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J-GLOBAL ID:201301046306234979   Update date: Apr. 09, 2025

Tomizawa Shinichi

トミザワシンイチ | Tomizawa Shinichi
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Affiliation and department:
Job title: Assistant Professor
Homepage URL  (1): http://www-user.yokohama-cu.ac.jp/~finemorp/
Research field  (4): Genetics ,  Developmental biology ,  Anatomy ,  Biological, health, and medical informatics
Research keywords  (6): Histology ,  Anatomy ,  Molecular biology ,  Stem cells ,  Germ cells ,  Epigenetics
Research theme for competitive and other funds  (15):
  • 2025 - 2028 Translational regulation of spermatogonial stem cell differentiation and subpopulation maintenance
  • 2024 - 2028 DNA methylation establishment in human male germ cells
  • 2025 - 2027 Epicode for germ cell priming
  • 2023 - 2026 Differentiation of stem cell subpopulation for spermatogenesis
  • 2020 - 2023 Molecular basis of infertility associated with epigenome abnormality
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Papers (26):
  • Kazushige Kuroha*, Ivana Dočkal*, Uroš Radović, Kuniko Nakajima, Ikue Hoshi, Shion Matsuda, Noriko Kojitani, Kazuyuki Ohbo, Shin-ichi Tomizawa. Abnormal H3K27me3 underlies degenerative spermatogonial stem cells in cryptorchid testis. Development. 2025. 152. 2. dev.204239
  • Michio Ono, Kuniko Nakajima, Shin-ichi Tomizawa, Takayuki Shirakawa, Ippei Okada, Hirotomo Saitsu, Naomichi Matsumoto, Kazuyuki Ohbo. Spatial and temporal expression analysis of BMP signal modifiers, Smoc1 and Smoc2, from postnatal to adult developmental stages in the mouse testis. Gene Expression Patterns. 2024. 119383
  • Shin-ichi Tomizawa, Rachel Fellows, Michio Ono, Kazushige Kuroha, Ivana Dočkal, Yuki Kobayashi, Keisuke Minamizawa, Koji Natsume, Kuniko Nakajima, Ikue Hoshi, et al. The non-canonical bivalent gene Wfdc15a controls spermatogenic protease and immune homeostasis. Development. 2024. 151. 18. dev202834
  • Shin-ichi Tomizawa*, Kazushige Kuroha*, Michio Ono, Kuniko Nakajima, Kazuyuki Ohbo. A behind-the-scenes role of BDNF in the survival and differentiation of spermatogonia. Asian Journal of Andrology. 2024. 26. 1-7
  • Florence Naillat, Heba Saadeh, Joanna Nowacka-Woszuk, Lenka Gahurova, Fatima Santos, Shin-ichi Tomizawa, Gavin Kelsey. Oxygen concentration affects de novo DNA methylation and transcription in in vitro cultured oocytes. Clinical Epigenetics. 2021. 13. 132
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MISC (19):
  • 大保和之, 南澤恵佑, 尾野道男, 中島久仁子, FELLOWS Rachel, 富澤信一. 精子幹細胞分化を制御するエピジェネティックな機構の解析. 日本解剖学会総会・全国学術集会抄録集. 2024. 129th
  • 尾野道男, DOCKAL Ivana, RADOVIC Uros, 大保和之, 富澤信一. Cryptorchidism induces abnormal epigenetic and transcriptional signatures in spermatogonia. 日本解剖学会総会・全国学術集会抄録集. 2023. 128th
  • 富澤信一, FELLOWS Rachel, 尾野道男, 黒羽一誠, DOCKAL Ivana, 南澤恵佑, 鈴木穣, 才津浩智, 大保和之. Role of a novel protease inhibitor for spermatogenesis and immune homeostasis. 日本解剖学会総会・全国学術集会抄録集. 2023. 128th
  • 林亜葵, 中島久仁子, 尾野道男, 富澤信一, 大保和之. WFDCファミリーに属するプロテアーゼインヒビターWFDC2の発現及び機能解析. 日本解剖学会総会・全国学術集会抄録集. 2022. 127th
  • 富澤信一, 小林裕貴, FELLOWS Rachel, 尾野道男, 黒羽一誠, 田中宏光, 河越龍方, 才津浩智, 鈴木穣, 水木信久, et al. Regulation of male germ cell development through KMT2B-dependent epigenetic programming. 日本解剖学会総会・全国学術集会抄録集. 2022. 127th
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Professional career (1):
  • PhD
Work history (4):
  • 2019/04 - 現在 Yokohama City University Histology and Cell Biology, School of Medicine Lecturer/Assistant Professor
  • 2013/03 - 2019/03 Yokohama City University Histology and Cell Biology, School of Medicine Assistant Professor
  • 2009/04 - 2013/02 The Babraham Institute Epigenetics Programme
  • 2006/04 - 2009/03 National Institute of Genetics Division of Human Genetics
Awards (4):
  • 2024/05 - Yokohama City University School of Medicine Hall of Fame, Best Teacher Award
  • 2023/05 - Yokohama City University School of Medicine Best Teacher Award 2022
  • 2022/05 - Yokohama City University School of Medicine Best Teacher Award 2021
  • 2021/05 - Yokohama City University School of Medicine Best Teacher Award 2020
Association Membership(s) (5):
Japan Society of Histochemistry and Cytochemistry ,  THE GENETICS SOCIETY OF JAPAN ,  The Japanese Society for Epigenetics ,  THE JAPANESE ASSOCIATION OF ANATOMISTS ,  THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
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