NAKASHIMA TAKU

ナカシマタク | NAKASHIMA TAKU

Affiliation and department：
Homepage URL (1)： https://nrid.nii.ac.jp/ja/nrid/1000090643792/

Research field (1)： Respiratory medicine

Research keywords (2)： Pulmonary fibrosis, Interstitial lung diseases, bone marrow cells, tissue resident stem cells, lung cancer, lung injury , Bone marrow, Fibrosis, Pulmonary fibrosis, Interstitial pneumonia, Tissue resident stem cells, Lung cancer, Lung injury, Bone marrow transplantation

Research theme for competitive and other funds (9)：

2023 - 2024 肺線維症における口腔内微生物叢変容の意義
2024 - 骨髄細胞に潜在する質的障害が肺線維症に与える影響の解明
2020 - 2023 Selection of bone marrow ALDH bright cells for treatment of pulmonary fibrosis focusing on changes in bone marrow characteristics
2020 - 2021 腸内細菌叢の変化は肺線維症を悪化させるか
2017 - 2020 ALDH activity-guided detection of lung tissue stem cells and its therapeutic use for pulmonary fibrosis

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Papers (127)：

Tanahashi, Hiroki, Iwamoto, Hiroshi, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Masuda, Takeshi, Nakashima, Taku, Ohshimo, Shinichiro, Fujitaka, Kazunori, Hamada, Hironobu, et al. Lipocalin-2 as a prognostic marker in patients with acute exacerbation of idiopathic pulmonary fibrosis. RESPIRATORY RESEARCH. 2024. 25. 1
Miura, Shinichiro, Iwamoto, Hiroshi, Namba, Masashi, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, Horimasu, Yasushi, Masuda, Takeshi, Miyamoto, Shintaro, Nakashima, Taku, Ohshimo, Shinichiro, et al. High S100A9 level predicts poor survival, and the S100A9 inhibitor paquinimod is a candidate for treating idiopathic pulmonary fibrosis. BMJ OPEN RESPIRATORY RESEARCH. 2024. 11. 1
Shimoji, Kiyofumi, Nakashima, Taku, Masuda, Takeshi, Namba, Masashi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Mimae, Takahiro, Miyamoto, Shintaro, Iwamoto, Hiroshi, et al. Hypoxia-inducible factor 1a modulates interstitial pneumonia-mediated lung cancer progression. JOURNAL OF TRANSLATIONAL MEDICINE. 2023. 21. 1
Oda, Takashi, Iwamoto, Hiroshi, Takeno, Sachio, Kawasumi, Tomohiro, Takemoto, Kota, Nishida, Manabu, Chikuie, Nobuyuki, Horibe, Yuichiro, Yamaguchi, Kakuhiro, Sakamoto, Shinjiro, et al. Exhaled Nitric Oxide and Olfactory Dysfunction in Patients with Asthma: Association with Chronic Rhinosinusitis. MEDICINA-LITHUANIA. 2023. 59. 10
Yamada, Takahiro, Nakashima, Taku, Masuda, Takeshi, Sakamoto, Shinjiro, Yamaguchi, Kakuhiro, Horimasu, Yasushi, Miyamoto, Shintaro, Iwamoto, Hiroshi, Fujitaka, Kazunori, Hamada, Hironobu, et al. Intestinal overgrowth of Candida albicans exacerbates bleomycin-induced pulmonary fibrosis in mice with dysbiosis. JOURNAL OF PATHOLOGY. 2023. 261. 2. 227-237

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MISC (13)：

中尾聡志, 山口覚博, 鍵本篤志, 半田良憲, 坂本信二郎, 堀益靖, 益田武, 見前隆洋, 宮本真太郎, 中島拓, et al. Lower baseline levels of systemic soluble receptor for advanced glycation end products predict postoperative acute exacerbation of interstitial lung disease caused by lung cancer surgery. 日本呼吸器学会誌(Web). 2021. 10
中西雄, 益田武, 山口覚博, 坂本信二郎, 堀益靖, 見前隆洋, 中島拓, 宮本真太郎, 津谷康大, 岩本博志, et al. NLRとAGRを用いたNSCLCに対するimmune checkpoint inhibitorの効果予測因子の検討. 日本肺癌学会総会号. 2020. 61st
益田武, 中西雄, 山口覚博, 坂本信二郎, 堀益靖, 見前隆洋, 宮本真太郎, 中島拓, 津谷康大, 岩本博志, et al. Interstitial lung abnormalitiesの存在はPD-1/PD-L1阻害剤による肺障害に対するリスク因子となる. 日本肺癌学会総会号. 2019. 60th
中西雄, 益田武, 山口覚博, 坂本信二郎, 堀益靖, 見前隆洋, 中島拓, 宮本真太郎, 津谷康大, 岩本博志, et al. 複数のバイオマーカーを用いたNSCLCに対するimmune checkpoint inhibitorの効果予測因子の検討. 日本肺癌学会総会号. 2019. 60th
Hiroshi Iwamoto, Yasushi Horimasu, Taku Nakashima, Shinichiro Ohshimo, Nobuhisa Ishikawa, Kazunori Fujitaka, Yoshinori Haruta, Hiroshi Murai, Noboru Hattori, Witold Mazur, et al. Decreased circulatory receptor for advanced glycation end-products is associated with poorer survival in patients with idiopathic pulmonary fibrosis. EUROPEAN RESPIRATORY JOURNAL. 2014. 44

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Books (9)：

今日の診断指針第8版
医学書院 2018
間質性肺炎・肺線維症と類縁疾患
中山書店 2018
「間質性肺炎・肺線維症のトピックス」
科学評論社 2018
「ARDSのすべて」
科学評論社 2018
特発性間質性肺炎診断と治療の手引き
2016

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Lectures and oral presentations (207)：

非小細胞肺癌における免疫チェックポイント阻害剤に対する初期耐性の克服-PAI-1を標的とした治療方法の開発-
(第64回日本肺癌学会総会 2311)
イピリムマブ併用/非併用複合免疫療法の毒性中止例における臨床転帰の比較ー多施設共同後向き研究ー
(第64回日本肺癌学会総会 2311)
進展型小細胞肺癌の下垂体転移に対し薬物療法を行い病勢制御し得た1例
(第69回日本呼吸器中国・四国地方会 2023)
外科的肺切除が奏効した器質化肺炎合併壊死性肺炎の一例
(第69回日本呼吸器中国・四国地方会 2023)
Real worldにおけるイピリムマブ併用/非併用複合免疫療法におけるPD-L1 発現別の有効性・安全性の検討
(第64回日本肺癌学会学術集会 2023)

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Education (2)：

2003 - 2008 Hiroshima University Graduate School, Division of Medical Sciences
1995 - 2001 Hiroshima University Faculty of Medicine

Professional career (1)：

MD, PhD. (Hiroshima University)

Work history (11)：

2024/04 - 現在 Hiroshima University Molecular and Internal Medicine Lecturer
2024/04/01 - Graduate School of Biomedical and Health Sciences (Medicine) Dept. of Molecular and Internal Medicine Lecturer
2017/10 - 2024/03 Hiroshima University Hospital Respiratory Medicine Clinical Lecturer
2012/12 - 2024/03 Hiroshima University Hospital Hospital Research associate
2012/07/01 - 2012/11/30 Hiroshima University Hospital Research associate

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Awards (2)：

2009 - 広島大学広仁会第27回広仁会賞
2008/05 - American Thoracic Society ATS Travel Award Suppressor of cytokine signaling1 inhibits pulmonary inflammation and fibrosis

Association Membership(s) (4)：

日本呼吸器内視鏡学会 , 日本アレルギー学会 , 日本呼吸器学会 , 日本内科学会

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