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J-GLOBAL ID:201401037262479497   Update date: Dec. 19, 2024

Nakae Dai

ナカエ ダイ | Nakae Dai
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Affiliation and department:
Job title: Professor
Homepage URL  (1): http://kaken.nii.ac.jp/d/r/90207712.ja.html
Research field  (6): Other ,  Other ,  Other ,  Hygiene and public health (non-laboratory) ,  Nutrition and health science ,  Experimental pathology
Research keywords  (24): food factor ,  toxicologic pathology ,  Preventive Medicine ,  Animal Preventive Medicine ,  safety asessment ,  risk analysis ,  preneoplastic lesion ,  gene mutation ,  oxidative stress ,  choine-deficient, methionine-lowered, L-amino acid-defined diet ,  epigenetic carcinogenesis ,  species difference ,  gpt delta transgenic animal ,  endogenous carcinogenesis ,  8-oxoguanine ,  heterocyclicamine ,  nitroso compound ,  environmental carcinogen ,  genetically modified animal ,  diethylnitrosamine ,  chemical caricnogenesis ,  environmental factor ,  carcinogen ,  toxicology
Research theme for competitive and other funds  (5):
  • 2005 - 2009 がん研究の資材有効保存と利用に関する研究
  • 2004 - 2005 Study on the Mechanisms Underlying Endogenous Hepatocarcinogenesis Induced Only by the Manipulation of Food Composition
  • 1996 - 1999 Risk Assessment of Carcinogenesis due to Environmental Agents
  • 1996 - 1999 Basic Research on the Development and Progression of Pancreatic Duct Adenocarcinoma
  • 1992 - 1992 ラット肝における酸化性DNA障害依存性発癌機構と肝細胞壊死
Papers (221):
  • Takayuki Anzai, Glenn J Myatt, Frances Hall, Brenda Finney, Kenshi Nakagawa, Hijiri Iwata, Reo Anzai, Anne Dickinson, Matthew Freer, Dai Nakae, et al. Drug review process advancement and required manufacturer and contract research oraganization responses. Journal of toxicologic pathology. 2024. 37. 2. 45-53
  • Keiichi Ohata, Takeshi Sugaya, Hanh Nhung Nguyen, Karin Arai, Yuri Hatanaka, Kinuko Uno, Marika Tohma, Teppei Uechi, Keita Sekiguchi, Tsuyoshi Oikawa, et al. Urinary liver-type fatty acid binding protein is a biomarker reflecting renal damage and the ameliorative effect of drugs at an early stage of histone-induced acute kidney injury. Nephrology. 2023. 29. 3. 117-125
  • Motoki Hojo, Ai Maeno, Yoshimitsu Sakamoto, Yukio Yamamoto, Yuhji Taquahashi, Akihiko Hirose, Jin Suzuki, Akiko Inomata, Dai Nakae. Time-Course of Transcriptomic Change in the Lungs of F344 Rats Repeatedly Exposed to a Multiwalled Carbon Nanotube in a 2-Year Test. Nanomaterials (Basel, Switzerland). 2023. 13. 14
  • Keiichi Ohata, Takeshi Sugaya, Hanh Nhung Nguyen, Yuri Hatanaka, Kinuko Uno, Marika Tohma, Tsuyoshi Oikawa, Hiroshi Nagabukuro, Kanako Kuniyeda, Atsuko Kamijo-Ikemori, et al. Urinary liver-type fatty acid binding protein is increased in the early stages of the disease with a risk of acute kidney injury induced by histone. Nephrology (Carlton, Vic.). 2023. 28. 6. 345-355
  • Noriko Suzuki-Kemuriyama, Akari Abe, Sae Nakane, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae. Nonalcoholic steatohepatitis-associated hepatocarcinogenesis in mice fed a modified choline-deficient, methionine-lowered, L-amino acid-defined diet and the role of signal changes. PloS one. 2023. 18. 8. e0287657
more...
MISC (48):
  • Noriko Kemuriyama, Akari Abe, Megumi Yuki, Kinuko Uno, Sae Nakane, Katsuhiro Miyajima, Dai Nakae. Hepatocarcinogenesis associated with NASH in mice fed a CDAA-HF-T(-) and the involvement of the signal factors. CANCER SCIENCE. 2022. 113. 558-558
  • Noriko Suzuki-Kemuriyama, Akari Abe, Kinuko Uno, Shuji Ogawa, Atsushi Watanabe, Ryuhei Sano, Megumi Yuki, Katsuhiro Miyajima, Dai Nakae. A trans fatty acid substitute enhanced development of liver proliferative lesions induced in mice by feeding a cholinedeficient, methionine-lowered, L-amino acid-defined, high-fat diet (vol 19, 251, 2020). LIPIDS IN HEALTH AND DISEASE. 2022. 21. 1
  • Mandai K, Miyajima K, Kitamura S, Yamaguchi A, Uno K, Kuroki F, Nishida M, Shirasaka K, Tsustui T, Muro Y, et al. Effect of high fat diet on liver in db/db and KK-Ay mice. 2021. 46. Suppl. S109-S110
  • 山口彩音, 美谷島克宏, 宇野絹子, 杉本実紀, 黒木楓子, 西田芽衣, 小郷智記, 煙山紀子, 篠原雅巳, 中江大, et al. 2型糖尿病モデルdb/dbおよびKK-Ayマウスの腎臓における高脂肪食摂餌の影響. The Journal of Toxicological Sciences. 2020. 45. Suppl. S103-S103
  • Noriko Kemuriyama, Satomi Uchino, Syunta Sato, Haruka Funamizu, Linfeng Gao, Kanjiro Ryuu, Kinuko Uno, Soon Hui Teoh, Syuuji Ogawa, Atsushi Watanabe, et al. Development of an animal hepatocarcinogenesis model through non-obese (Asian-type) nonalcoholic steatohepatitis (NASH). CANCER SCIENCE. 2018. 109. 1041-1041
more...
Books (2):
  • 図で見る公衆衛生学
    学術研究出版/ブックウエイ 2017 ISBN:9784865842227
  • 図で見る公衆衛生学
    学術研究出版/ブックウエイ 2015 ISBN:9784865840254
Professional career (1):
  • D.M.Sc. (Nara Medical University)
Work history (2):
  • 2022/04 - 現在 Teikyo Heisei University Animal Medical Course, Department of Medical Sports, Faculty of Health Care and Medical Sports Professor
  • 2015/04 - 2022/03 Tokyo University of Agriculture Laboratory of Food Safety Assessment Science, Department of Nutritional Science and Food Safety, Faculty of Applied Biosciences Professor
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