Morise Jyoji

モリセジョウジ | Morise Jyoji

Affiliation and department：
Job title： Associate professor
Homepage URL (2)： http://oka-lab.hs.med.kyoto-u.ac.jp/index.html , http://oka-lab.hs.med.kyoto-u.ac.jp/index_en.html

Research field (1)： Functional biochemistry

Research keywords (2)：非硫酸化HNK-1糖鎖 , 腎機能障害

Research theme for competitive and other funds (3)：

2022 - 2025 Elucidation of the protection mechanism of renal function by nonsulfated HNK-1 carbohydrate and its development of a glycan marker for renal dysfunction
2019 - 2021 Role of N-glycans in lateral diffusion of AMPA-type glutamate receptor in neuronal plasma membrane
2017 - 2019 Regulation of neuronal plasticity through AMPA receptor association by characteristic N-glycans

Papers (14)：

Aoki K, Higashi K, Oda S, Manabe A, Maeda K, Morise J, Oka S, Inuki S, Ohno H, Oishi S, Nonaka M. Engineering a low-immunogenic mirror-image VHH against vascular endothelial growth factor. ACS Chemical Biology. 2024. 19. 1194-1205
Higashi K, Oda S, Fujii M, Nishida F, Matsumoto H, Morise J, Oka S, Nonaka M. Construction of a T7 phage random peptide library by combining seamless cloning with in vitro translation. Journal of Biochemistry. 2024. 175. 85-93
Kawade H, Morise J, Mishra SK, Tsujioka S, Oka S, Kizuka Y. Tissue-specific regulation of HNK-1 biosynthesis by bisecting GlcNAc. Molecules. 2021. 26. 5176
Morise J, Yamamoto S, Midorikawa R, Takamiya K, Nonaka M, Takematsu H, Oka S. Distinct cell surface expression patterns of N-glycosylation site mutants of AMPA-type glutamate receptor under the homo-oligomeric expression conditions. International Journal of Molecular Science. 2020. 21. 5101
Midorikawa R, Takakura D, Morise J, Wakazono Y, Kawasaki N, Oka S, Takamiya K. Monitoring the glycosylation of α-amino-3-hydroxy-5-methyl-4-isoxazole-propionate-type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N-glycosylation occupancy by molecular chaperones in mice. Journal of Neurochemistry. 2020. 153. 5. 567-585

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MISC (13)：

Morise J. Alternation of glycan expression by introducing B3GAT1 into the respiratory epithelium restricts viral infections. Trends in Glycoscience and Glycotechnology. 2023. 35. E101
森瀬譲二. 腎機能における非硫酸化HNK-1糖鎖の役割と腎障害に伴う発現変化. 腎臓内科. 2023. 18. 47-54
Morise J. Discovery of a novel congenital disorder of glycosylation and characterization of oral L-fucose supplementation therapy. Trends in Glycoscience and Glycotechnology. 2022. 34. E113
Kizuka Y, Morise J, Oka S. Enzyme assay of glucuronyltransferases for HNK-1 epitope (GlcAT-P, B3GAT1 and GlcAT-S, B3GAT2). Glycoscience Protocols (GlycoPODv2). 2021
Kizuka Y, Morise J, Oka S. Enzyme assay of sulfotransferase for HNK-1 epitope (HNK-1ST, CHST10). Glycoscience Protocols (GlycoPODv2). 2021

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Lectures and oral presentations (28)：

尿中非硫酸化HNK-1糖鎖の腎疾患マーカーとしての有用性に関する検討
(第63回日本臨床化学会年次学術集会 2023)
グルクロン酸転移酵素GlcAT-P触媒領域近傍へのリン酸化の機能的意義解析
(第69回生化学会近畿支部例会 2023)
aminopeptidase Nに発現する非硫酸化HNK-1糖鎖の機能的役割解析
(第69回生化学会近畿支部例会 2023)
尿中非硫酸化HNK-1糖鎖の腎機能との関連性に関する解析
(第41回日本糖質学会年会 2022)
腎機能に関連した非硫酸化HNK-1糖鎖の発現解析および腎機能障害マーカーへの展開
(第65回日本腎臓学会学術総会 2022)

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Professional career (2)：

Work history (3)：

2023/04 - 現在 Human Health Sciences, Graduate School of Medicine, Kyoto Universtiy Associate professor
2015/04 - 2023/03 Human Health Sciences, Graduate School of Medicine, Kyoto Universtiy Assistant professor
2014/04 - 2015/03 Department of Biological Chemistry, Human Health Sciences, Graduate School of Medicine, Kyoto University

Awards (2)：

Association Membership(s) (3)：

JAPAN SOCIETY OF CLINICAL CHEMISTRY , THE JAPANESE SOCIETY OF CARBOHYDRATE RESEARCH , THE JAPANESE BIOCHEMICAL SOCIETY

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