Rchr
J-GLOBAL ID:201301060027133626
Update date: Jul. 29, 2024
Konishi Hiroaki
コニシ ヒロアキ | Konishi Hiroaki
Affiliation and department:
Homepage URL (1):
http://kaken.nii.ac.jp/d/r/40252811.ja.html
Research field (2):
Structural biochemistry
, Functional biochemistry
Research keywords (6):
蛋白質リン酸化酵素
, プロテオミクス
, チロシンリン酸化
, 細胞情報伝達機構
, EGF受容体
, シグナル伝達
Research theme for competitive and other funds (20):
- 2020 - 2023 リン酸化プロテオミクスにより新たに見出したアダプタータンパク質の役割の解明
- 2017 - 2021 Elucidation of the physiological functions of the EGF receptor downstream adaptor proteins GAREM and CLPABP
- 2014 - 2017 Functional analysis of the novel adaptor protein, GAREM
- 2007 - 2009 Proteomic analysis of EGF receptor-mediated signaling
- 2007 - 2008 イレッサ感受性診断プロテインチップの創製
- 2007 - 2008 Proteomic identification of the new functional proteins in the EGF receptor-mediated signaling pathway
- 2005 - 2006 ペルオキソーム型Lonプロテアーゼのペルオキシソーム生合成における役割
- 2003 - 2005 Analysis of signaling network by protein-interaction proteomics
- 2003 - 2004 Proteomic and informatic analyses of signal transducing network
- 1999 - 2000 Analysis of function of protein kinase C isozymes in pigment cells by gene transfection using adenovirus vectors
- 1999 - 1999 PHドメインを持つプロテインキナーゼPKBとHsp27との相互作用に関する研究
- 1998 - 1999 Tyrosine phosphorylation and activation of PKC and its role in celluar regulation
- 1998 - 1998 PHドメイン結合物質によるPKB蛋白質リン酸化酵素の活性制御に関する研究
- 1997 - 1998 ストレスによるRACプロテインキナーゼのPH領域を介した活性化機構に関する研究
- 1996 - 1996 RACプロテインキナーゼのPH領域を介した活性化機構に関する解析
- 1996 - 1996 シグナル伝達におけるPHドメインと蛋白質リン酸化酵素活性制御領域の相互作用の解析
- 1995 - 1996 Regulation of the activity of protein kinases depending on their functional domains
- 1995 - 1995 RACプロテインキナーゼ PH領域とプロテインキナーゼCの相互作用に関する解析
- 1995 - 1995 シグナル伝達におけるPHドメインと蛋白質リン酸化酵素活性制御領域の相互作用の解析
- 1994 - 1995 Studies on a protein-serine/threonine protein kinase family having a SH2 domain
Show all
Papers (62):
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Tasuku Nishino, Takaya Abe, Mari Kaneko, Masanao Yokohira, Keiko Yamakawa, Katsumi Imaida, Hiroaki Konishi. GAREM1 is involved in controlling body mass in mice and humans. Biochemical and biophysical research communications. 2022. 628. 91-97
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Tasuku Nishino, Tsuyoshi Oshika, Moriatsu Kyan, Hiroaki Konishi. Effect of the glycine-rich domain in GAREM2 on its unique subcellular localization upon EGF stimulation. Cellular & molecular biology letters. 2021. 26. 1. 16-16
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Tasuku Nishino, Kota Tamada, Akane Maeda, Takaya Abe, Hiroshi Kiyonari, Yasuhiro Funahashi, Kozo Kaibuchi, Toru Takumi, Hiroaki Konishi. Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain. Molecular brain. 2019. 12. 1. 94-94
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Akane Maeda, Tasuku Nishino, Ryota Matsunaga, Atsushi Yokoyama, Hiroshi Suga, Toshiki Yagi, Hiroaki Konishi. Transglutaminase-mediated cross-linking of WDR54 regulates EGF receptor-signaling. Biochimica et biophysica acta. Molecular cell research. 2019. 1866. 2. 285-295
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Hye Ok Kim, Ji Eun Lim, Myung Jun Kim, Ji One Kang, Sung Moon Kim, Jeong Min Nam, Jihoon Tak, Hiroaki Konishi, Tasuku Nishino, In Song Koh, et al. GAREM1 regulates the PR interval on electrocardiograms. Journal of Human Genetics. 2018. 63. 3. 297-307
more...
MISC (3):
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Kyoko Tashiro, Hiroaki Konishi, Hiromi Nabeshi, Emiko Yamauchi, Hisaaki Taniguchi. New functional proteins identified by proteomic analysis in the epidermal growth factor receptor-mediated signaling pathway and application for practical use. Yakugaku Zasshi. 2010. 130. 4. 471-477
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山内英美子, 石野洋子, 小西博昭. プロテオミクスによるタンパク質リン酸化の解析. 生体の科学. 2009. 60. 2
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小西 博昭. EGF受容体下流のプロテオミクスより同定された新規タンパク質の機能解析. 生化学. 2007. 79. 8. 781-785
Education (3):
- 1992 - 1993 The Graduate University for Advanced Studies
- 1988 - 1990 Nagoya University School of Agricultural Sciences
- 1984 - 1988 Nagoya University School of Agricultural Sciences
Work history (6):
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