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J-GLOBAL ID:201301023352826945   Update date: Oct. 31, 2024

Moro Kazuyo

モロ カズヨ | Moro Kazuyo
Affiliation and department:
Job title: Professor
Other affiliations (2):
Homepage URL  (1): https://morolab.jp/
Research field  (1): Immunology
Research keywords  (3): アレルギー性疾患 ,  ILC2 ,  寄生虫感染
Research theme for competitive and other funds  (14):
  • 2022 - 2025 Novel therapeutic strategy for refractory asthma using immunophenotyping
  • 2021 - 2023 The insight of the synergy between novel innate lymphoid cells and sex hormone homeostasis in PCOS
  • 2018 - 2023 Role of ILC2 in idiopathic interstitial pneumonia
  • 2016 - 2019 Role of innate lymphoid cells in adipose tissue homeostasis
  • 2016 - 2018 Role of ILC2 in the formation of maternal allergic inflammation and allergic susceptibility of the offspring
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Papers (94):
  • 福嶋 優希, 古賀 諭, 茂呂 和世. 【ヒト疾患と免疫細胞サブセット 解像度をあげて見えてきた病態を規定する疾患のキープレーヤーと治療戦略】(第1章)自然免疫系 ヒトILC2の多様性と機能制御 疾患への関与と治療標的としての可能性. 実験医学. 2024. 42. 12. 1840-1847
  • Sho Tabata, Keita Matsuda, Shou Soeda, Kenshiro Nagai, Yoshihiro Izumi, Masatomo Takahashi, Yasutaka Motomura, Ayaka Ichikawa Nagasato, Kazuyo Moro, Takeshi Bamba, et al. NFκB dynamics-dependent epigenetic changes modulate inflammatory gene expression and induce cellular senescence. The FEBS Journal. 2024
  • Mai Yamagishi, Kaede Miyata, Takashi Kamatani, Hiroki Kabata, Rie Baba, Yumiko Tanaka, Nobutake Suzuki, Masako Matsusaka, Yasutaka Motomura, Tsuyoshi Kiniwa, et al. Quantitative live-cell imaging of secretion activity reveals dynamic immune responses. iScience. 2024. 27. 6. 109840-109840
  • Natsuko Otaki, Yasutaka Motomura, Tommy Terooatea, S Thomas Kelly, Miho Mochizuki, Natsuki Takeno, Shigeo Koyasu, Miu Tamamitsu, Fuminori Sugihara, Junichi Kikuta, et al. Activation of ILC2s through constitutive IFNγ signaling reduction leads to spontaneous pulmonary fibrosis. Nature communications. 2023. 14. 1. 8120-8120
  • Yumiko Tanaka, Mai Yamagishi, Yasutaka Motomura, Takashi Kamatani, Yusuke Oguchi, Nobutake Suzuki, Tsuyoshi Kiniwa, Hiroki Kabata, Misato Irie, Tatsuhiko Tsunoda, et al. Time-dependent cell-state selection identifies transiently expressed genes regulating ILC2 activation. Communications Biology. 2023. 6. 1
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MISC (50):
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Professional career (2):
  • Ph. D. (Keio University)
  • D.D.S (Nihon University)
Work history (8):
  • 2019/04 - 現在 大阪大学医学系研究科 生体防御学教室 教授
  • 2019 - 現在 大阪大学大学院生命機能研究科 教授
  • 2019 - 現在 大阪大学免疫学フロンティア研究センター 免疫・アレルギー 教授
  • 2015/09 - 現在 理化学研究所生命医科学研究センター 自然免疫システム研究チーム チームリーダー
  • 2016/04 - 2019/03 横浜市立大学大学院生命医科学研究科 免疫生物学教室 大学院客員教授
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