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J-GLOBAL ID：201201032871309909 Update date: Apr. 08, 2025

Usui Noriyoshi

ウスイノリヨシ | Usui Noriyoshi

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Affiliation and department：
Job title： Associate Professor

Research field (6)： Developmental biology , Anatomy , Psychiatry , Genomics , Evolutionary biology , Neuroscience - general

Research keywords (18)： Brain , Sociality , Autism spectrum disorders , Dependence , Mind , Behavior , Sex difference , Development , Evolution , ZBTB16 , Transcription factor , Gene expression , Transcriptome , 代謝 , Element , Metallome , 脂質 , オリゴデンドロサイト

Research theme for competitive and other funds (41)：

2024 - 2027 コホート臍帯血と含有微量元素を利用した子どもの発達特性・健康リスク検査法の開発
2023 - 2027 自閉スペクトラム症の病態形成と脳の発達における体内微量元素の役割の解明
2023 - 2027 Generation of a mouse model of nociplastic pain and identification of therapeutic target molecules through analyzing brain mechanisms involved in it
2025 - 2026 社会性行動に関連する線条体神経回路の発生メカニズム解明
2023 - 2026 変異集中領域に着目した自閉スペクトラム症のリバーストランスレーショナルリサーチ

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Papers (41)：

Shogo Togawa, Noriyoshi Usui, Miyuki Doi, Yuki Kobayashi, Yoshihisa Koyama, Yukiko Nakamura, Koh Shinoda, Hikaru Kobayashi, Shoichi Shimada. Neuroprotective effects of Si-based hydrogen-producing agent on 6-hydroxydopamine-induced neurotoxicity in juvenile mouse model. Behavioural Brain Research. 2024. 468. 115040-115040
Noriyoshi Usui. Possible roles of deep cortical neurons and oligodendrocytes in the neural basis of human sociality. Anatomical Science International. 2024. 99. 1. 34-47
Noriyoshi Usui, Miyuki Doi, Stefano Berto, Kiwamu Matsuoka, Rio Ishida, Koichiro Irie, Nanako Nakama, Hana Miyauchi, Yuuki Fujiwara, Takahira Yamauchi, et al. Copper-deficiency is associated with impairments in social behavior and oligodendrocyte development via mTOR signaling pathway. medRxiv. 2023
Nagahide Takahashi, Tomoko Nishimura, Taeko Harada, Akemi Okumura, Toshiki Iwabuchi, Md Shafiur Rahman, Hitoshi Kuwabara, Shu Takagai, Noriyoshi Usui, Manabu Makinodan, et al. Interaction of genetic liability for attention deficit hyperactivity disorder (ADHD) and perinatal inflammation contributes to ADHD symptoms in children. Brain, Behavior, & Immunity - Health. 2023. 30. 100630
Nanako Nakama, Noriyoshi Usui, Miyuki Doi, Shoichi Shimada. Early life stress impairs brain and mental development during childhood increasing the risk of developing psychiatric disorders. Progress in Neuro-Psychopharmacology and Biological Psychiatry. 2023. 126. 110783

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MISC (29)：

松﨑秀夫, 臼井紀好. 自閉スペクトラム症における酸化ストレス. 医学のあゆみ. 2024. 289. 4. 260-262
臼井紀好. 社会性行動の神経基盤及び分子メカニズムの研究. 解剖学雑誌. 2024. 99. 1. 35
Noriyoshi Usui, Miyuki Doi, Stefano Berto, Kiwamu Matsuoka, Rio Ishida, Koichiro Irie, Nanako Nakama, Hana Miyauchi, Yuuki Fujiwara, Takahira Yamauchi, et al. Copper-deficiency is associated with impairments in social behavior and oligodendrocyte development via mTOR signaling pathway. medRxiv. 2023
臼井紀好. モデルマウスを用いた自閉スペクトラム症の病態解析と新規診断法の開発. 脳と発達. 2023. 55. 173
臼井紀好. 自閉スペクトラム症の生物学的メカニズムの解明と早期診断法の開発. 日本生物学的精神医学会誌. 2022. 33. 4. 260

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Patents (27)：

酸化ストレスに起因する疾患の予防または治療剤
虚血性脳血管障害に伴う障害の予防又は治療剤
糖尿病の予防又は治療剤
脊髄損傷後の障害もしくは症状の予防又は治療剤
内臓不快感の予防又は治療剤

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Books (1)：

発達障がい -病態から支援まで-
朝倉書店 2022

Lectures and oral presentations (183)：

自閉スペクトラム症の病態形成における代謝異常の関与
(BPCNPNP2025合同年会 2025)
自閉スペクトラム症の病態形成メカニズムにおける代謝異常の関与
(第68回日本神経化学会大会 2025)
自閉スペクトラム症の病態形成メカニズムにおける代謝異常の機能解析
(第48回日本神経科学大会 2025)
遺伝子変異に着目した自閉スペクトラム症の病態形成メカニズムの解析
(第48回日本神経科学大会 2025)
精神刺激薬がマウスの社会性行動に与える影響についての検討
(第48回日本神経科学大会 2025)

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Education (2)：

2007 - 2012 The Graduate University for Advanced studies School of Life Science Department of Physiological Sciences
2002 - 2007 Nihon Univercity College of Bioresource Sciences Department of Applied Biological Sciences

Professional career (1)：

Ph.D. (The Graduate University for Advanced Studies)

Work history (6)：

2021/10 - 現在 Osaka University Graduate School of Medicine Associate Professor
2020/09 - 2021/09 Osaka University Graduate School of Medicine Assistant Professor
2018/03 - 2020/08 Osaka University Graduate School of Medicine Assistant Professor
2017/04 - 2018/02 University of Fukui Research Center for Child Mental Development Assistant Professor
2012/04 - 2017/03 University of Texas Southwestern Medical Center Postdoctoral Fellow

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Committee career (27)：

2025/03 - 現在日本解剖学会若手育成委員会委員
2025/03 - 現在日本解剖学会ダイバーシティ推進委員会委員
2024/07 - 現在日本生物学的精神医学会評議員
2024/03 - 現在日本神経化学会評議員
2023/12 - 現在日本脳科学会理事

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Awards (12)：

2023/11 - 大阪大学大阪大学賞 (若手教員部門)
2023/05 - 大阪大学全学選抜自主研究成果発表会優秀賞
2023/03 - The Japanese Association of Anatomists Encouragement Award
2022/01 - The Japanese Association of Anatomists Kinki Branch Excellent Presentation Award
2021/07 - The Japanese Society of Biological Psychiatry Young Investigator Award

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Association Membership(s) (10)：

日本生理学会 , 盛和スカラーズソサエティ , Japanese Society of Biological Psychiatry , The Japan Brain Science Society , The Japanese Association of Anatomists , 自閉症学研究会 , Society for Neuroscience , International Society for Neurochemistry , The Japanese Society for Neurochemistry , The Japan Neuroscience Society

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