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J-GLOBAL ID：201301010993275375 Update date: Apr. 20, 2025

Hisashi Wada

ワダヒサシ | Hisashi Wada

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Affiliation and department：
Job title： Specially Appointed Professor
Other affiliations (1)：

臨床腫瘍免疫学特任教授

Homepage URL (1)： http://www.climm.med.osaka-u.ac.jp/

Research field (3)： Tumor diagnostics and therapeutics , Tumor biology , General surgery, pediatric surgery

Research keywords (3)：免疫 , T細胞 , 寛容

Research theme for competitive and other funds (5)：

2022 - 2025 Impact of tumor-associated B cells in esophageal cancer
2022 - 2025 尿路性器癌における全身循環細菌叢及び細菌関連代謝が構築する癌局所免疫状態の解明
2019 - 2022 Development of cancer immunotherapy for urothelial carcinoma targeting tissue infiltrating regulatory T cells
2019 - 2022 Attempt of segmentation of positive / negative factor and absolute evaluation of intra-tumor immunity
1993 - 1993 宿主T細胞数制御による免疫寛容の誘導

Papers (144)：

Koichi Jinushi, Takuro Saito, Koji Kurose, Susumu Suzuki, Takashi Kojima, Taishi Takahara, Tomoki Makino, Tetsuya Ogawa, Hiroyoshi Nishikawa, Kazuhiro Kakimi, et al. Phase I study on neoadjuvant combination immunotherapy with mogamulizumab and nivolumab for solid tumors. Journal for immunotherapy of cancer. 2025. 13. 4
MARI TONE, TOMOMI ISONO, YOKO YAMAMOTO, YOSHITO TAKEDA, YASUSHI SHINTANI, ATSUSHI KUMANOGOH, HISASHI WADA, KOTA IWAHORI. Peripheral CD4⁺T Cells Predict T Cell Immunity in Lung Tissues of Non-small Cell Lung Cancer Patients. Anticancer Research. 2025. 45. 3. 909-920
Akinaru Yamamoto, Atsunari Kawashima, Toshihiro Uemura, Kosuke Nakano, Makoto Matsushita, Yu Ishizuya, Kentaro Jingushi, Hiroaki Hase, Kotoe Katayama, Rui Yamaguchi, et al. A novel mouse model of upper tract urothelial carcinoma highlights the impact of dietary intervention on gut microbiota and carcinogenesis prevention despite carcinogen exposure. International journal of cancer. 2024
Toshihiro Uemura, Atsunari Kawashima, Kentaro Jingushi, Daisuke Motooka, Takuro Saito, Nesrine Sassi, Yuki Horibe, Akinaru Yamamoto, Yutong Liu, Masaru Tani, et al. Bacterial information in serum extracellular vesicles reflects the inflammation of adherent perinephric fat. Cancer science. 2024
的羽大二朗, 野田剛広, 小林省吾, 佐々木一樹, 岩上佳史, 山田大作, 富丸慶人, 高橋秀典, 和田尚, 土岐祐一郎, et al. HCCにおいて腫瘍血管内皮細胞は腫瘍関連マクロファージのM2分極を促進する(Tumor vascular endothelial cells are associated with tumor-associated macrophage polarization to M2 in HCC). 日本癌学会総会記事. 2024. 83回. P-3174

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MISC (210)：

磯野友美, 岩堀幸太, 梁川雅弘, 福井絵里子, 木村亨, 狩野孝, 大瀬尚子, 舟木壮一郎, 和田尚, 新谷康. 間質性肺疾患合併非小細胞肺癌におけるT細胞免疫の検討. 日本呼吸器外科学会雑誌. 2023. 37. 3. P49-1
藤川馨, 西塔拓郎, 江口英利, 土岐祐一郎, 和田尚. Helicobacter pylori除菌による胃癌予後改善効果の検討. 日本がん免疫学会総会プログラム・抄録集. 2023. 27回. 81-81
加島佳奈, 西塔拓郎, 鵜澤成一, 和田尚. 口腔扁平上皮癌における細菌叢と腫瘍内免疫プロファイル. 日本がん免疫学会総会プログラム・抄録集. 2023. 27回. 85-85
高橋健太, 西塔拓郎, 百瀬洸太, 山下公太郎, 田中晃司, 山本和義, 牧野知紀, 高橋剛, 黒川幸典, 江口英利, et al. 胃癌ニボルマブ治療におけるirAEと予後の関連性. 日本がん免疫学会総会プログラム・抄録集. 2023. 27回. 117-117
住本知子, 牧野知紀, 百瀬洸太, 山下公太郎, 西塔拓郎, 田中晃司, 山本和義, 高橋剛, 黒川幸典, 土岐祐一郎, et al. 当院における切除不能進行・再発食道扁平上皮癌Nivolumab治療におけるirAEと予後の関係. 日本がん免疫学会総会プログラム・抄録集. 2023. 27回. 158-158

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Professional career (1)：

医学博士 (大阪大学)

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