Rchr
J-GLOBAL ID:201301005908668084
Update date: Nov. 17, 2024 Shinichi Yamamoto
ヤマモト シンイチ | Shinichi Yamamoto
Affiliation and department: Job title:
Assistant Research Engineer
Research field (4):
Respiratory medicine
, Hematology and oncology
, Neuroscience - general
, Immunology
Research keywords (6):
エクソソーム
, 免疫寛容
, がん
, Treg
, グリア細胞
, 中枢神経疾患
Research theme for competitive and other funds (6): - 2021 - 2024 Acquisition mechanism of brain-specific properties for regulatory T cells in central nervous system diseases
- 2015 - 2016 高齢者脂肪髄中の白血病細胞の脂肪酸代謝-転写メカニズムと代謝制御マーカーの探索
- 2014 - 2015 ラットの顔面神経傷害時における増殖性ミクログリアの免疫機能解析
- 2013 - 2014 神経傷害時におけるミクログリアの免疫機能発現調節に関する研究
- 2013 - 2014 Involvement of MAP kinase cascade in M-CSF-triggered microglial proliferation in transected rat facial nucleus
- 2012 - 2013 Signaling mechanism by which microglial proliferate by M-CSF upregulated in the transected rat facial nucleus
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Papers (12): -
Shinichi Yamamoto, Ako Matsui, Masaki Ohyagi, Chie Kikutake, Yoshihiro Harada, Mana Iizuka-Koga, Mikita Suyama, Akihiko Yoshimura, Minako Ito. In Vitro Generation of Brain Regulatory T Cells by Co-culturing With Astrocytes. Frontiers in Immunology. 2022. 13. 960036-960036
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Sekihara K, Saitoh K, Han L, Ciurea S, Yamamoto S, Kikkawa M, Kazuno S, Taka H, Kaga N, Arai H, et al. Targeting mantle cell lymphoma metabolism and survival through simultaneous blockade of mTOR and nuclear transporter exportin-1. Oncotarget. 2017. 8. 21. 34552-34564
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Tabe Y, Yamamoto S, Saitoh K, Sekihara K, Monma N, Ikeo K, Mogushi K, Shikami M, Ruvolo V, Ishizawa J, et al. Bone Marrow Adipocytes Facilitate Fatty Acid Oxidation Activating AMPK and a Transcriptional Network Supporting Survival of Acute Monocytic Leukemia Cells. Cancer Research. 2017. 77. 6. 1453-1464
- Tabe Y, Hatanaka Y, Nakashiro M, Sekihara K, Yamamoto S, Matsushita H, Kazuno S, Fujimura T, Ikegami T, Nakanaga K, et al. Integrative genomic and proteomic analyses identifies glycerol-3-phosphate acyltransferase as a target of low-dose ionizing radiation in EBV infected-B cells. International Journal of Radiation Bioly. 2016. 92. 1. 24-34
- Harada M, Benito J, Yamamoto S, Kaur S, Arslan D, Ramirez S, Jacamo R, Platanias L, Matsushita H, Fujimura T, et al. The novel combination of dual mTOR inhibitor AZD2014 and pan-PIM inhibitor AZD1208 inhibits growth in acute myeloid leukemia via HSF pathway suppression. Oncotarget. 2015. 6. 35. 37930-47
more... MISC (5): -
伊藤 美菜子, 山本 伸一, 大谷木 正貴, 吉村 昭彦. 【神経免疫 メカニズムと疾患 神経系と免疫系を結ぶ分子機構の解明からバイオマーカー・治療標的の探索まで】(第1章)神経免疫のメカニズム 神経炎症の誘導と制御(リンパ球) 制御性T細胞による中枢神経炎症制御. 実験医学. 2021. 39. 15. 2342-2347
- 伊藤美菜子, 大谷木正貴, 山本伸一, 吉村昭彦. Regulatory T cells and IL-33. 臨床免疫・アレルギー科. 2020. 74. 5. 470-476
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伊藤美菜子, 山本伸一, 吉村昭彦. Tissue regulatory T cells and tissue repair. 臨床免疫・アレルギー科. 2019. 72. 6. 575-582
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Yoko Tabe, Shinichi Yamamoto, Mika Kikkawa, Hikari Taka, Kaoru Mogushi, Hiromichi Mastushita, Takashi Miida, Michael Andreeff, Paul A. Spagnuolo, Marina Konopleva. Novel FAO Inhibitor Avocatin B Induces Apoptosis of Acute Monocytic Leukemia Cells in Adipocyte Co-Culture System Via ER Stress and ATF4 Activation. BLOOD. 2015. 126. 23
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Yoko Tabe, Yasuhito Hatanaka, Mayumi Nakashiro, Kazumasa Sekihara, Shinichi Yamamoto, Hiromichi Matsushita, Saiko Kazuno, Michael Andreeff, Marina Konopleva, Keisuke Sasai, et al. Low-Dose Ionizing Radiation Modulates Expression of Gpam in Immortalized EBV Infected B Cells through miRNA Network. BLOOD. 2015. 126. 23
Books (2): - 生物の寿命延長 : 老化・長寿命の基盤研究最前線
エヌ・ティー・エス 2022 ISBN:9784860437732
- 神経免疫 : メカニズムと疾患 : 神経系と免疫系を結ぶ分子機構の解明からバイオマーカー・治療標的の探索まで
羊土社 2021 ISBN:9784758103978
Professional career (1): - Doctor (Engineering) (Soka University)
Awards (2): - 2023/07 - Korean Association of Immunologist KAI International Meeting 2023 Travel Awards In vitro generation of brain regulatory T cells by co-culturing with astrocytes
- 2023/07 - The 44th Annual Meeting of the Japanese Society of Inflammation and Regeneration Best Presentation Award In vitro generation of brain regulatory T cells by co-culturing with astrocytes
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