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J-GLOBAL ID：201401011700904369 Update date: Feb. 01, 2024

Noda Natsumi

ノダナツミ | Noda Natsumi

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Affiliation and department：
Job title：特任研究員

Research field (1)： Tumor biology

Research keywords (10)： Split-luciferase complementation , CD44 , Cancer stem cells , Breast cancer , Optogenetics , Transcriptional regulation , Bioluminescence , Luciferase , Cancer , Bioluminescence imaging

Research theme for competitive and other funds (6)：

2018 - 2023 乳癌幹細胞を標的とした治療法探索のための発光プローブの開発
2015 - 2018 Construction of screening system of food and drug for prevention/diagnosis/treatment of NASH using new biomarker
2015 - 2018 Development of biological diagnosis and treatment of pancreatic cancer using a new intracellular molecule
2015 - 2018 Light-controllable transcription system for pancreatic cancer therapy
2014 - 2016 Basic study of the relevance of programmed cell death in the maintenance and regulation of liver function and regeneration for the future clinical use.

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Papers (8)：

Natsumi Noda, Takeaki Ozawa. Castanospermine suppresses CD44 ectodomain cleavage as revealed by transmembrane bioluminescent sensors. Journal of Cell Science. 2022. 135. 6. jcs259314
Liang Bao, Natsumi Inoue, Masaki Ishikawa, Eiji Gotoh, Ooi-Kock Teh, Takeshi Higa, Tomoro Morimoto, Eggie Febrianto Ginanjar, Hirofumi Harashima, Natsumi Noda, et al. A PSTAIRE-type cyclin-dependent kinase controls light responses in land plants. Science Advances. 2022. 8. 4. eabk2116
Natsumi Noda, Tetsuya Ishimoto, Hisashi Mori, Takeaki Ozawa. Enhanced bioluminescent sensor for longitudinal detection of CREB activation in living cells. Photochemical & Photobiological Sciences. 2019. 18. 11. 2740-2747
Natsumi Noda, Takeaki Ozawa. Light-controllable Transcription System by Nucleocytoplasmic Shuttling of a Truncated Phytochrome B. Photochemistry and Photobiology. 2018. 94. 5. 1071-1076
Natsumi Noda, Raheela Awais, Robert Sutton, Muhammad Awais, Takeaki Ozawa. Dynamic monitoring of p53 translocation to mitochondria for the analysis of specific inhibitors using luciferase-fragment complementation. Biotechnology and Bioengineering. 2017. 114. 12. 2818-2827

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MISC (26)：

Natsumi Noda, Takeaki Ozawa. Development of CD44 bioluminescent sensors to detect the ectodomain cleavage and their application to breast cancer cells. 2023. 95. 1. 104-112
Bioluminescent sensor to analyze CD44s ectodomain cleavage in breast cancer cells. 2019. 42
CREB活性化を検出する生物発光プローブを用いた1細胞イメージング. 日本分子生物学会年会プログラム・要旨集(Web) (日本分子生物学会年会(Web)). 2018. 41
野田なつみ, Awais Raheela, Sutton Robert, Awais Muhammad, 小澤岳昌. p53のミトコンドリア移行をモニターする発光プローブの構築. 生命科学系学会合同年次大会. 2017. 2017年度. [1P-1418]
BAO Liang, INOUE Natsumi, KAWATA Shinya, MAKIGUCHI Yuma, ISHIBASHI Mitsuhiro, NODA Natsumi, ISHIKAWA Masaki, HIGA Takeshi, HIWATASHI Yuji, SEKINE Masami, et al. コケ類Physcomitrella patensにおけるPpCDKAは光反応を制御する. 2016. 57

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Books (1)：

PTSD: Brain Mechanisms and Clinical Implications.
Springer, Tokyo 2006

Professional career (1)：

博士(医学) (北海道大学)

Association Membership(s) (2)：

European Association for Cancer Research , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN

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