Research theme for competitive and other funds (4):
2022 - 2025 幹細胞が持つ特性を利用した新規分化誘導方法の確立
2012 - 2014 マウス生体由来多能性幹細胞(Muse細胞)の発生学的解析
マウス間葉系組織に存在する多能性幹細胞(Muse細胞)の特異的マーカーの探索
ヒト生体由来多能性幹細胞 Muse細胞を用いた劇症肝炎の治療開発と組織修復機構の解明
Papers (74):
Makoto Takahashi, Yoshihiro Kushida, Yasumasa Kuroda, Shohei Wakao, Yasuhiro Horibata, Hiroyuki Sugimoto, Mari Dezawa, Yoshikatsu Saiki. Structural reconstruction of mouse acute aortic dissection by intravenously administered human Muse cells without immunosuppression. Communications medicine. 2024. 4. 1. 174-174
Masayuki Otani, Yoshihiro Kushida, Yasumasa Kuroda, Shohei Wakao, Yo Oguma, Keisuke Sasaki, Shintaro Katahira, Ryohei Terai, Rie Ryoke, Hiroi Nonaka, et al. New rat model of spinal cord infarction with long-lasting functional disabilities generated by intraspinal injection of endothelin-1. Stroke and Vascular Neurology. 2024. svn-2023
Gen Li, Shohei Wakao, Masaaki Kitada, Mari Dezawa. Tumor suppressor let-7 acts as a key regulator for maintaining pluripotency gene expression in Muse cells. 2023
Yo Oguma, Yasumasa Kuroda, Shohei Wakao, Yoshihiro Kushida, Mari Dezawa. Single-cell RNA sequencing reveals different signatures of mesenchymal stromal cell pluripotent-like and multipotent populations. iScience. 2022. 25. 11. 105395-105395
Eiji Ogawa, Yo Oguma, Yoshihiro Kushida, Shohei Wakao, Kana Okawa, Mari Dezawa. Naïve pluripotent-like characteristics of non-tumorigenic Muse cells isolated from human amniotic membrane. Scientific reports. 2022. 12. 1. 17222-17222