Research theme for competitive and other funds (16):
2024 - 2027 Assessing the risk of lung cancer development and malignant transformation caused by PM2.5, as well as elucidating its mechanism of action
2024 - 2026 インフルエンザ感染におけるM細胞の誘導機構と感染病態における役割の解明
2023 - 2026 インフルエンザ感染におけるM細胞の誘導機構と感染病態における役割の解明
2019 - 2022 Elucidation of differentiation and function of M cell in the airway
2019 - 2022 呼吸器M細胞による外因性微粒子取り込み機構とその生物学的意義の解明
2016 - 2019 Effects of cellular mechanical environment on response to interleukin-1beta stimulation in isolated tenocytes
2016 - 2019 Molecular mechanisms underlying differentiation of intestinal M cells
2015 - 2019 Roles of a novel key regulatory molecule, USP2, in energy homeostasis
2016 - 2018 腸管特殊上皮M細胞成熟過程における転写制御機構の解析
2013 - 2016 Host-microbe interaction mediated by intestinal M cells
2013 - 2016 Visualization of the entire differentiation process of murine M cells: suppression of their maturation in cecal patches.
2012 - 2015 Modulatory effects of macrophage M-mod/USP2 on type2 diabetes
2012 - 2015 The possibility of M-cell differentiation regulated by novel intercellular communication system
2011 - 2012 Study on the interaction between M cells and immune cells in Peyer' spatch.
2008 - 2012 Regulation of mucosal immune system by polarized sorting in epithelial cells
2009 - 2010 Visualization and molecular analysis of antigen-uptake and -delivery at M cell.
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Papers (66):
Randa A Abdelnaser, Masateru Hiyoshi, Naofumi Takahashi, Youssef M Eltalkhawy, Hidenobu Mizuno, Shunsuke Kimura, Koji Hase, Hiroshi Ohno, Kazuaki Monde, Akira Ono, et al. Identification of TNFAIP2 as a unique cellular regulator of CSF-1 receptor activation. Life science alliance. 2025. 8. 5
Yuki Oya, Shunsuke Kimura, Maho Uemura, Yumiko Fujimura, Koji Hase. Tear duct M cells exacerbate allergic conjunctivitis by facilitating germinal-center reactions. Mucosal Immunology. 2025
Federica Barutta, Beatrice Corbetta, Stefania Bellini, Roberto Gambino, Stefania Bruno, Shunsuke Kimura, Koji Hase, Hiroshi Ohno, Gabriella Gruden. Protective effect of mesenchymal stromal cells in diabetic nephropathy: the In vitro and In vivo role of the M-Sec-tunneling nanotubes. Clinical science (London, England : 1979). 2024. 138. 23. 1537-1559
Ryohtaroh Matsumoto, Kosuke Ogata, Daisuke Takahashi, Yusuke Kinashi, Takahiro Yamada, Ryo Morita, Keisuke Tanaka, Kouya Hattori, Mayumi Endo, Yumiko Fujimura, et al. AP-1B regulates interactions of epithelial cells and intraepithelial lymphocytes in the intestine. Cellular and Molecular Life Sciences. 2024. 81. 1. 425-425
Yusuke Kinashi, Keisuke Tanaka, Shunsuke Kimura, Masato Hirota, Seiga Komiyama, Tomoko Shindo, Akinori Hashiguchi, Daisuke Takahashi, Shinsuke Shibata, Shin-Ichiro Karaki, et al. Intestinal epithelium dysfunctions cause IgA deposition in the kidney glomeruli of intestine-specific Ap1m2-deficient mice. EBioMedicine. 2024. 106. 105256-105256
Molecular mechanisms of plasma membrane deformation by M-Sec during TNT formation
(GSK meeting Tunneling Nanotubes (TNTs) - Cell-to-Cell Social Networking in Disease Conference 2016)