Rchr
J-GLOBAL ID:201301060027133626   Update date: Jul. 29, 2024

Konishi Hiroaki

コニシ ヒロアキ | Konishi Hiroaki
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/40252811.ja.html
Research field  (2): Structural biochemistry ,  Functional biochemistry
Research keywords  (6): 蛋白質リン酸化酵素 ,  プロテオミクス ,  チロシンリン酸化 ,  細胞情報伝達機構 ,  EGF受容体 ,  シグナル伝達
Research theme for competitive and other funds  (20):
  • 2020 - 2023 リン酸化プロテオミクスにより新たに見出したアダプタータンパク質の役割の解明
  • 2017 - 2021 Elucidation of the physiological functions of the EGF receptor downstream adaptor proteins GAREM and CLPABP
  • 2014 - 2017 Functional analysis of the novel adaptor protein, GAREM
  • 2007 - 2009 Proteomic analysis of EGF receptor-mediated signaling
  • 2007 - 2008 イレッサ感受性診断プロテインチップの創製
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Papers (62):
  • Tasuku Nishino, Takaya Abe, Mari Kaneko, Masanao Yokohira, Keiko Yamakawa, Katsumi Imaida, Hiroaki Konishi. GAREM1 is involved in controlling body mass in mice and humans. Biochemical and biophysical research communications. 2022. 628. 91-97
  • Tasuku Nishino, Tsuyoshi Oshika, Moriatsu Kyan, Hiroaki Konishi. Effect of the glycine-rich domain in GAREM2 on its unique subcellular localization upon EGF stimulation. Cellular & molecular biology letters. 2021. 26. 1. 16-16
  • Tasuku Nishino, Kota Tamada, Akane Maeda, Takaya Abe, Hiroshi Kiyonari, Yasuhiro Funahashi, Kozo Kaibuchi, Toru Takumi, Hiroaki Konishi. Behavioral analysis in mice deficient for GAREM2 (Grb2-associated regulator of Erk/MAPK subtype2) that is a subtype of highly expressing in the brain. Molecular brain. 2019. 12. 1. 94-94
  • Akane Maeda, Tasuku Nishino, Ryota Matsunaga, Atsushi Yokoyama, Hiroshi Suga, Toshiki Yagi, Hiroaki Konishi. Transglutaminase-mediated cross-linking of WDR54 regulates EGF receptor-signaling. Biochimica et biophysica acta. Molecular cell research. 2019. 1866. 2. 285-295
  • Hye Ok Kim, Ji Eun Lim, Myung Jun Kim, Ji One Kang, Sung Moon Kim, Jeong Min Nam, Jihoon Tak, Hiroaki Konishi, Tasuku Nishino, In Song Koh, et al. GAREM1 regulates the PR interval on electrocardiograms. Journal of Human Genetics. 2018. 63. 3. 297-307
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MISC (3):
  • Kyoko Tashiro, Hiroaki Konishi, Hiromi Nabeshi, Emiko Yamauchi, Hisaaki Taniguchi. New functional proteins identified by proteomic analysis in the epidermal growth factor receptor-mediated signaling pathway and application for practical use. Yakugaku Zasshi. 2010. 130. 4. 471-477
  • 山内英美子, 石野洋子, 小西博昭. プロテオミクスによるタンパク質リン酸化の解析. 生体の科学. 2009. 60. 2
  • 小西 博昭. EGF受容体下流のプロテオミクスより同定された新規タンパク質の機能解析. 生化学. 2007. 79. 8. 781-785
Education (3):
  • 1992 - 1993 The Graduate University for Advanced Studies
  • 1988 - 1990 Nagoya University School of Agricultural Sciences
  • 1984 - 1988 Nagoya University School of Agricultural Sciences
Work history (6):
  • 2020/04 - 現在 Shinshu University Faculty of Agriculture
  • 2007/09 - 2020/03 Prefectural University of Hiroshima Faculty of Life and Environmental Scienses
  • 2004/04 - 2004/07 理化学研究所 メンブレンダイナミクス研究グループ 連携研究員
  • 2002/06 - 2004/03 The University of Tokyo Graduate School of Agricultural and Life Sciences
  • 1993/04 - 2002/05 Kobe University
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