Hirose Takuo

ヒロセタクオ | Hirose Takuo

Research field (11)： Pharmacology , Tumor biology , Cell biology , Developmental biology , Molecular biology , Neuroscience - general , Metabolism and endocrinology , Healthcare management, medical sociology , Nephrology , Clinical pharmacy , Physiology

Research keywords (8)： Renin angiotensin aldosterone system , Fibrosis , Hypertension , Kidney , Endocrinology and Metabolism , Peptides , (Pro)renin receptor , Ohasama study

Research theme for competitive and other funds (7)：

2023 - 2026 (Pro)renin receptor and V-ATPase in renal fibrosis
2020 - 2023 (Pro)renin receptor and renal fibrosis
2019 - 2022 Renal interstitial fibrosis in renal venous congestion
2019 - 2021 Pathophysiological connections between muscle and kidney
2015 - 2018 (プロ)レニン受容体の脳神経障害における役割と作用機序の解明

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Papers (118)：

Maya Toyama, Michihiro Satoh, Shingo Nakayama, Hideaki Hashimoto, Tomoko Muroya, Takahisa Murakami, Takuo Hirose, Taku Obara, Naoki Nakaya, Takefumi Mori, et al. Combined effects of blood pressure and glucose status on the risk of chronic kidney disease. Hypertension research : official journal of the Japanese Society of Hypertension. 2024
Fumihiko Watanabe, Shigemitsu Sato, Takuo Hirose, Moe Endo, Akari Endo, Hiroki Ito, Koji Ohba, Takefumi Mori, Kazuhiro Takahashi. NRIP1 regulates cell proliferation in lung adenocarcinoma cells. The Journal of Biochemistry. 2024
Megumi Tsubota-Utsugi, Michihiro Satoh, Jun Watanabe, Jun Takebayashi, Tomoyuki Oki, Yukako Tatsumi, Kei Asayama, Masahiro Kikuya, Takahisa Murakami, Takuo Hirose, et al. Association between an Antioxidant-Rich Japanese Diet and Chronic Kidney Disease: The Ohasama Study. Journal of atherosclerosis and thrombosis. 2023
Hiroki Ito, Takuo Hirose, Shigemitsu Sato, Chika Takahashi, Risa Ishikawa, Akari Endo, Ayaka Kamada, Ikuko Oba-Yabana, Tomoyoshi Kimura, Kazuhiro Murakami, et al. Pericyte detachment and renal congestion involve interstitial injury and fibrosis in Dahl salt-sensitive rats and humans with heart failure. Hypertension research : official journal of the Japanese Society of Hypertension. 2023
Go Anan, Takuo Hirose, Daisuke Kikuchi. Reply to Palle Osther’s Words of Wisdom re: Inhibition of Sodium-Glucose Cotransporter 2 Suppresses Renal Stone Formation. Eur Urol. In press. https://doi.org/10.1016/j.eururo.2023.03.009. European Urology. 2023

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MISC (161)：

末永司, 佐藤倫広, 村上任尚, 廣瀬卓男, 中山晋吾, 小原拓, 森建文, 今井潤, 大久保孝義, 目時弘仁. 収縮期・拡張期血圧を用いた詳細血圧分類と慢性腎臓病発症リスクの関連. 日本循環器病予防学会誌. 2023. 58. 2. 157-157
坪田恵, 佐藤倫広, 辰巳友佳子, 浅山敬, 菊谷昌浩, 村上任尚, 廣瀬卓男, 目時弘仁, 寳澤篤, 大久保孝義. 食事における抗酸化力と慢性腎臓病発症との関連大迫研究. 日本循環器病予防学会誌. 2023. 58. 2. 158-158
佐藤倫広, 吉田智哉, 目時弘仁, 村上任尚, 辰巳友佳子, 廣瀬卓男, 高畠恭介, 坪田恵, 原梓, 野村恭子, et al. 家庭血圧に基づく白衣効果の長期再現性大迫研究. Journal of Epidemiology. 2023. 33. Suppl.1. 126-126
廣瀬卓男, 廣瀬卓男, 伊藤大樹, 伊藤大樹, 遠藤明里, 遠藤明里, 加藤季子, 石川里紗, 佐藤峻行, 高橋知香, et al. 腎うっ血に伴う腎間質線維化に対するマイオカイン・アイリシンの保護効果. 日本内分泌学会雑誌. 2022. 98. 1
阿南剛, 廣瀬卓男, 菊池大輔, 高橋知香, 山越聖子, 佐藤信, 森建文, 森建文. 腎結石形成に対するSGLT2阻害薬の抑制効果:新規尿路結石治療薬の可能性. 日本尿路結石症学会誌. 2021. 20. 2

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Education (2)：

2004 - 2009 Tohoku Univesity Graduate School of Pharmaceutical Sciences Department of Clinival Pharmacology
2000 - 2004 Tohoku University Faculty of Pharmaceutical Sciences

Professional career (1)：

Doctor Philosophy (Pharmaceutical Health Care and Science) (Tohoku University)

Work history (12)：

2024/04 - 現在 Tohoku Medical and Pharmaceutical University Division of Integrative Renal Replacement Therapy Associate professor
2020/04 - 2024/03 Tohoku Medical and Pharmaceutical University Division of Integrative Renal Replacement Therapy Adjunct Lecturer
2020/04 - 2024/03 Tohoku University Graduate School of Medicine Department of Endocrinology and Applied Medical Science Assistant professor
2017/09 - 2020/03 Tohoku Medical and Pharmaceutical University Division of Nephrology and Endocrinology
2017/04 - 2020/03 Tohoku University Graduate School of Medicine Division of Nephrology, Endocrinology and Vascular Medicine Adjunct Lecturer

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Awards (4)：

2021/04 - 日本内分泌学会研究奨励賞組織の発生と障害における(プロ)レニン受容体の機能解析
2021/01 - 東北医学会奨学賞
2015/04 - THE JAPAN ENDOCRINE SOCIETY Young Investigator Award
2014/03 - Gordon Research Conference Angiotensin Young Investigator Award

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