Rchr
J-GLOBAL ID:201301074358722380
Update date: Jul. 20, 2024
MASANORI SASAKI
ササキ マサノリ | MASANORI SASAKI
Affiliation and department:
Homepage URL (1):
http://kaken.nii.ac.jp/d/r/20538136.ja.html
Research field (1):
Neurosurgery
Research theme for competitive and other funds (54):
- 2023 - 2026 Intravenous infusion of exosome for the treatment of neonatal hypoxic ischemic encephalopathy
- 2023 - 2026 Bone marrow mesenchymal stem cell transplantation prevents concurrent progression of chronic kidney disease and associated cerebrovascular disease
- 2024 - 2025 Therapeutic strategies for cerebral infarction and spinal cord injury by activating plasticity throughout the central nervous system
- 2022 - 2025 健康寿命延長に関与する骨髄幹細胞の自己治癒能と全身の恒常性維持
- 2022 - 2025 脊損に対する骨髄幹細胞治療で介在ニューロンの関与で再構築された神経回路の解析
- 2022 - 2025 Development of innovative treatments using next-generation exosomes for cerebral infarction
- 2022 - 2025 脳梗塞と脊髄損傷に対する中枢神経系全域の可塑性賦活化による治療戦略の検討
- 2022 - 2025 Development of novel treatments and elucidation of mechanisms for intractable epilepsy using bone marrow mesenchymal stem cells
- 2021 - 2024 慢性期脳梗塞に対する骨髄幹細胞とリハビリ併用による脳のplasticityの解析
- 2021 - 2024 神経障害性疼痛に対する間葉系幹細胞の治療効果の検討
- 2021 - 2024 Development of innovative treatment for spinal cord injury using next-generation exosomes
- 2021 - 2024 脊髄障害性疼痛に対する骨髄間葉系幹細胞を用いた治療法の開発
- 2021 - 2024 脊髄損傷に対する骨髄間葉系幹細胞移植による、脳脊髄での可塑性亢進メカニズムの解析
- 2021 - 2024 骨髄幹細胞治療における機能活性モニタリングと機能予後バイオマーカーの開発
- 2021 - 2024 Reconstructed neural circuits following intravenous infusion of mesenchymal stem cells in a rat model of experimental cerebral ischemia
- 2021 - 2024 Intravenous infusion of mesenchymal stem cells for chronic spinal cord ischemia
- 2020 - 2023 脳梗塞に対する骨髄幹細胞治療における分子メカニズムに基づく至適リハビリ条件の探索
- 2020 - 2023 神経膠腫の浸潤機序解析と浸潤能を標的とした先駆的治療法の開発
- 2020 - 2023 Mesenchymal stem cells for brain injury of prematurity in a rat model.
- 2020 - 2023 脊髄損傷に対する骨髄幹細胞治療でダイナミックに再構築された神経回路の機能解析
- 2019 - 2022 Extended lifespan induced by mesenchymal stem cells
- 2019 - 2022 Mesenchymal stem cell therapy for experimental stroke
- 2019 - 2022 The development of novel therapies for intractable epilepsy with bone marrow mesenchymal stem cells
- 2018 - 2021 Intravenous infusion of mesenchymal stem cells alleviates interstitial cystitis/bladder pain syndrome in a Toll-like receptor-7 agonist-induced rat model
- 2018 - 2021 Analysis of the neural circuits reconstructed by interneurons in mesenchmal stem cell transplantation for spinal cord injury
- 2018 - 2021 Intravenous infusion of mesenchymal stem cells enhance plasticity in the brain of rat model of experimental spinal cord injury
- 2018 - 2021 Analysis of accelerating plasticity in the brain following intravenous infusion of mesenchymal stem cells in spinal injury
- 2018 - 2021 Intravenous infusion of mesenchymal stem cells for experimental ALS
- 2018 - 2021 Intravenous infusion of mesenchymal stem cells for spinal cord ischemia
- 2018 - 2021 New therapeutic strategy for refractory depression: analysis of neuron remodeling using stem cell treatment
- 2017 - 2020 Functional recovery following intravenous infusion of mesenchymal stem cells via induction of neural plasticity in chronic spinal cord injury
- 2017 - 2020 Improvement in neural function following intravenous infusion of mesenchymal stem cells in experimental cerebral stroke
- 2017 - 2020 analysis of molecular mechanism of invasion in malignant gliomas and development of a novel treatment by inhibition of glioma cell migrations
- 2017 - 2020 筋萎縮性側索硬化症に対する骨髄間葉系幹細胞移植による新たな治療法の開発
- 2017 - 2020 Induced neural plasticity following combination of intravenous infusion of Mesenchymal Stem Cells and Rehabilitation after stroke in rats
- 2016 - 2019 Analysis of neural functional recovery mechanism immediately after bone marrow stem cell transplantation for spinal cord injury
- 2016 - 2019 Intravenous infusion of mesenchymal stem cells reduces erectile dysfunction following cavernous nerve injury in rats
- 2016 - 2019 Functional recovery following intravenous infusion of mesenchymal stem cells in experimental spinal cord injury
- 2016 - 2019 脳海綿状血管腫に対する分子標的療法の開発
- 2016 - 2019 Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells
- 2016 - 2019 Development of new therapy with mesenchymal stem cell for reperfusion injury following reperfusion therapy
- 2016 - 2019 The development of novel therapies for intractable epilepsy with bone marrow mesenchymal stem cells
- 2015 - 2018 Analysis of neural plasticity induced by intravenous infusion of mesenchymal stem cells in experimental model of cerebral infarction
- 2015 - 2018 Restoration of cognitive impairment following intravenous infusion of mesenchymal stem cells in a rat model of cerebral small vessel disease
- 2014 - 2017 Fundamental analysis of ischemic brain plasticity induced by bone marrow mesenchymal stem cell transplantation
- 2014 - 2017 INTRAVENOUS INFUSION OF MESENCHYMAL STEM CELLS PROMOTES FUNCTIONAL RECOVERY IN A MODEL OF CHRONIC SPINAL CORD INJURY
- 2014 - 2017 Target therapy for high grade glioma by using specific antibody against glioma stem cell
- 2014 - 2017 Therapeutic Effects of Intravenous Infusion of MSCs in Hypoxic-Ischemic Encephalopathy Rat
- 2014 - 2017 Induced neural plasticity by intravenous infusion of mesenchymal stem cells (MSC) and rehabilitation in ischemic brain
- 2013 - 2016 骨髄幹細胞移植による海綿体神経の保護・再生と勃起機能の温存
- 2013 - 2016 Functional recovery following intravenous infusion of MSCs via repair of pericytes in rat spinal cord injury
- 2013 - 2016 Profile analysis of mesenchymal stem cell for cellular therapy
- 2012 - 2015 Characteristic analysis of mesenchymal stem cells for regenerative medicine
- 2012 - 2014 脊髄損傷の病態生理におけるペリサイトの動向~骨髄幹細胞移植による機能回復の機序~
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Papers (91):
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Kota Kurihara, Masanori Sasaki, Hiroshi Nagahama, Hisashi Obara, Ryunosuke Fukushi, Ryosuke Hirota, Mitsunori Yoshimoto, Atsushi Teramoto, Jeffery D Kocsis, Toshihiko Yamashita, et al. Repeated intravenous infusion of mesenchymal stem cells enhances recovery of motor function in a rat model with chronic spinal cord injury. Brain research. 2023. 1817. 148484-148484
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Kojiro Terada, Masanori Sasaki, Hiroshi Nagahama, Yuko Kataoka-Sasaki, Shinichi Oka, Ryo Ukai, Takahiro Yokoyama, Yusuke Iizuka, Takuro Sakai, Shinobu Fukumura, et al. Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injury. Pediatric research. 2023
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Hiroshi Nagahama, Masanori Sasaki, Katsuya Komatsu, Kaori Sato, Yoshimi Katagiri, Masaki Kamagata, Yuko Kataoka-Sasaki, Shinichi Oka, Ryo Ukai, Takahiro Yokoyama, et al. A practical protocol for high-spatial-resolution magnetic resonance angiography for cerebral arteries in rats. Journal of neuroscience methods. 2023. 386. 109784-109784
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Shusaku Maeda, Takuji Kawamura, Masanori Sasaki, Kazuo Shimamura, Takashi Shibuya, Akima Harada, Osamu Honmou, Yoshiki Sawa, Shigeru Miyagawa. Intravenous infusion of bone marrow-derived mesenchymal stem cells improves tissue perfusion in a rat hindlimb ischemia model. Scientific reports. 2022. 12. 1. 16986-16986
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Ryosuke Hirota, Masanori Sasaki, Yuko Kataoka-Sasaki, Tsutomu Oshigiri, Kota Kurihara, Ryunosuke Fukushi, Shinichi Oka, Ryo Ukai, Mitsunori Yoshimoto, Jeffery D. Kocsis, et al. Enhanced Network in Corticospinal Tracts after Infused Mesenchymal Stem Cells in Spinal Cord Injury. Journal of Neurotrauma. 2022. 39. 23-24. 1665-1677
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MISC (32):
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安田 尚美, 佐々木 祐典, 佐々木 優子, 長濱 宏, Jeffry D. Kocsis, 川原田 修義, 本望 修. 虚血性脊髄障害モデルに対する間葉系幹細胞静脈投与の治療効果の検討-Intravenous delivery of mesenchymal stem cells protects both white and gray matter in spinal cord ischemia. 北海道外科雑誌 = The Hokkaido journal of surgery / 北海道外科雑誌編集委員会 編. 2021. 66. 1. 50-52
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本田 修, 中崎 公仁, 佐々木 祐典, 野中 雅, 高橋 明, 橋本 祐治, 米増 保之, 野村 達史, 恩田 敏之, 大坊 雅彦. T1 Black Blood imagingによる椎骨動脈解離の経時的変化(Temporal Change of Signal Intensity of Intramural Hematoma in Patients with Acute Vertebral Artery Dissection Using T1-Weighted Black Blood Imaging). CI研究. 2017. 39. 2. 71-77
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中崎 公仁, 野中 雅, 野村 達史, 恩田 敏之, 米増 保之, 高橋 明, 橋本 祐治, 本田 修, 佐々木 祐典, 大坊 雅彦, et al. 脳小血管病と急性再開通治療3ヵ月後の臨床転帰との関係. 脳血管内治療. 2017. 2. Suppl. S170-S170
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中崎公仁, 野中雅, 野村達史, 恩田敏之, 野中雅, 野村達史, 恩田敏之, 米増保之, 高橋明, 橋本祐治, et al. 脳小血管病と緊急血栓回収療法の臨床転帰との関係. 脳循環代謝(Web). 2017. 29. 1. 159-159
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佐々木雄一, 佐々木雄一, 佐々木雄一, 佐々木雄一, 佐々木祐典, 佐々木祐典, 佐々木優子, 佐々木優子, 中崎公仁, 中崎公仁, et al. Therapeutic effect by combining rehabilitation and intravenous infusion of mesenchymal stem cells after experimental stroke in rats. 脳循環代謝(Web). 2017. 28. 2. 281-289(J-STAGE)-289
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Work history (3):
- 2020/04 - 現在 Sapporo Medical University Research Institute for Frontier Medicine
- 2012/08 - 2020/03 Sapporo Medical University Research Institute for Frontier Medicine
- 2012/01 - 2012/07 Sapporo Medical University Research Institute for Frontier Medicine
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