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J-GLOBAL ID：201201068306951227 Update date: Apr. 07, 2025

Tomotaka Oroguchi

オログチトモタカ | Tomotaka Oroguchi

Affiliation and department：
Job title： Assistant Professor/Senior Assistant Professor

Research field (1)： Bio-, chemical, and soft-matter physics

Research keywords (5)： X線溶液散乱 , 分子動力学シミュレーション , 蛋白質水和構造 , 蛋白質ダイナミクス , 生物物理、生体分子水和・ダイナミックス、X線ナノイメージング

Research theme for competitive and other funds (10)：

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Papers (54)：

Rintaro Inoue, HTomotaka Oroguchi, HR, Takashi Oda, Bela Farago, Anne Martel, Lionel Porcar, Mamoru Sato, Masaaki Sugiyama, ally contributed. Internal dynamics of multidomain protein as revealed by an optimized neutron spin echo measurement and all-atom molecular dynamics simulation. Physical Review Research. 2023. 5. 4. 043154
Amane Kobayashi, Yuki Takayama, Takeshi Hirakawa, Koji Okajima, Mao Oide, HTomotaka Oroguchi, HR, Yayoi Inui, Masaki Yamamoto, Sachihiro Matsunaga, et al. Common architectures in cyanobacteria Prochlorococcus cells visualized by X-ray diffraction imaging using X-ray free electron laser. Scientific Reports. 2021. 11. 1. 3877-3877
HTomotaka Oroguchi, HR, Mao Oide, Taiki Wakabayashi, Masayoshi Nakasako. Assessment of force field accuracy using cryogenic electron microscopy data of hyper-thermostable glutamate dehydrogenase. Journal of Physical Chemistry B. 2020. 124. 39. 8479-8494
Masayoshi Nakasako, Mao Oide, Yuki Takayama, HTomotaka Oroguchi, HR, Koji Okajima. Domain organization in plant blue-light receptor phototropin2 of arabidopsis thaliana studied by small-angle x-ray scattering. International journal of molecular sciences. 2020. 21. 18. 6638
Mao Oide, Takayuki Kato, HTomotaka Oroguchi, HR, Masayoshi Nakasako. Energy landscape of domain motion in glutamate dehydrogenase deduced from cryo-electron microscopy. FEBS Journal. 2020. 287. 16. 3472-3493

MISC (3)：

H苙口友隆, HR. 水素結合方向性における非共有結合対の影響: 分子動力学シミュレーションによる評価. アンサンブル. 2021. 23. 176-181
中迫雅由, H苙口友隆, HR, 関口優希, 小林周, 橋本早紀, 山本雅貴, 引間孝明, 米倉功治, 高山裕貴, et al. X線自由電子レーザーを用いた非結晶粒子のコヒーレントX線回折イメージング. 日本結晶学会誌. 2014. 55. 24-31
HTomotaka Oroguchi, HR, Mitsunori Ikeguchi, Mamoru Sato. Protein dynamics investigated by small-angle X-ray diffraction imaging. 日本結晶学会誌. 2013. 55. 24-31

Books (1)：

Lectures and oral presentations (56)：

Optimization of MD-derived conformational ensemble in information content space and its application to experimental X-ray solution scattering data
(TSRC Proten Dynamiccs Workshop 2023)
MDシミュレーションと溶液散乱実験による蛋白質構造揺らぎの可視化: ベイズ学習の適用に向けて
(情報計算化学生物学会2021年学会)
Protein structural fluctuations investigated by X-ray solution scattering and molecular dynamics simulation
(The 55<sup>th</sup> Annual Meeting of the Biophysical Society of Japan)
Protein conformational fluctuations and hydration structures investigated by the combination of MD simulations and X-ray experiments
(TSRC Protein Dynamics Workshop 2017)
MDシミュレーションと溶液X線小角散乱で探る蛋白質の構造揺らぎ
(第17回日本蛋白質科学会年会)

Education (6)：

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Professional career (1)：

Work history (3)：

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