TAKAHITO SANADA

サナダタカヒト | TAKAHITO SANADA

Affiliation and department：
Homepage URL (1)： http://kaken.nii.ac.jp/d/r/00569957.ja.html

Research field (5)： Neuropathology , Laboratory animal science , Cell biology , Morphology, anatomy , Bacteriology

Research keywords (3)： CLEM , In-resin CLEM , 神経変性

Research theme for competitive and other funds (2)：

2016 - 2019 炎症抑制エフェクター欠損株を利用した細菌感染病態の解析
2010 - 2012 新規赤痢菌III型分泌タンパクによるNF-kB活性化の抑制機構の解明

Papers (32)：

Chigure Suzuki, Junji Yamaguchi, Takahito Sanada, Juan Alejandro Oliva Trejo, Souichirou Kakuta, Masahiro Shibata, Isei Tanida, Yasuo Uchiyama. Lack of Cathepsin D in the central nervous system results in microglia and astrocyte activation and the accumulation of proteinopathy-related proteins. Scientific reports. 2022. 12. 1. 11662-11662
Takahito Sanada, Junji Yamaguchi, Yoko Furuta, Soichiro Kakuta, Isei Tanida, Yasuo Uchiyama. In-resin CLEM of Epon-embedded cells using proximity labeling. Scientific reports. 2022. 12. 1. 11130-11130
Ryo Kinoshita-Daitoku, Kotaro Kiga, Masatoshi Miyakoshi, Ryota Otsubo, Yoshitoshi Ogura, Takahito Sanada, Zhu Bo, Tuan Vo Phuoc, Tokuju Okano, Tamako Iida, et al. A bacterial small RNA regulates the adaptation of Helicobacter pylori to the host environment. Nature Communications. 2021. 12. 1
Ryo Kinoshita-Daitoku, Kotaro Kiga, Takahito Sanada, Yoshitoshi Ogura, Zhu Bo, Tamako Iida, Rui Yokomori, Eisuke Kuroda, Mototsugu Tanaka, Arpana Sood, et al. Mutational diversity in mutY deficient Helicobacter pylori and its effect on adaptation to the gastric environment. Biochemical and biophysical research communications. 2020. 525. 3. 806-811
Mototsugu Tanaka, Ryo Kinoshita-Daitoku, Kotaro Kiga, Takahito Sanada, Bo Zhu, Tokuju Okano, Chihiro Aikawa, Tamako Iida, Yoshitoshi Ogura, Tetsuya Hayashi, et al. Group A Streptococcus establishes pharynx infection by degrading the deoxyribonucleic acid of neutrophil extracellular traps. Scientific reports. 2020. 10. 1. 3251-3251

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MISC (12)：

木下遼, 木下遼, 氣駕恒太朗, 大坪亮太, 小椋義俊, 眞田貴人, 眞田貴人, 岡野徳壽, 鈴木敏彦, 山岡吉生, et al. sRNA regulates pathogenicity during persistent infection of Helicobacter. 日本細菌学雑誌(Web). 2020. 75. 1
鈴木志穂, 三室仁美, 小川道永, 芦田浩, 鈴木仁人, 真田貴人, 笹川千尋. 赤痢菌IpaH7.8 E3ユビキチンリガーゼはglomulinを標的化して炎症を活性化する(Shigella IpaH7.8 E3 ubiquitin ligase targets glomulin to activate inflammasomes). 日本細菌学雑誌. 2015. 70. 1. 217-217
真田貴人, 笹川千尋. 赤痢菌による宿主自然免疫の抑制機構. 感染・炎症・免疫. 2013. 43. 2. 168-169
小林泰良, 小川道永, 真田貴人, 三室仁美, 笹川千尋. 腸管感染細菌の病原システム赤痢菌の感染戦略宿主細胞の炎症性細胞死に抗うカスパーゼ阻害エフェクター(A Bacterial Caspase Inhibitor Antagonizes Inflammatory Cell Death and Promotes Epithelial Infection). 日本細菌学雑誌. 2013. 68. 1. 113-113
小林泰良, 小川道永, 真田貴人, 三室仁美, 笹川千尋. 赤痢菌の感染戦略宿主細胞の炎症性細胞死に抗うカスパーゼ阻害エフェクター(A Bacterial Caspase Inhibitor Antagonizes Inflammatory Cell Death and Promotes Epithelial Infection). 日本細菌学雑誌. 2013. 68. 1. 164-164

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Work history (1)：

2020/04 - 現在順天堂大学老人性疾患病態・治療研究センター老人性疾患病態・治療研究センター特任研究員

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