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J-GLOBAL ID：201301064729706662 Update date: Mar. 22, 2025

Oyama Akihiko

オヤマアキヒコ | Oyama Akihiko

Affiliation and department：
Job title： Professor and Chairman
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/70374486.ja.html

Research field (2)： Plastic and reconstructive surgery , Surgical dentistry

Research keywords (30)：悪性黒色腫 , 転移 , 骨再生医療 , 唇顎口蓋裂 , バイオセラミックス , ゼラチンハイドロゲル , ケロイド , 神経端側縫合 , 神経二重支配 , cAMP , 線維芽細胞 , 創傷治癒学 , 顔面神経麻痺 , 共培養 , ケロイド線維芽細胞 , 遺伝子治療 , Prostaglandin E2 (PGE2) , リアルタイムPCR , ヒアルロン酸 , 皮膚癌 , PKA , 免疫細胞 , リンパ節 , Myogenin , 癌転移 , 悪性黒色種 , LPA , イメージング , myofibroblast , PAX9

Research theme for competitive and other funds (33)：

2022 - 2027 Mechanism of growth inhibition by cesium on keloid-derived fibroblast
2019 - 2022 Potential abilities of visceral fat:circulation and immunity (hyper 2-way player)
2016 - 2019 Development of functional lymph node transfer
2015 - 2018 The surgical lymphatic regeneration for improving the prognosis of melanoma
2014 - 2017 Elucidation of the pathology of lymphedema and search for effective lymphangiogenesis

2014 - 2017 Investigation of the anti inflammatory and antifibrotic function of regulatory T cells to establish the immune cell therapy in keloid

2014 - 2016 Neurotization through the venous network in muscle : intravenous migration of Schwann cells.

2013 - 2016 Elucidating the collapse of immune system against malignant melanoma

2013 - 2015 The efficiency of side-to-side neurorrhaphy : the condition of donor nerve effects neural recovery.

2013 - 2015 Effect of immunosuppressive agents on the interaction between keloid fibroblasts and CD4+ T cells in a coculture model

2012 - 2015 Imaging of lymph flow in mouse model using in vivo imaging system

2012 - 2014 Effects of estrogen and selective estrogen receptor modulators on normal and keloid fibroblasts

2012 - 2014 Active axonal guidance for reconstruction of facial palsy

2012 - 2014 Mechanism of the improvement of lymphedema with the lymph node transfer

2011 - 2014 Lymph node targeting by human interferon-ß with hyaluronic acid based on metal coordination

2011 - 2013 Controlled release of granulocyte colony-stimulating factor (G-CSF) enhances osteoconductive and biodegradable properties of beta-tricalcium phosphate (beta-TCP) in a rat calvarial defect model

2011 - 2013 Less invasive surgical intervention for cleft lip and palate facilitated normal speech without interfering significantly with maxillofacial growth

2011 - 2013 A New Perspective Of Therapies For Keloids: Application Of An Antifibrotic Medicine

2011 - 2012 Does HGF act as a inhibitor of TGF-β mediated keloid formation?

2010 - 2012 The role of circulating fibrocytes in keloid diathesis.

2010 - 2012 Dynamic change of Myogenin in denervated rat mimetic muscle: Does the neural repair repress its expression ?

2010 - 2012 Clarifying the metastatic mechanisms of melanoma by imaging techniques

2008 - 2010 The influence of interactions between normal lymphatic endothelial cells and melanoma cells on cell migration

2008 - 2010 Can we detect the invasive keloid fibroblasts for the effective treatment?

2007 - 2009 New lymphatic imaging with indocyanine green (ICG) dye labeled hyaluronic acid derivative

2007 - 2008 カーボンナノホーンをキャリアとする創傷に対するドラッグデリバリーシステムの開発

2007 - 2008 Verification of Neural-supercharge technique for incomplete facialpalsy

2006 - 2008 Development of novel therapy for malignant melanoma by morphogenetic gene transfer

2006 - 2006 各種神経疾患に対する支配神経信号の増幅を目指したネットワーク型神経再建法の開発

2005 - 2006 新しいケロイド治療薬としてのcAMP製剤の可能性

2004 - 2005 Novel Strategy for Treatment of Keloid ; Application of siRNA and Keratinocyte

2004 - 2005 Novel gene therapy of keloid by using siRNA

2004 - 2004 毛髪再生医療戦略-HOX遺伝子からのアプローチ-

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Papers (142)：

荻野早紀, 川鍋仁, 福井和徳, 小山明彦. 片側性口唇口蓋裂患児に二次顎裂部骨移植術前後における外鼻形態の比較検討した2症例. 東北矯正歯科学会雑誌. 2024. 32. 1. 3-8
根本奈央子, 川鍋仁, 小山明彦, 岡本亨, 福井和徳. 唇顎口蓋裂児の手術法の違いによる睡眠呼吸動態について. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83回. 234-234
荻野早紀, 川鍋仁, 福井和徳, 小山明彦. Nasoalveolar Molding装置(NAM)を用いた術前顎矯正治療が硬軟組織形態に与える影響. 日本矯正歯科学会大会プログラム・抄録集. 2024. 83回. 235-235
荻野早紀, 川鍋仁, 福井和徳, 小山明彦. 骨格性下顎前突を伴う口唇口蓋裂患者の外科的矯正治療前後における軟組織形態の比較を行った症例. 日本顎変形症学会雑誌. 2024. 34. 2. 169-169
根本奈央子, 川鍋仁, 福井和徳, 小山明彦. コルチコトミー併用による多分割Le Fort I型骨切り術を施術した1症例. 日本顎変形症学会雑誌. 2024. 34. 2. 183-183

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MISC (68)：

川鍋仁, 岡志央理, 村杉嶺, 双石博之, 黒田栄子, 福井和徳, 曽根良子, 加藤美野里, 小山明彦. Three cases of unilateral cleft lip and palate patients treated with all in one surgery. 日本口蓋裂学会雑誌. 2020. 45. 2. 169-169
古川洋志, 大澤昌之, 小山明彦, 村尾尚規, 林利彦, 舟山恵美, 山本有平. 【顔面神経麻痺の治療アルゴリズム:ベストプラクティス】当教室の顔面神経麻痺に対する外科治療のアルゴリズム. 日本頭蓋顎顔面外科学会誌. 2018. 34. 1. 16-20
藤田宗純, 小山明彦, 大澤昌之, 村尾尚規, 林利彦, 舟山恵美, 山本有平. Horse-related Facial Injuries at Our Institution: Report of 4 Cases. 日本頭蓋顎顔面外科学会誌. 2017. 33. 3. 87-92
小山明彦, 岡本亨, 舟山恵美, 佐藤嘉晃, 西澤典子, 今井智子, 山本有平. 片側唇顎口蓋裂に対する一期手術全51症例の経過(その1). 日本口蓋裂学会雑誌. 2017. 42. 2. 93-93
小山明彦, 岡本亨, 舟山恵美, 佐藤嘉晃, 西澤典子, 今井智子, 山本有平. 片側唇顎口蓋裂に対する一期手術全51症例の経過(その2). 日本口蓋裂学会雑誌. 2017. 42. 2. 94-94

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Professional career (1)：

医学博士 (北海道大学)

Work history (2)：

2017/12 - 現在 Fukushima Medical Universituy Department of Plastic and Reconstructive Surgery Professor and Chairman
2009 - 2017/11 Hokkaido University Department of Plastic and Reconstructive Surgery

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