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J-GLOBAL ID:201401029231008094   Update date: Feb. 03, 2025

Yoshitomi Hiroyuki

ヨシトミ ヒロユキ | Yoshitomi Hiroyuki
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Affiliation and department:
Research field  (1): Immunology
Research theme for competitive and other funds  (12):
  • 2021 - 2024 Investigation of B-cell immunity against gynecological cancer and new strategies for diagnosis and treatment
  • 2020 - 2024 がん微小環境におけるCXCL13産生T細胞解析を起点としたヒトがん免疫機構解明
  • 2019 - 2022 Investigation of temporospatial dynamics of Sox4 in the pathogenesis of RA
  • 2018 - 2021 Comprehensive understanding of spatio-temporal effects of mutant IDH1 during the development of cartilage forming tumors
  • 2018 - 2021 Mechanism analysis of heterotopic ossification formation in Fibrodysplasia Ossificans Progressiva (FOP)
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Papers (109):
  • Haruka Suzuki, Kohei Hamada, Junzo Hamanishi, Akihiko Ueda, Ryusuke Murakami, Mana Taki, Rin Mizuno, Koichi Watanabe, Hanako Sato, Yuko Hosoe, et al. Artificial intelligence-based spatial analysis of tertiary lymphoid structures and clinical significance for endometrial cancer. Cancer Immunology, Immunotherapy. 2025. 74. 3
  • Haruka Suzuki, Kohei Hamada, Junzo Hamanishi, Akihiko Ueda, Ryusuke Murakami, Mana Taki, Rin Mizuno, Koichi Watanabe, Hanako Sato, Yuko Hosoe, et al. Artificial intelligence-based spatial analysis of tertiary lymphoid structures and clinical significance for endometrial cancer. Cancer immunology, immunotherapy : CII. 2025. 74. 3. 84-84
  • Akiko Oguchi, Akari Suzuki, Shuichiro Komatsu, Hiroyuki Yoshitomi, Shruti Bhagat, Raku Son, Raoul Jean Pierre Bonnal, Shohei Kojima, Masaru Koido, Kazuhiro Takeuchi, et al. An atlas of transcribed enhancers across helper T cell diversity for decoding human diseases. Science (New York, N.Y.). 2024. 385. 6704. eadd8394
  • Hirotsugu Oda, Kalpana Manthiram, Pallavi Pimpale Chavan, Eva Rieser, Önay Veli, Öykü Kaya, Charles Rauch, Shuichiro Nakabo, Hye Sun Kuehn, Mariël Swart, et al. Biallelic human SHARPIN loss of function induces autoinflammation and immunodeficiency. Nature immunology. 2024. 25. 5. 764-777
  • Hiroyuki Yoshitomi. Peripheral helper T cells, mavericks of peripheral immune responses. International immunology. 2024. 36. 1. 9-16
more...
MISC (129):
Books (8):
  • ポストGWAS時代の遺伝統計学 : オミクス解析と機械学習でヒト疾患を俯瞰する
    羊土社 2023 ISBN:9784758104104
  • 自己免疫疾患 : 層別化する新時代へ : 臨床検体のマルチオミクス解析、腸内細菌によって見えてきた免疫経路の全容
    羊土社 2022 ISBN:9784758104050
  • 夜明けを迎えたヒト免疫学
    羊土社 2022 ISBN:9784758125512
  • 臨床医が知っておくべき免疫学のいま
    医歯薬出版 2021
  • 難治性免疫疾患 病態解明と新規治療戦略
    医学のあゆみ・医歯薬出版 2021
more...
Lectures and oral presentations  (24):
  • 微量検体を用いたシングルセル免疫解析の実際
    (第50回日本免疫学会 2021)
  • 関節リウマチにおけるヒトT細胞の分化と機能
    (第8回JCRベーシックリサーチカンファレンス 2021)
  • ヒト自己免疫疾患におけるTph細胞
    (第64回日本リウマチ学会総会・学術集会 2020)
  • 異所性リンパ濾胞におけるヘルパーT細胞の病態機構
    (第6回T-cell seminar 2019)
  • Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments
    (令和元年日本リウマチ財団学術助成受賞者記念講演 2019)
more...
Awards (1):
  • 2019/06 - Japan Rheumatism Foundation Novartis medical award in rheumatoid arthritis Human Sox4 facilitates the development of CXCL13-producing helper T cells in inflammatory environments
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