Research theme for competitive and other funds (23):
2023 - 2027 Development of cocktail vaccines against poultry red mites using the recombinant turkey herpesvirus
2024 - 2027 Elucidation of the mechanism of tumorigenesis in bovine leukemia by comprehensive genomic analysis of proviral integration sites
2023 - 2026 The roles of polymorphism in Meq on the pathogenicity of Marek's disease virus and their application for the vaccine development
2022 - 2026 Construction of animal foamy virus vector and development of enzootic bovine leukosis vaccine
2020 - 2023 The search for the candidate molecule for the vaccine to control a wide range of ectoparasite species of chickens
2020 - 2023 血液脳関門を透過する新規DDSによる神経向性ウイルス感染の治療法開発
2019 - 2023 MHC クラスII DRB3*0902保有牛における牛白血病抵抗性機序
2018 - 2021 Development of a method to control poultry red mites using recombinant Marek's disease virus that secretes a vaccine antigen
2017 - 2020 Analysis of the molecular mechanism for the increase in the virulence of Marek's disease virus
2016 - 2019 Analysis of genetic polymorphism of poultry red mites in the world and search for candidate molecules of anti-mite vaccines
2016 - 2018 Comprehensive analysis of molecules expressed on the midgut of poultry red mites for the development of new anti-mite vaccines
2014 - 2017 Intramammary infusion of food-grade lactic acid bacteria (Bifidobacterium breve) on cellular and immuno-modulatory functions in mammary glands and therapeutic trials on bovine mastitis in dairy cows.
2014 - 2017 Influence of the immune status on the malignancy of canine histiocytic sarcoma
2014 - 2017 Studies on the molecular mechanisms for the increase in MDV virulence in the field
2012 - 2016 Defence mechanism against environmental chemicals in livestock animals
2011 - 2014 Studies on the immunoinhibitory mechanisms of Marek's disease virus and its application for adjuvant
2010 - 2014 Epidemiological and immunological analyzes of spread manner of bovine viral diarrhea virus in the herd
2009 - 2011 Identification and characterization of factors involved in the resistance to Marek' s disease in chickens and wild waterfowls
2008 - 2010 Studies on the molecular mechanisms for Marek's disease virus to increase its virulence in the field
2006 - 2008 Genetic analysis of drug resistant trypanosomes
2006 - 2007 抗糖脂質モノクローナル抗体のイヌ型抗体化とメラノーマ治療への応用
2006 - 2007 ダニの唾液由来免疫抑制因子を用いるダニ媒介性病原体の伝播阻止
2005 - 2007 Tick vaccine development by using tick testis-derived factors
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Papers (302):
Shunsuke Yamagami, Jumpei Sato, Yoshinosuke Motai, Naoya Maekawa, Tomohiro Okagawa, Satoru Konnai, Kazuhiko Ohashi, Shiro Murata. Genomic characteristics and distinctive genetic polymorphisms of Marek's disease virus strains circulating in Japan. The Journal of veterinary medical science. 2025
Maekawa N., Konnai S., Watari K., Takeuchi H., Nakanishi T., Tachibana T., Hosoya K., Kim S., Kinoshita R., Owaki R., et al. Development of caninized anti-CTLA-4 antibody as salvage combination therapy for anti-PD-L1 refractory tumors in dogs. Front Immunol. 2025. in press. in press
Fumiya Horio, Hikari Seo, Shwe Yee Win, Jumpei Sato, Yoshinosuke Motai, Shunsuke Yamagami, Takumi Sato, Eiji Ohishi, Naoya Maekawa, Tomohiro Okagawa, et al. Characterization of a lipocalin-like molecule from Dermanyssus gallinae as a potential vaccine antigen. Veterinary immunology and immunopathology. 2025. 283. 110921-110921
Ryo Owaki, Kenji Hosoya, Tatsuya Deguchi, Satoru Konnai, Naoya Maekawa, Tomohiro Okagawa, Hironobu Yasui, Sangho Kim, Takafumi Sunaga, Masahiro Okumura. Enhancement of radio-sensitivity by inhibition of Janus kinase signaling with oclacitinib in canine tumor cell lines. Molecular therapy. Oncology. 2025. 33. 1. 200946-200946
Joao BC, Parizi LF, Zhou J., Konnai S., Termignoni C., da Silva Vaz I J. Host Skin during Tick Infestation: Unearthing the Local Immunity to Lead an Anti-Tick Vaccine. Acta Scientiae Veterinariae. 2025. 53. 1982
もたい吉之介, 村田史郎, 村田史郎, 佐藤純平, 山上竣裕, SHWE Win Yee, 堀尾文彌, 前川直也, 岡川朋弘, 今内覚, et al. Effect of polymorphisms in the meq gene of Marek’s disease virus distributed in Japan on the pathogenicity and transcriptional regulation. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2024. 71st
佐藤純平, 村田史郎, 村田史郎, もたい吉之介, 山上竣裕, 堀尾文彌, SHWE Win Yee, 前川直也, 岡川朋弘, 今内覚, et al. Effect of polymorphisms in the basic region of Meq protein of Marek’s disease, an avian oncogenic herpesvirus, on virulence. 日本ウイルス学会学術集会プログラム・予稿集(Web). 2024. 71st
THE JAPANESE SOCIETY FOR VIROLOGY
, 大動物臨床研究会
, JAPANESE SOCIETY FOR CLINICAL INFECTIOUS DISEASE IN FARM ANIMALS
, 動物サイトカイン研究会
, 日本獣医寄生虫学会
, 動物用ワクチン-バイオ医薬品研究会
, 北海道獣医師会
, JAPAN VETERINARY MEDICAL ASSOCIATION
, JAPANESE SOCIETY OF VETERINARY SCIENCE