Kobori Takuro

コボリタクロウ | Kobori Takuro

Affiliation and department：
Job title： Lecturer

Research field (4)： Fetal medicine/Pediatrics , Tumor diagnostics and therapeutics , Pharmacology , Clinical pharmacy

Research keywords (8)： Pediatric cancer , Ovarian Clear Cell Carcinoma , Glioblastoma , Adolescent and Young Adult , Scaffold Protein Ezrin/Radixin/Moesin , Immune Checkpoint Molecule , 核酸医薬品 , cancer immunotherapy

Research theme for competitive and other funds (16)：

2024 - 2026 Development of a novel immune checkpoint blockade therapy targeting the intracellular scaffold protein for ovarian clear cell carcinoma common in Japanese women
2024 - 2025 .
2024 - 2025 Development of macrophage immune checkpoint blockade therapy for the refractory glioblastoma.
2023 - 2024 .
2023 - 2024 Development of innate immune checkpoint blockade therapy for ovarian clear cell adenocarcinoma

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Papers (48)：

Takuro Kobori, Mikiko Sugimoto, Takuya Ito, Kikuko Hotta. Involvement of Intracellular Scaffold Proteins in the Expression of Immune Checkpoint Molecule PD-L1 and Prognosis in Patients with Glioblastoma. Journal of AYA Oncology Alliance. 2024. 4. 2. 35-45
Takuro Kobori, Yui Ito, Chihiro Tanaka, Yoko Urashima, Tomoyo Yamamura, Nobumasa Takagaki, Tokio Obata. Changes in the macrophage polarization status and the kinetics of immune-related factors in the ascites of patients with pancreatic cancer before and after cell-free and concentrated ascites reinfusion therapy. Japanese Journal of Community Medicine and Pharmaceutical Sciences. 2024. 11. 1. 35-45
Takuro Kobori, Yui Ito, Yoko Urashima, Takuya Ito, Tokio Obata. Modulation of Immune Checkpoint Molecule PD-L1 Expression via Scaffold Proteins in the Ovarian Clear Cell Carcinoma Common in Japanese Women. Journal of AYA Oncology Alliance. 2024. 4. 1. 1-8
Suguru Kurokawa, Takuro Kobori, Masato Yoneda, Yuji Ogawa, Yasushi Honda, Takaomi Kessoku, Kento Imajo, Satoru Saito, Atsushi Nakajima, Kikuko Hotta. Identification of differentially methylated regions associated with both liver fibrosis and hepatocellular carcinoma. BMC gastroenterology. 2024. 24. 1. 57-57
Yui Ito, Takuro Kobori, Yoko Urashima, Takuya Ito, Kikuko Hotta, Tokio Obata. Moesin affects the plasma membrane expression and the immune checkpoint function of CD47 in human ovarian clear cell carcinoma. Journal of Reproductive Immunology. 2024. 161. 104185

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MISC (53)：

小堀宅郎, 伊藤優衣, 田中千都, 浦嶋庸子, 山村智代, 高垣伸匡, 小畑友紀雄. 腹水濾過濃縮再静注法の施行前後における膵臓癌患者の腹水中免疫微小環境の解析. 日本在宅薬学会学術大会プログラム・講演抄録集. 2023. 16回. 166-166
岩永菜那, 浦嶋庸子, 浦嶋和也, 鈴木薫, 小堀宅郎, 小畑友紀雄. 経腸栄養剤および経腸栄養食品が消化管からのタクロリムス吸収におよぼす影響. TDM研究. 2023. 40. 2. 182-182
吉田愛, 河村拓実, 大塚雄也, 浦嶋庸子, 浦嶋和也, 鈴木薫, 小堀宅郎, 小畑友紀雄. 糖質および食物繊維がラットの血中バルプロ酸ナトリウム濃度におよぼす影響. TDM研究. 2023. 40. 2. 203-203
菊地理友, 川口葵, 末光優香, 浦嶋庸子, 浦嶋和也, 鈴木薫, 小堀宅郎, 小畑友紀雄. Caco-2単層細胞膜におけるカルバマゼピン透過性に対する経腸栄養剤中の未消化および消化後タンパクの影響. TDM研究. 2023. 40. 2. 204-204
伊藤優衣, 小堀宅郎, 田中千都, 浦嶋庸子, 伊藤卓也, 高垣伸匡, 小畑友紀雄. Involvement of Ezrin/Radixin/Moesin in the cell surface expression of immune checkpoint molecule PD-L1 in human endometrial carcinoma cell line. 日本薬学会年会要旨集(Web). 2023. 143rd

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Patents (2)：

コンドロイチン硫酸生合成を阻害するアンチセンス核酸
REGULATOR OF EXPRESSION AND/OR FUNCTION OF SCN1A GENE

Education (3)：

2011 - 2014 Kobe Gakuin University Graduate School of Food and Pharmaceutical Sciences
2009 - 2011 Tohoku Pharmaceutical University Graduate School of Pharmaceutical Sciences
2005 - 2009 Tohoku Pharmaceutical University Faculty of Pharmacy

Professional career (1)：

Ph.D. (Kobe Gakuin University)

Work history (7)：

2023/07 - 現在 Graduate School of Pharmaceutical Sciences, Osaka Ohtani University
2023/07 - 現在 Faculty of Pharmacy, Osaka Ohtani University Laboratory of Pathophysiology and Pharmacotherapeutics Lecturer
2020/08 - 2023/06 Osaka Ohtani University Faculty of Phamacy Assistant Professor
2019/08 - 2020/07 大阪大学大学院薬学研究科
2019/04 - 2020/07 ルクサナバイオテク株式会社研究開発部

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Awards (10)：

2023/07 - The Japanese Association of Home Care Pharmacies Best Presentation Award in The 16th Congress of The Japanese Association of Home Care Pharmacies Analysis for Ascitic Immune Microenvironment in Patients with Pancreatic Cancer Receiving Before and After CART
2016 - The Japanese Society for the Study of Xenobiotics DMPK Editors’ Award for the Most Excellent Article in 2014 2nd place
2014/03 - 日本薬学会日本薬学会第 134 年会優秀発表賞
2013/09 - 日本緩和医療薬学会第 7 回日本緩和医療薬学会年会優秀発表賞
2013/08 - 日本薬学会薬理系薬学部会生体機能と創薬シンポジウム 2013 優秀発表賞

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Association Membership(s) (7)：

The Japanese Association of Home Care Pharmacies , AYA Oncology Alliance , THE JAPANESE PHARMACOLOGICAL SOCIETY , THE PHARMACEUTICAL SOCIETY OF JAPAN , 日本医療薬学会 , The Pharmacy Society of Japan , THE JAPANESE SOCIETY OF TOXICOLOGY

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