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J-GLOBAL ID:201201028969040510   Update date: Jan. 08, 2025

SAKAGUCHI Masanori

Sakaguchi Masanori | SAKAGUCHI Masanori
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Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): https://sakaguchi-lab.org/
Research field  (1): Cognitive neuroscience
Research keywords  (7): 新生ニューロン ,  記憶 ,  睡眠 ,  海馬 ,  生体脳イメージング ,  光遺伝学 ,  深層学習
Research theme for competitive and other funds  (25):
  • 2022 - 2029 Deciphering the mysteries of sleep:creating a global network of sleep neurobiologists
  • 2024 - 2027 睡眠中の音刺激によるPTSDの新規治療法の開発
  • 2024 - 2027 睡眠中の音刺激による環世界マニピレーション
  • 2023 - 2026 レム睡眠中に恐怖記憶が再想起する意義の解明
  • 2022 - 2025 Molecular Research and Treatment of Fear Memory in PTSD
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Papers (53):
  • Yuteng Wang, Pablo Vergara, Satoshi Hasegawa, Naoki Tomita, Yoan Cherasse, Toshie Naoi, Takeshi Sakurai, Yuki Sugaya, Masanobu Kano, Masanori Sakaguchi. T-scope V4: miniaturized microscope for optogenetic tagging in freely behaving animals. 2024
  • Kaizhen Li, Konstantinos Koukoutselos, Masanori Sakaguchi, Stéphane Ciocchi. Distinct ventral hippocampal inhibitory microcircuits regulating anxiety and fear behaviors. Nature Communications. 2024
  • Mitsuaki Kashiwagi, Goichi Beck, Mika Kanuka, Yoshifumi Arai, Kaeko Tanaka, Chika Tatsuzawa, Yumiko Koga, Yuki C. Saito, Marina Takagi, Yo Oishi, et al. A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease. Cell. 2024
  • Chinatsu Kawakami, Toshie Naoi, Masanori Sakaguchi. Spaced conditioned stimulus presentation facilitates the extinction of strong fear memory in mice. Biochemical and Biophysical Research Communications. 2024. 150071-150071
  • He Z, Vergara P, Tezuka T, Sakaguchi M. Real-Time Detection of Motifs from semi-Synthetic Calcium Imaging Data with Various Noise Types. 2024
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MISC (14):
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Patents (6):
  • 判定装置、光照射装置、及びプログラム
  • 小型撮像装置
  • Agent for inhibiting proliferation of neural stem cells.
  • Methods for enhancing survival and/or proliferation of neural stem cells and neurite extension enhancers therefore pharmaceutical compositions containing neural stem cells assay methods and screening methods.
  • Method of promoting subsistence and/or proliferation of neural stem cell and promoting extension of neurite, promoter therefor, pharmaceutical composition containing neural stem cell, method of assay and method of screening
more...
Books (11):
  • 睡眠学第2版
    朝倉書店 2019
  • トラウマ記憶を弱めるには ? マウスの記憶・睡眠研究から考えるPTSDケア
    AdademistJournal 2017
  • トラウマ直後の環境条件の記憶汎化における重要性-心的外傷後ストレス障害(PTSD)治療における意義
    医歯薬出版(株) 2016
  • 脳内で新生するニューロンと、中枢神経再生への応用
    クバプロ 2016 ISBN:9784878051456
  • Recombinant sugar binding proteins and their functional analysis: Galectin-1
    JCGGDB 2014
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Lectures and oral presentations  (58):
  • Hippocampal Adult-Born Neurons for Memory Consolidation during REM Sleep
    (U of T Brain and Bee seminar 2022)
  • CaliAli (Calcium imaging inter-session alignment): neuronal tracing utilizing vasculature in calcium imaging
    (Frankland lab seminar 2022)
  • Fully automatic sleep stage-specific intervention using single EEG in mice
    (Frankland lab seminar 2022)
  • Transient recruitment of adult-born neurons for fear memory consolidation in REM sleep
    (2022)
  • CaliAli (Calcium imaging inter-session alignment): neuronal tracing utilizing vasculature in calcium imaging
    (2022)
more...
Education (2):
  • 2001 - 2005 Tsukuba University Conprehensive Human Sciences Medicine Doctural Course
  • 1995 - 2001 Tsukuba University School of Medicine Department of Medicine
Professional career (1):
  • 博士(医学) (筑波大学)
Work history (12):
  • 2022/04 - 現在 University of Tsukuba Faculty of Medicine Assc Prof (Tenure)
  • 2021/10 - 現在 National Center of Neurology and Psychiatry
  • 2018/10 - 現在 Tsukuba University International Institute for Integrative Sleep Medicine Associate Professor, PI
  • 2013/04 - 2018/09 Tsukuba University International Institute for Integrative Sleep Medicine Associate Professor, co-PI
  • 2013/02 - 2013/03 Univ. Tsukuba WPI-IIIS Researcher
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Awards (9):
  • 2022/10 - 筑波大学 優秀教員表彰
  • 2021/01 - 2021 Inscopix Tech Award SFN Global connectome
  • 2016 - Society for Neuroscience Neuroscience?2016 HotTopic The role of adult born neurons in memory consolidation during sleep-wake cycles
  • 2015 - The Adult Neurogenesis Conference 優秀発表賞
  • 2014 - Homeodynamics in Clocks, Sleep and Metabolism Tokyo Translational Therapeutics Meeting 優秀発表賞 The role of adult born neurons during sleep
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