Research field (2):
Neuroscience - general
, Basic brain sciences
Research keywords (2):
脳・神経
, 神経科学
Research theme for competitive and other funds (12):
2024 - 2028 集団としての皮質シナプス機能を理解、操作するためのアプローチ構築
2024 - 2027 伝達物質放出部位ダイナミクスを軸としたシナプス可塑性の統一的理解
2020 - 2025 Nanoscale visualization and mechanstic understanding of presynaptic plasticity
2021 - 2024 Regulation of hippocampal mossy fiber synapses and its functional significance.
2019 - 2021 海馬苔状線維シナプス・局所神経回路のスクラップ&ビルド
2017 - 2020 哺乳類中枢シナプス伝達・短期可塑性メカニズムの解明
2017 - 2019 聴覚系シナプスのスクラップ&ビルドによる回路機能制御
2015 - 2018 軸索とシナプス前終末の生理学的研究
2015 - 2018 シナプス小胞解析のための蛍光プローブの適用
2014 - 2016 糖鎖によるシナプス前終末の機能修飾
2012 - 2015 単一シナプス前終末の光刺激法の開発
2012 - 2015 神経伝達物質放出における律速段階の解明
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Papers (55):
Himawari Hirai, Kohtarou Konno, Miwako Yamasaki, Masahiko Watanabe, Takeshi Sakaba, Yuki Hashimotodani. Distinct release properties of glutamate/GABA co-transmission serve as a frequency-dependent filtering of supramammillary inputs. eLife. 2024. 13. RP99711
Takafumi Miki, Yuji Okamoto, Miyuki Ueno-Umegai, Rio Toyofuku, Shun Hattori, Takeshi Sakaba. Single-vesicle imaging reveals actin-dependent spatial restriction of vesicles at the active zone, essential for sustained transmission. Proceedings of the National Academy of Sciences. 2024. 121. 43. e2402152121
Taichi Onishi, Kenzo Hirose, Takeshi Sakaba. Molecular tools to capture active neural circuits. Frontiers in Neural Circuits. 2024. 18
Kinetic analysis of transmitter release at hippocampal mossy fiber synapses
(FENS Satellite Symposium, Recent Advancements: Unraveling Synaptic Transmission In Hippocampal Mossy Fiber Synapses, ISTA, Austria 2024)
Electrophysiology of synaptic transmission (in Japanese)
(The 46th meeting of the Japanese Neuroscience Society 2023)
Synaptic vesicle pools at mammalian central synapses
(2021 Annual meeting of Korea Society for Brain and Neural Sciences (KSBNS) 2021)
Kinetics of transmitter release at hippocampal mossy fiber synapses
(Kinetics of transmitter release at hippocampal mossy fiber synapses 2019)
Comparison of the transmitter release properties between the calyx of Held synapse and mossy fiber-CA3 synapse
(Quantitaive aspects of membrane fuison and fission, Biopysical Society Thematic meetings 2019)