Nakaoka Hirofumi

ナカオカヒロフミ | Nakaoka Hirofumi

Affiliation and department：
Job title：部長

Research field (2)： Medical biochemistry , Genomics

Research theme for competitive and other funds (15)：

2024 - 2027 正常組織における変異クローンの空間的増殖を誘導する遺伝・環境要因相互作用の解明
2024 - 2027 Construction of gene expression atlas of normal endometrium and elucidation of regeneration mechanism by spatial omics analysis
2023 - 2027 Gene-environment interactions inducing spatial expansion of mutant clones in human normal tissues
2024 - 2026 稀な血液型における生活習慣病リスクの証明:判定方法の正確性向上と予防医学への挑戦
2022 - 2025 Identification of the significance of cancer-associated gene mutations in normal endometrium

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Papers (119)：

Luca Nishimura, Akio Tanino, Mayumi Ajimoto, Takafumi Katsumura, Motoyuki Ogawa, Kae Koganebuchi, Daisuke Waku, Masahiko Kumagai, Ryota Sugimoto, Hirofumi Nakaoka, et al. Metagenomic analyses of 7000 to 5500 years old coprolites excavated from the Torihama shell-mound site in the Japanese archipelago. PloS one. 2024. 19. 1. e0295924
Hidehiko Akashi, Nozomi Yachida, Haruka Ueda, Manako Yamaguchi, Kaoru Yamawaki, Ryo Tamura, Kazuaki Suda, Tatsuya Ishiguro, Sosuke Adachi, Yoshikazu Nagase, et al. SLFN11 is a BRCA independent biomarker for the response to platinum-based chemotherapy in high-grade serous ovarian cancer and clear cell ovarian carcinoma. Molecular cancer therapeutics. 2023
Ryo Tamura, Hirofumi Nakaoka, Nozomi Yachida, Haruka Ueda, Tatsuya Ishiguro, Teiichi Motoyama, Ituro Inoue, Takayuki Enomoto, Kosuke Yoshihara. Spatial genomic diversity associated with APOBEC mutagenesis in squamous cell carcinoma arising from ovarian teratoma. Cancer science. 2023. 114. 5. 2145-2157
Detecting and Quantifying Donor derived cell free DNA in the blood of kidney transplant recipients as a biomarker for graft injury and immunosuppression. Organ Biology. 2023. 30. 1. 7-14
Yu Toyoda, Masahiro Nakatochi, Akiyoshi Nakayama, Yusuke Kawamura, Hirofumi Nakaoka, Kenji Wakai, Keitaro Matsuo, Hirotaka Matsuo. SNP-based heritability estimates of gout and its subtypes determined by genome-wide association studies of clinically defined gout. Rheumatology (Oxford, England). 2022

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MISC (12)：

Hirotaka Matsuo, Toshihide Higashino, Tappei Takada, Hirofumi Nakaoka, Yu Toyoda, Blanka Stiburkova, Hiroshi Nakashima, Seiko Shimizu, Makoto Kawaguchi, Akiyoshi Nakayama, et al. Comprehensive Association Analysis between Rare and Common ABCG2 Variants and Gout Susceptibility. ARTHRITIS & RHEUMATOLOGY. 2018. 70
Higashino T, Takada T, Nakaoka H, Toyoda Y, Stiburkova B, Wakai K, Ooyama H, Inoue I, Merriman T. R, Shinomiya N, et al. COMPREHENSIVE EVALUATION OF THE EFFECTS OF RARE AND COMMON EXONIC ABCG2 VARIANTS ON GOUT SUSCEPTIBILITY. ANNALS OF THE RHEUMATIC DISEASES. 2018. 77. 230-231
Yuki Matsumoto, Tatsuhiko Goto, Hirofumi Nakaoka, Jo Nishino, Akira Tanave, Richard F. Mott, Tsuyoshi Koide. Wild-derived heterogeneous stock mice to find the loci associated with tame behavior. GENES & GENETIC SYSTEMS. 2014. 89. 6. 314-314
芳賀秀郷, 山口徹太郎, 中岡博史, 佐本博, 井ノ上逸朗, 槇宏太郎. 第三大臼歯欠如をもたらす遺伝因子の探索. 東京矯正歯科学会雑誌. 2013. 23. 2. 119-119
芳賀秀郷, 山口徹太郎, 中岡博史, 佐本博, 大野粛英, 井ノ上逸朗, 槇宏太郎. ゲノムワイド関連解析から同定される第三大臼歯欠如をもたらす遺伝要因の探索. 日本矯正歯科学会大会プログラム・抄録集. 2013. 72回. 286-286

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Education (2)：

Professional career (1)：

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