Rchr
J-GLOBAL ID:201301074152576786   Update date: Jun. 11, 2024

Aoyama Koji

アオヤマ コウジ | Aoyama Koji
Affiliation and department:
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/00420943.ja.html
Research field  (2): Pharmacology ,  Neuroscience - general
Research keywords  (13): アルツハイマー病 ,  グルタチオン ,  EAAC1 ,  GTRAP3-18 ,  神経変性疾患 ,  MPTP ,  パーキンソン病 ,  EAAT3 ,  遺伝子破壊マウス ,  酸化ストレス抵抗性 ,  神経細胞 ,  システイン ,  遺伝子改変マウス
Research theme for competitive and other funds  (11):
  • 2023 - 2026 Analysis of novel peptide nucleic acids against neurodegeneration
  • 2021 - 2024 マイクロバブル超音波法を用いた核酸薬経鼻投与による神経変性疾患の新規治療戦略
  • 2020 - 2023 プリン体および尿酸の骨髄幹細胞活性に与える影響
  • 2020 - 2023 核酸薬を用いた肥満・高血糖を伴う認知機能低下に対する治療戦略
  • 2016 - 2020 グルタチオン産生促進物質の経鼻投与による神経変性疾患治療法の開発
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Papers (66):
  • Nobuko Matsumura, Koji Aoyama. Glutathione-Mediated Neuroprotective Effect of Purine Derivatives. International journal of molecular sciences. 2023. 24. 17
  • Nobuko Matsumura, Chisato Kinoshita, Wattanaporn Bhadhprasit, Toshio Nakaki, Koji Aoyama. A purine derivative, paraxanthine, promotes cysteine uptake for glutathione synthesis. Journal of pharmacological sciences. 2023. 151. 1. 37-45
  • Chisato Kinoshita, Noriko Kubota, Koji Aoyama. Glutathione Depletion and MicroRNA Dysregulation in Multiple System Atrophy: A Review. International journal of molecular sciences. 2022. 23. 23
  • Chisato Kinoshita, Noriko Kubota, Koji Aoyama. Interplay of RNA-Binding Proteins and microRNAs in Neurodegenerative Diseases. International Journal of Molecular Sciences. 2021
  • Matsumura Nobuko, Kinoshita Chisato, Nakaki Toshio, Aoyama Koji. The development of miR-96-5p gene knock out technique by CRISPR/Cas9 system. Proceedings for Annual Meeting of The Japanese Pharmacological Society. 2021. 94. 0. 3-P1-37
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MISC (35):
Patents (3):
Books (7):
  • Course and duration of therapy with Parkinsonian drugs, and withdrawal syndromes. In: Riederer P, et al., eds. NeuroPsychopharmacotherapy.
    Springer 2019
  • eReview薬理学
    エルゼビア・ジャパン 2019
  • Clinical Neuroscience
    2018
  • Lippincott Illustrated Reviews Pharmacology
    2016
  • 集中講義 薬理学
    株式会社メジカルビュー社 2015
more...
Education (2):
  • - 2002 Shimane Medical University
  • - 1995 Shimane Medical University
Professional career (1):
  • 博士(医学)
Work history (6):
  • 2018/04 - 現在 Teikyo University School of Medicine Professor
  • 2013/01 - Teikyo University School of Medicine Associate Professor
  • 2005/09 - Teikyo University School of Medicine Assistant Professor
  • 2002/03 - 2005/08 University of California at San Francisco VA Medical Center, Department of Neurology Postdoctoral fellow
  • 1996 - 東京都済生会中央病院 内科 研修医
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Committee career (1):
  • 2011 - 現在 日本薬理学会 学術評議委員
Awards (1):
  • 2019/03 - 35th International Symposium on Microscale Separations and Bioanalysis. Oregon State University, USA. Award of Excellence for an outstanding poster presentation. Measurement of neuronal glutathione levels in the brain.
Association Membership(s) (4):
日本生理学会 ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  JAPANESE SOCIETY OF NEUROLOGY ,  THE JAPANESE SOCIETY OF INTERNAL MEDICINE
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