Kondo Naoyuki

コンドウナオユキ | Kondo Naoyuki

Affiliation and department：
Job title： Assistant Professor

Research field (6)： Cell biology , Biophysics , Immunology , Molecular biochemistry , Virology , Functional biochemistry

Research theme for competitive and other funds (16)：

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Papers (46)：

Quynh Thuy Huong Tran, Naoyuki Kondo, Hiroko Ueda, Yoshiyuki Matsuo, Hiroyasu Tsukaguchi. Altered Endoplasmic Reticulum Integrity and Organelle Interactions in Living Cells Expressing INF2 Variants. International Journal of Molecular Sciences. 2024. 25. 18. 9783-9783
Naoyuki Kondo, Yoshihiro Ueda, Tatsuo Kinashi. Low-affinity LFA1-dependent outside-in signaling mediates avidity modulation via the Rabin8-Rab8 axis. PNAS Nexus. 2024
Quynh Thuy Huong Tran, Naoyuki Kondo, Hiroko Ueda, Yoshiyuki Matsuo, Hiroyasu Tsukaguchi. Endoplasmic Reticulum Alterations in Living Cells Expressing INF2 Variants Causing Glomerulosclerosis and Peripheral Neuropathy. 2024
近藤直幸, 大隈和, 塚口裕康, 吉田崇, 上野孝治, 片野泰代. 小胞輸送の超解像イメージングを基軸とした疾患発症・ウイルス感染機構の解明と臨床応用への試み. 関西医科大学雑誌. 2023. 74. 32-33
Sanshiro Kobayashi, Naoyuki Kondo, Takashi Tomiyama, Naohiro Nakamura, Masataka Masuda, Yasushi Matsumoto, Yusuke Honzawa, Tomomitsu Tahara, Tsukasa Ikeura, Toshiro Fukui, et al. Intravenous injection of tumor extracellular vesicles suppresses tumor growth by reducing the regulatory T cell phenotype. Cancer Immunology, Immunotherapy. 2023

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MISC (49)：

近藤直幸. Kindlin-3はインテグリンLFA-1のサブユニット間の会合を阻害してRap1およびtalin1による正のフィードバックを活性化させる. シグナリングに載った日本人研究者2021. 2022. 2022. 10-11
近藤直幸, 植田祥啓, 木梨達雄. 細胞内アダプタータンパク質の一分子動態計測によるインテグリンLFA-1活性化機構の解明. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [1T13e-682)]
近藤直幸, 片野泰代, 赤間智也, 寿野良二, 池田幸樹, 鈴木健介, 富山尚, 神田晃, 八木正夫, 岩井大. 「構造解析コンソーシアム」の確立による分子に基づいた橋渡し研究の推進. 関西医科大学雑誌(Web). 2021. 72
UEDA Yoshihiro, HIGASA Koichiro, KAMIOKA Yuji, KONDO Naoyuki, KINASHI Tatsuo. Rap1 facilitates T cell polarity via spatial regulation of MLC and ARAP1. 日本免疫学会総会・学術集会記録(CD-ROM). 2021. 50
KONDO Naoyuki, UEDA Yoshihiro, KINASHI Tatsuo. Kindlin-3 breaks of integrin LFA-1 inhibitory clasp to promote positive feedback activation of LFA-1 by talin1 and Rap1. 日本免疫学会総会・学術集会記録(CD-ROM). 2021. 50

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Books (2)：

Trends in research for spatio-temporal regulatory mechanism of HIV-Env-mediated membrane fusion & development of a reporter for analysis of the membrane fusion dynamics
Japanese society of biochemistry 2016
Crystallization of insoluble viral protein using new tag protein derived from Thermus thermophilus
2008

Lectures and oral presentations (14)：

Distinct binding properties of integrin adaptors talin1 and kindlin-3 to LFA1 and α4 integrins modulated adhesive responses in static and shear-flow conditions
(2022)
Thermus proteins as versatile tools for detailed analysis functionally unknown protein and efficient protein production
(International workshop on "50th anniversary of Thermus thermophilus discovery" 2018)
NDR1 acts as a molecular hub for the organization of immunological synapse
(第46回日本免疫学会年会 2017)
High affinity LFA-1/ICAM-1 binding triggers the reorganization of vesicular transport regulators to facilitate the maturation of immunological synapse
(第39回日本分子生物学会 2016)
Regulation of high-affinity LFA-1/ICAM-1 binding and immunological synapse formation
(The 36th annual meeting of Japanese immunology society 2015)

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Awards (2)：

Association Membership(s) (3)：

JAPANESE SOCIETY FOR IMMUNOLOGY , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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