Shinichi Yamamoto

ヤマモトシンイチ | Shinichi Yamamoto

Affiliation and department：
Job title： Research Collaborator
Other affiliations (1)：

Juntendo University Center for Immune Therapeutics and Diagnosis, Advanced Research Institute for Health Science Assistant professor

Research field (3)： Hematology and oncology , Neuroscience - general , Immunology

Research keywords (5)：免疫寛容 , 腫瘍血液疾患 , 制御性T細胞(Treg) , グリア細胞ミクログリアアストロサイト , 中枢神経疾患

Research theme for competitive and other funds (6)：

2021 - 2024 Acquisition mechanism of brain-specific properties for regulatory T cells in central nervous system diseases
2015 - 2016 高齢者脂肪髄中の白血病細胞の脂肪酸代謝-転写メカニズムと代謝制御マーカーの探索
2014 - 2015 ラットの顔面神経傷害時における増殖性ミクログリアの免疫機能解析
2013 - 2014 神経傷害時におけるミクログリアの免疫機能発現調節に関する研究
2013 - 2014 Involvement of MAP kinase cascade in M-CSF-triggered microglial proliferation in transected rat facial nucleus

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Papers (12)：

Shinichi Yamamoto, Ako Matsui, Masaki Ohyagi, Chie Kikutake, Yoshihiro Harada, Mana Iizuka-Koga, Mikita Suyama, Akihiko Yoshimura, Minako Ito. In Vitro Generation of Brain Regulatory T Cells by Co-culturing With Astrocytes. Frontiers in Immunology. 2022. 13. 960036-960036
Sekihara K, Saitoh K, Han L, Ciurea S, Yamamoto S, Kikkawa M, Kazuno S, Taka H, Kaga N, Arai H, et al. Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1. Oncotarget. 2017. 8. 21. 34552-34564
Tabe Y, Yamamoto S, Saitoh K, Sekihara K, Monma N, Ikeo K, Mogushi K, Shikami M, Ruvolo V, Ishizawa J, et al. Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells. Cancer Research. 2017. 77. 6. 1453-1464
Tabe Y, Hatanaka Y, Nakashiro M, Sekihara K, Yamamoto S, Matsushita H, Kazuno S, Fujimura T, Ikegami T, Nakanaga K, et al. Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells. International Journal of Radiation Bioly. 2016. 92. 1. 24-34
Harada M, Benito J, Yamamoto S, Kaur S, Arslan D, Ramirez S, Jacamo R, Platanias L, Matsushita H, Fujimura T, et al. The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression. Oncotarget. 2015. 6. 35. 37930-47

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MISC (3)：

伊藤美菜子, 山本伸一, 大谷木正貴, 吉村昭彦. 【神経免疫メカニズムと疾患神経系と免疫系を結ぶ分子機構の解明からバイオマーカー・治療標的の探索まで】(第1章)神経免疫のメカニズム神経炎症の誘導と制御(リンパ球) 制御性T細胞による中枢神経炎症制御. 実験医学. 2021. 39. 15. 2342-2347
伊藤美菜子, 大谷木正貴, 山本伸一, 吉村昭彦. Regulatory T cells and IL-33. 臨床免疫・アレルギー科. 2020. 74. 5. 470-476
伊藤美菜子, 山本伸一, 吉村昭彦. Tissue regulatory T cells and tissue repair. 臨床免疫・アレルギー科. 2019. 72. 6. 575-582

Books (2)：

生物の寿命延長 : 老化・長寿命の基盤研究最前線
エヌ・ティー・エス 2022 ISBN:9784860437732
神経免疫 : メカニズムと疾患 : 神経系と免疫系を結ぶ分子機構の解明からバイオマーカー・治療標的の探索まで
羊土社 2021 ISBN:9784758103978

Education (3)：

Professional career (1)：

Awards (2)：

2023/07 - Korean Association of Immunologist KAI International Meeting 2023 Travel Awards In vitro generation of brain regulatory T cells by co-culturing with astrocytes
2023/07 - The 44th Annual Meeting of the Japanese Society of Inflammation and Regeneration Best Presentation Award In vitro generation of brain regulatory T cells by co-culturing with astrocytes

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