Rchr
J-GLOBAL ID：201401039001794673   Update date: Feb. 27, 2024

Fujiwara Ikuko

フジワラ イクコ | Fujiwara Ikuko
Affiliation and department：
Nagaoka University of Technology Graduate School of Engineering, Department of Materials Sciences and Bioengineering

About Nagaoka University of Technology Graduate School of Engineering, Department of Materials Sciences and Bioengineering


Job title： Assoc. Prof.
Homepage URL  (1)： http://bio.nagaokaut.ac.jp/~honda-l/
Research field  (2)： Cell biology ,  Biophysics
Research keywords  (7)： Polymerization and depolymerization dynamics of actin ,  Cytoskeleton ,  Cell motility ,  MreB ,  Foce generation ,  protein theymodynamics ,  Biophysics
Research theme for competitive and other funds  (5)：
  • 2020 - 2023 TIRF visualization of the polymerization dynamics of bacterial actin cytoskeleton, MreB and A22 driven disruption mechanism
  • 2019 - 2021 Visualization of fluorescent labeled proteins required for helical-shaped bacterial swimming motility and the force propagation
  • 2017 - 2020 ゲルゾリン様タンパク質によるアクチン繊維切断機構の解明
  • 2015 - 2017 細胞伸張制御におけるアクチン重合調節タンパク質CPの役割
  • 2001 - 2002 単一アクチンフィラメント直視による重合・脱重合ダイナミクス機構の解明
Papers (34)：
  • Daichi Takahashi, Makoto Miyata, Ikuko Fujiwara. Assembly properties of bacterial actin MreB involved in Spiroplasma swimming motility. The Journal of biological chemistry. 2023. 299. 6. 104793-104793
  • Kazuto Tsukita, Manabu Kitamata, Hiroka Kashihara, Tomoki Yano, Ikuko Fujiwara, Timothy F Day, Tatsuya Katsuno, Jaewon Kim, Fumiko Takenaga, Hiroo Tanaka, et al. Phase separation of an actin nucleator by junctional microtubules regulates epithelial function. Science advances. 2023. 9. 7. eadf6358
  • Daichi Takahashi, Ikuko Fujiwara, Makoto Miyata. Purification and ATPase Activity Measurement of Spiroplasma MreB. Methods in molecular biology (Clifton, N.J.). 2023. 2646. 359-371
  • Yusuke Kanematsu, Akihiro Narita, Toshiro Oda, Ryotaro Koike, Motonori Ota, Yu Takano, Kei Moritsugu, Ikuko Fujiwara, Kotaro Tanaka, Hideyuki Komatsu, et al. Structures and mechanisms of actin ATP hydrolysis. Proceedings of the National Academy of Sciences of the United States of America. 2022. 119. 43. e2122641119
  • Daichi Takahashi, Ikuko Fujiwara, Yuya Sasajima, Akihiro Narita, Katsumi Imada, Makoto Miyata. ATP-dependent polymerization dynamics of bacterial actin proteins involved in Spiroplasma swimming. Open biology. 2022. 12. 10. 220083-220083
ｍore...
MISC (5)：
  • 武田修一, 兼松佑典, 成田哲博, 田中康太郎, 小池亮太郎, 太田元規, 鷹野優, 森次圭, 藤原郁子, 渡邉信久, et al. F-form actin structure at an atomic resolution: how the molecular assembly and the ATP hydrolysis are coupled. 日本物理学会講演概要集(CD-ROM). 2020. 75. 1
  • 武田修一, 藤原郁子, 小田俊郎, 成田哲博, 前田雄一郎. ラトランキュリンAはF型からG型へのコンフォメーション変化を誘起しアクチン脱重合を促進する. 日本結晶学会年会講演要旨集. 2019. 2019
  • 武田修一, 成田哲博, 小田俊郎, 田中康太郎, 小池亮太郎, 太田元規, 藤原郁子, 渡邉信久, 渡邉信久, 前田雄一郎. 高分解能X線結晶構造から明らかとなったアクチン重合・ATP加水分解機構. 日本結晶学会年会講演要旨集. 2017. 2017
  • Fujiwara, I, S Suetsugu, S Uemura, H Miki, T Takenawa, S Ishiwata. Direct observation of branching in actin filaments triggered by Arp2/3 complex. BIOPHYSICAL JOURNAL. 2002. 82. 1. 385A-385A
  • Fujiwara, I, S Takahashi, H Tadakuma, T Funatsu, S Ishiwata. Microscopic analysis of polymerization process of single actin filaments. BIOPHYSICAL JOURNAL. 2001. 80. 1. 94A-94A
Books (1)：
  • 一分子生物学
    同仁化学出版 2014
Lectures and oral presentations  (76)：
  • Purification and characterization of bacterial actin MreB1: a component of swimming machinery in Spiroplasma
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
  • Measurement of motor protein ATPase and binding dissociation by QCM
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
  • Understanding the orientation of actin subunits by conjugating with jasplakinolide or phalloidin through FRET observation
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
  • QCM may detect changes in actin filaments brought by the association and dissociation of myosin
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
  • Allosteric inhibitory mechanisms of actin polymerization by;cytochalasin D
    (The 61st Annual Meeting of the Biophysical Society of Japan 2023)
ｍore...
Education (2)：
  • 1998 - 2003 Graduate school of science, Waseda University, Japan Graduate School, Division of Science and Engineering Dept. of Physics
  • - 1998 Waseda University Faculty of Science and Engineering Dept of Applied Physics
Professional career (1)：
  • 博士(理学) (早稲田大学)
Work history (8)：
  • 2022/04 - 現在 Nagaoka University of Technology Graduate School of Engineering, Department of Materials Sciences and Bioengineering Assoc. Prof.
  • 2021/04 - 2022/03 Nagaoka University of Technology Graduate School of Engineering Department of Bioengineering Assoc. Prof.
  • 2019/04 - 2021/03 Osaka City University Graduate School of Science Biology and Geosciences Course Assistant Professor
  • 2015/01/01 - 2019/03/31 Nagoya Institute of Technology Reasearch Admistration Office University Research Administrator (Research Assistant Professor)
  • 2014/04/01 - 2014/12/31 Institute for Integrated Cell-Material Sciences, Kyoto University Assistant Professor
Show all
Committee career (5)：
  • 2022/01 - 2024/12 The Biophysical Society of Japan Editorial board member
  • 2021/01 - 2021/12 Biophysical society of Japan 分野別専門委員 (アクチン)
  • 2020/01 - 2020/12 Biophysical society of Japan 分野別専門委員 (細胞骨格)
  • 2018/01 - 2018/12 名古屋工業大学ダイバーシティ推進センター スーパーバイザー
  • 2016/11 - 2017/11 American Society For Cell Biology (ASCB) 名古屋工業大学 アンバサダー
Awards (1)：
  • 2018/10 - Faculty of 1000 Ltd | Science Navigation Group Recommended in F1000Prime as being of special significance in its field by F1000 Latrunculin A accelerates actin filament depolymerization in addition to sequestering actin monomers
Association Membership(s) (4)：
The Molecular Biology Society of Japan ,  The American Society for Cell Biology ,  Japan Society for Cell Biology ,  The Biophysical Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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