Rchr
J-GLOBAL ID:201401000826945620
Update date: Jan. 06, 2025 Murakami Kazuhiro
ムラカミ カズヒロ | Murakami Kazuhiro
Affiliation and department: Job title:
Associate Professor
Homepage URL (1): http://ganken.cri.kanazawa-u.ac.jp/about/department/epithelial_stem_cell_biology/ Research field (4):
Tumor biology
, Molecular biology
, Cell biology
, Developmental biology
Research keywords (6):
Stem Cell BIology
, Tissue Stem Cells
, Gastrointestinal cancer
, Cancer Stem Cell
, Wnt
, Lgr5
Research theme for competitive and other funds (7): - 2023 - 2026 胃がんオルガノイドを用いた幹細胞制御因子の同定と検証
- 2020 - 2023 Analysis of mechanisms which regulate stemness in stomach tumor and searching of new treatment.
- 2017 - 2020 Visualization of cancer-initiating cells and search for an effective treatment using gastric cancer organoids
- 2017 - 2019 Analysis of gastric cancer stem cells and regulatory mechanism.
- 2015 - 2017 Analysis of the mechanism which regulates germ cell development in cooperation with transcription factors
- 2007 - 2008 Mechanical analysis for carcinogenesis by functional studies of non-coding RNA
- 2004 - 2006 クロマチンの動的変化を伴う遺伝子発現制御機構の解明
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Papers (40): -
Mizuho Nakayama, Hiroshi Saito, Kazuhiro Murakami, Hiroko Oshima, Masanobu Oshima. Missense Mutant p53 Transactivates Wnt/β-Catenin Signaling in Neighboring p53-Destabilized Cells through the COX-2/PGE2 Pathway. Cancer research communications. 2025
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Daichi Sato, Makoto Arimoto, Ayumi Ishiguro, Fitri Lucyana, Takahiro Tomoda, Kenichiro Okumura, Hiroki Kawashima, Satoshi Kobayashi, Kazuhiro Murakami, Jun Kataoka, et al. Multi-energy in-vivo imaging of multiple contrast agents in a mouse using MPPC-based photon-counting CT. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 2024. 1064. 169337-169337
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D. Sato, M. Arimoto, J. Kotoku, H. Kawashima, S. Kobayashi, K. Okumura, K. Murakami, F. Lucyana, T. Tomoda, J. Kataoka, et al. Sparse-view image reconstruction with total-variation minimization applied to sparsely sampled projection data from SiPM-based photon-counting CT. Journal of Instrumentation. 2024. 19. 02. C02010-C02010
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Daichi Sato, Makoto Arimoto, Kotaro Yoshiura, Tomoya Mizuno, Ko Aiga, Kairi Ishiguro, Takahiro Tomoda, Hiroki Kawashima, Satoshi Kobayashi, Kenichiro Okumura, et al. Initial results of in vivo CT imaging of contrast agents using MPPC-based photon-counting CT. Nuclear instruments and methods in physics research, section a: Accelerators, spectrometers, detectors and associated equipment. 2023. 1048
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Atsuya Morita, Mizuho Nakayama, Dong Wang, Kazuhiro Murakami, Masanobu Oshima. Frequent loss of metastatic ability in subclones of Apc , Kras , Tgfbr2 , and Trp53 mutant intestinal tumor organoids. Cancer Science. 2023. 114. 4. 1437-1450
more... MISC (25): -
村上 和弘, Barker Nick. Lgr5陽性の胃がん細胞において幹細胞性を導く機構の解析(Analysis of mechanisms which regulate the tumor malignancy in Lgr5 expressing gastric cancer cells). 日本癌学会総会記事. 2022. 81回. J-2012
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村上 和弘. 胃組織の幹細胞らしさを決める新たな分子機構の発見. バイオサイエンスとインダストリー. 2022. 80. 1. 44-46
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村上和弘, 寺門侑美, BARKER Nick, BARKER Nick. LGR5陽性の胃がん細胞において幹細胞性を導く機構の解析. 日本癌学会学術総会抄録集(Web). 2021. 80th
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寺門侑美, 村上和弘, 大島浩子, 大島正伸, BARKER Nick, BARKER Nick. 進行性胃癌発生および進行における腫瘍内Lgr5陽性幹細胞プールの役割. 日本癌学会学術総会抄録集(Web). 2021. 80th
- 佐藤 拓輝, 今村 龍, 酒井 克也, 大島 浩子, 大島 正伸, 村上 和弘, 寺門 侑美, 加藤 幸成, 矢野 聖二, 松本 邦夫. 胃組織修復および発がん機構における活性型HGFの役割. 日本癌学会総会記事. 2020. 79回. OJ13-3
more... Education (1): - 2004 - 2007 Tottori University Graduate School of Medical Sciences
Professional career (1): Work history (5): - 2022/02 - 現在 Cancer Research Institute, Kanazawa University Division of Epithelial Stem Cell Biology Associate Professor
- 2016/04 - 2022/01 Cancer Research Institute, Kanazawa University Division of Epithelial Stem Cell Biology Assistant Professor
- 2013/09 - 2016/03 Hokkaido University
- 2011/04 - 2013/08 Wellcome Trust/ Cancer Research UK Gurdon Institute Azim Surani laboratory Research associate
- 2007/04 - 2011/03 RIKEN Centre for Developmental Biology Laboratory for Pluripotent Cell Studies Research associate
Association Membership(s) (3):
JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS
, THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, THE JAPANESE CANCER ASSOCIATION
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