School of Life Science School of Life Science
Work history (6)：
Awards (1)：
- 2017/12 - 日本生化学会 奨励賞 小胞体SNAREの多様な生理機能
Association Membership(s) (2)：
JAPANESE SOCIETY FOR BACTERIOLOGY
, THE JAPANESE BIOCHEMICAL SOCIETY
