Rchr
J-GLOBAL ID:201301046448732445
Update date: Oct. 26, 2024
HISATAKE MATSUMOTO
マツモト ヒサタケ | HISATAKE MATSUMOTO
Affiliation and department:
Research field (4):
Molecular biology
, Genetics
, Immunology
, Emergency medicine
Research keywords (1):
Clinical Bioinformatics
Research theme for competitive and other funds (22):
- 2023 - 2028 敗血症性脳症の分子病態統合解析と新規生体指標による積極的治療介入方法の提案
- 2024 - 2027 慢性期外傷性脳損傷はなぜ起きるのか -爆傷による軽症頭部外傷の病態を明らかにする-
- 2024 - 2027 敗血症におけるエピジェネティクス制御因子のメカニズム解明
- 2024 - 2026 侵襲時再生治療に関する新規制御因子の解明:ゲノム・エピゲノム統合解析
- 2023 - 2026 侵襲時再生治療に関する新規制御因子の解明:ゲノム・エピゲノム統合解析
- 2023 - 2026 免疫応答バランスからみた熱傷後の免疫不全メカニズムに関する統合的解析
- 2022 - 2025 網羅的生体分子情報に基づく重症熱傷病態の中心的分子解明と新規治療薬開発
- 2022 - 2025 Immunomolecular pathogenesis of systemic and local lung immunity in ARDS based on integrated analysis
- 2022 - 2025 脂肪細胞による全身性炎症反応制御:オートファジーとアディポカイン産生
- 2022 - 2025 網羅的分子生体情報を用いた頭部外傷患者に対する新たな治療戦略の構築
- 2021 - 2024 シングル細胞シークエンスを用いた敗血症における免疫抑制病態の解明と新規治療法開発
- 2021 - 2024 トランスクリプトームを用いた心停止の分子ネットワーク病態の解明と神経予後予測
- 2020 - 2023 Development of biomarker and molecular pathological classification for optimizing inflammation in sepsis:clinical application of HIVEP1
- 2020 - 2023 Profiling of circulating micro RNA expression in patients with sepsis
- 2019 - 2022 New developments in regenerative therapy for critical illness: the role of novel inflammatory amplification mechanisms.
- 2020 - 2021 新型コロナウイルス感染症(COVID-19)患者の網羅的遺伝子・タンパク発現解析を用いた新規分子病態バイオマーカー開発と臨床応用
- 2020 - トランスクプリトーム解析に基づいた集中治療室における重症患者の新規分子ネットワーク病態解明
- 2016 - 2018 Therapeutic effectiveness of human bone marrow mesenchymal stem cell transplantation in a rat model of crush Injury
- 2015 - 2018 Establishment of methods for immune response analysis of lymphocytes and neutrophils against sepsis and trauma
- 2015 - 2018 Blast induced Traumatic Brain Injury and Cardiovascular Response
- 2014 - 2016 A new therapeutic strategy by suppression of F-actin/DNGR-1 signal in a rat model of crush injury
- 2015 - 転写調整因子HIVEP1を標的と した敗血症におけるNFκBシグナルのメカニズム解明
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Papers (76):
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Shuhei Sakakibara, Yu-Chen Liu, Masakazu Ishikawa, Ryuya Edahiro, Yuya Shirai, Soichiro Haruna, Marwa Ali El Hussien, Zichang Xu, Songling Li, Yuta Yamaguchi, et al. Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients. Life science alliance. 2024. 7. 12
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Kazuhiro Yoneda, Sanae Hosomi, Hiroshi Ito, Yuki Togami, Sayaka Oda, Hisatake Matsumoto, Junya Shimazaki, Hiroshi Ogura, Jun Oda. How can heatstroke damage the brain? A mini review. Frontiers in Neuroscience. 2024. 18
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Arisa Muratsu, Sayaka Oda, Shinya Onishi, Jumpei Yoshimura, Hisatake Matsumoto, Yuki Togami, Yumi Mitsuyama, Hiroshi Ito, Daisuke Okuzaki, Hiroshi Ogura, et al. Bacterial sepsis causes more dramatic pathogenetic changes in the Th1 pathway than does viral (COVID-19) sepsis: a prospective observational study of whole blood transcriptomes. Virology journal. 2024. 21. 1. 190-190
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David G Priest, Takeshi Ebihara, Janyerkye Tulyeu, Jonas N Søndergaard, Shuhei Sakakibara, Fuminori Sugihara, Shunichiro Nakao, Yuki Togami, Jumpei Yoshimura, Hiroshi Ito, et al. Atypical and non-classical CD45RBlo memory B cells are the majority of circulating SARS-CoV-2 specific B cells following mRNA vaccination or COVID-19. Nature communications. 2024. 15. 1. 6811-6811
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Tomonori Okita, Shunbun Kita, Shiro Fukuda, Yuta Kondo, Taka-Aki Sakaue, Masahito Iioka, Keita Fukuoka, Keitaro Kawada, Hirofumi Nagao, Yoshinari Obata, et al. Soluble T-cadherin secretion from endothelial cells is regulated via insulin/PI3K/Akt signalling. Biochemical and biophysical research communications. 2024. 732. 150403-150403
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MISC (115):
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From bedside to bench: Advanced reverse translational research in sepsis in the era of precision medicine. 2024
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松本寿健, 瀬尾茂人, 奥崎大介. 臨床の疑問を分子の言葉に“みえる化”!臨床バイオインフォマティクス 9ステップ 第2回. 実験医学. 2024. 42. 16
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松本寿健, 瀬尾茂人, 奥崎大介. 臨床の疑問を分子の言葉に“みえる化”!臨床バイオインフォマティクス 9ステップ 第1回. 実験医学. 2024. 42. 14
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蛯原健, 松本寿健, 戸上由貴, 戸上由貴, 松浦裕司, 小倉裕司, 織田順. COVID-19と細菌性敗血症における補体活性化の比較. 日本集中治療医学会学術集会(Web). 2024. 51st
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舘野丈太郎, 松本寿健, 瀬尾茂人, 北村哲久, 片山祐介, 小倉裕司, 織田順. 外傷におけるフェノタイプ分類の開発と応用. 日本集中治療医学会学術集会(Web). 2024. 51st
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Patents (5):
Professional career (1):
- MD-PhD (Osaka University)
Awards (3):
- 2022 - Roche INFECTIOUS DISEASE AWARD 2022 Significance of interferon signaling based on mRNA-microRNA integration and plasma protein analyses in critically ill COVID-19 patients.
- 2021 - Roche INFECTIOUS DISEASE AWARD 2022 Combination of WFDC2, CHI3L1, and KRT19 in Plasma Defines a Clinically Useful Molecular Phenotype Associated with Prognosis in Critically Ill COVID-19 Patients
- 2017/09 - European Shock Society Young investor award Unraveling the role of HIVEP1 in innate immunity and sepsis
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