Yoshikuni Goto

ゴトウヨシクニ | Yoshikuni Goto

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/90455345.ja.html

Research field (3)： Pathobiochemistry , Pharmaceuticals - health and biochemistry , Applied biochemistry

Research keywords (14)：エキソソーム , セロトニン , 不安障害 , アミノペプチダーゼ , 血圧調節 , インターフェロン , LPS , 分泌 , 貪食 , マクロファージ , リポ多糖 , 一酸化窒素 , 一塩基多型 , 基質特異性

Research theme for competitive and other funds (12)：

2022 - 2025 MHCクラスI抗原提示の機能不全が惹起する脳内セロトニン過剰疾患「不安障害」
2019 - 2022 Dysfunction of ERAP1 induces anxiety disorder via excess serotonin synthesis
2016 - 2019 Mechanism of mucosal immunity activation by exosome
2016 - 2019 Roles of ER aminopeptidase 1 in inflammation of Behcet's disease
2015 - 2017 Role of ERAP1 in the pathogenesis of mental disorders

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Papers (29)：

Yuko Ogawa, Yuri Miura, Mamoru Ikemoto, Atsushi Ohnishi, Yoshikuni Goto, Kazuma Aoki, Yuki Motokurumada, Yoshihiro Akimoto, Tamao Endo, Masafumi Tsujimoto, et al. Distinguishing two distinct types of salivary extracellular vesicles: a potential tool for understanding their pathophysiological roles. Frontiers in molecular biosciences. 2024. 11. 1278955-1278955
Rena Shiraishi, Satomi Morita, Yoshikuni Goto, Yasushi Mizoguchi, Wataru Nakamura, Takahiro J. Nakamura. Diurnal variations of triglyceride accumulation in mouse and bovine adipocyte-derived cell lines. Animal Science Journal. 2022. 93. 1. e13802
Yuko Ogawa, Yoshihiro Akimoto, Mamoru Ikemoto, Yoshikuni Goto, Anna Ishikawa, Sakura Ohta, Yumi Takase, Hayato Kawakami, Masafumi Tsujimoto, Ryohei Yanoshita. Stability of human salivary extracellular vesicles containing dipeptidyl peptidase IV under simulated gastrointestinal tract conditions. Biochemistry and biophysics reports. 2021. 27. 101034-101034
Masafumi Tsujimoto, Kazuma Aoki, Yoshikuni Goto, Atsushi Ohnishi. Molecular and functional diversity of the oxytocinase subfamily of M1 aminopeptidases. Journal of biochemistry. 2021. 169. 4. 409-420
Yoshikuni Goto, Takahiro J Nakamura, Kenji Ogawa, Akira Hattori, Masafumi Tsujimoto. Reciprocal Expression Patterns of Placental Leucine Aminopeptidase/Insulin-Regulated Aminopeptidase and Vasopressin in the Murine Brain. Frontiers in molecular biosciences. 2020. 7. 168-168

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MISC (49)：

後藤芳邦, 石毛奈桜, 野元裕, 辻本雅文, 中西雅之. Trypanosoma bruceiのVSGと宿主マクロファージの自然免疫関連分子間の相互作用. 日本寄生虫学会大会プログラム・抄録集. 2024. 93rd
小川裕子, 三浦ゆり, 後藤芳邦, 池本守, 秋元義弘, 遠藤玉夫, 矢ノ下良平. LPS-binding proteins in human salivary extracellular vesicles regulate the activation of macrophages. 日本薬学会年会要旨集(Web). 2023. 143rd
後藤芳邦, 野元裕, 辻本雅文, 中西雅之. Avoidance of host innate immunity by variant surface glycoprotein in Trypanosoma brucei. 日本寄生虫学会大会プログラム・抄録集. 2022. 91st
石毛奈桜, 後藤芳邦, 野元裕, 辻本雅文, 中西雅之. Molecular mechanism of mammalian host innate immune evasion of Trypanosoma brucei. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
平井杏奈, 鈴木優香, 中村孝博, 小川健司, 服部明, 辻本雅文, 後藤芳邦. Dysfuction of ER-aminopeptidase 1 induce serotonin-dependent anxiety. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th

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Education (1)：

2004 - 2007 Tokyo University of Agriculture and Technology United Graduate School of Agricultural Science Department of Biochemistry and Biotechnology

Professional career (1)：

Work history (4)：

Awards (1)：

2010/08 - 病態プロテアーゼ学会第14回日本病態プロテアーゼ学会学術集会学会奨励賞マクロファージにおける脂肪細胞由来ロイシンアミノペプチダーゼの分泌機構

Association Membership(s) (4)：

日本分子生物学会 , THE JAPANESE BIOCHEMICAL SOCIETY , 日本寄生虫学会 , 日本薬学会

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