2022 - 2026 Basic research on the development of periodontal tissue regenerative implants using titanium-binding proteins and cytokines
2019 - 2024 Bone and tooth differentiation induced by BMP and rapamycin
2020 - 2023 Root-caries repair agent developed using reverse phase transformation from apatite to octacalcium phosphate
2020 - 2023 Development of next-generation dental implant material zirconia regenerating periodontal tissue
2019 - 2022 The study of bone matrix-derived TGF-beta that acts as a bone coupling factor
2019 - 2022 A mechanism of osteoblastic cells adhesion and characterization of precipitated crystals induced by a novel dental implant material Ce-TZP/Al2O3
2015 - 2017 Differentiation potential of osteoblast from cultured C2C12 cells on zirconia disk.
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Papers (21):
Saito, M.M., Onuma, K., Yamakoshi, Y. Nanoscale osseointegration of zirconia evaluated from the interfacial structure between ceria-stabilized tetragonal zirconia and cell-induced hydroxyapatite. Journal of Oral Biosciences. 2024. 66. 2
Mari M. Saito, Kazuo Onuma, Yasuo Yamakoshi. Cementum is key to periodontal tissue regeneration: A review on apatite microstructures for creation of novel cementum-based dental implants. genesis. 2023. 61. 3-4. e23514
Yasuo Yamakoshi, Risako Chiba-Ohkuma, Yukihiko Hidaka, Kazuo Onuma, Ryuji Yamamoto, Mari M Saito, Takeo Karakida. Repurposing MDZ as a tool for tissue regeneration in dental cells. Journal of oral biosciences. 2022. 64. 1. 37-42
Kazuo Onuma, Mari M Saito, Yasuo Yamakoshi, Mayumi Iijima, Yu Sogo, Koichi Momma. Coherent surface structure induces unique epitaxial overgrowth of metastable octacalcium phosphate on stable hydroxyapatite at critical fluoride concentration. Acta biomaterialia. 2021. 125. 333-344
Mari M Saito, Kazuo Onuma, Ryuji Yamamoto, Yasuo Yamakoshi. New insights into bioactivity of ceria-stabilized zirconia: Direct bonding to bone-like hydroxyapatite at nanoscale. Materials science & engineering. C, Materials for biological applications. 2021. 121. 111665-111665
唐木田丈夫, 日高亨彦, 小沼一雄, 山本竜司, 斉藤まり, 千葉(大熊)理紗子, 山越康雄. Drug Repositioning Efficacy of Midazolam on Hard Tissue Forming Cells. Journal of Oral Biosciences Supplement (Web). 2020. 2020
日高亨彦, 大熊理紗子, 唐木田丈夫, 山本竜司, 阿部佳子, 斉藤まり, 山越康雄, 河原博. Drug repositioning of midazolam in the induction of differentiation from C2C12 cells to osteoblasts. Journal of Oral Biosciences Supplement (Web). 2020. 2020
2010 - 2014 Tsurumi University Graduate School of Dental Medicine Doctor of Philosophy in Dental Science [Ph.D.(D.Sc.)]
2003 - 2009 Tsurumi University School of Dental Medicine
Professional career (1):
博士(歯学) (鶴見大学)
Work history (4):
2018/04 - 現在 Tsurumi University School of Dental Medicine
2015/04 - 2018/03 Tsurumi University School of Dental Medicine
2016 - 2016 University of Michigan School of Dentistry Department of Biologic Materials and Sciences Academic Affiliate
2014/04 - 2015/03 Tsurumi University School of Dental Medicine
Awards (1):
2022/09 - JAOB/Rising Members Award New insights into bioactivity of ceria-stabilized zirconia: Direct bonding to bone-like hydroxyapatite at nanoscale