Rchr
J-GLOBAL ID：201501003117177136
Update date: Apr. 30, 2024
Sakamoto Akihiko
サカモト アキヒコ | Sakamoto Akihiko
Affiliation and department：
Job title：
Assistant professor
Research field (4)：
Immunology
, Virology
, Hematology and oncology
, Biophysics
Research keywords (13)：
Antigen presentation
, Acquired immunity
, Germinal center
, Immunological memory
, Antibody
, B cell
, T cell
, Mouse
, Vaccine
, SARS-CoV-2
, Streptococcus pneumoniae
, Lymphoma
, Single-molecule imaging
Research theme for competitive and other funds (4)：
- 2022 - 2025 Versatile next-generation vaccine platform -Application for COVID-19-
- 2021 - 2024 Development of a novel COVID-19 vaccine using heterologous virus vectors
- 2018 - 2020 Study of the roles of Zizimin2 in mouse B cells for prevention of the elderly from infectious diseases
- 2014 - 2016 Comparison of tumor cells and microenvironmental cells for novel therapies targeting microenvironments in malignant lymphoma
Papers (18)：
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Yutaro Yamamoto, Camila Fabbri, Daiki Okuhara, Rina Takagi, Yuna Kawabata, Takuto Katayama, Mitsuhiro Iyori, Ammar A. Hasyim, Akihiko Sakamoto, Hiroaki Mizukami, et al. A two-dose viral-vectored Plasmodium vivax multistage vaccine confers durable protection and transmission-blockade in a pre-clinical study. Frontiers in Immunology. 2024. 15. 1372584
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Sitti Nurisyah, Mitsuhiro Iyori, Ammar A. Hasyim, Akihiko Sakamoto, Hinata Hashimoto, Kyouhei Yamagata, Saya Yamauchi, Khaeriah Amru, Kartika H. Zainal, Irfan Idris, et al. Comparison between neutralization capacity of antibodies elicited by COVID-19 natural infection and vaccination in Indonesia: A prospective cohort. Antibodies. 2023. 12. 3. 60
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Satomi Sahashi, Kazuyuki Shimada, Yusuke Takagi, Tomohiro Aoki, Shunsuke Kunou, Akihiko Sakamoto, Atsushi Murase, Katsuya Furukawa, Yusuke Kagaya, Yusuke Yamaga, et al. Clinicopathological characteristics associated with the engraftment of patient lymphoma cells in NOG mice. International Journal of Hematology. 2023. 118. 221-230
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Ammar A. Hasyim, Mitsuhiro Iyori, Tetsushi Mizuno, Yu-ichi Abe, Iroha Yamagoshi, Yenni Yusuf, Intan Syafira, Akihiko Sakamoto, Yutaro Yamamoto, Hiroaki Mizukami, et al. Adeno-associated virus-based malaria booster vaccine following attenuated replication-competent vaccinia virus LC16m8Δ priming. Parasitology International. 2023. 92. 102652
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Akihiko Sakamoto, Hiroaki Osawa, Hinata Hashimoto, Tetsushi Mizuno, Ammar A. Hasyim, Yu-ichi Abe, Yuto Okahashi, Ryohei Ogawa, Mitsuhiro Iyori, Hisatoshi Shida, et al. A replication-competent smallpox vaccine LC16m8Δ-based COVID-19 vaccine. Emerging Microbes & Infections. 2022. 11. 1. 2359-2370
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MISC (10)：
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Mitsuo Maruyama, Akihiko Sakamoto, Yuji Morita, Akinori Takaoka. Immunosenescence: the forefront of infection and trophic control. Yakugaku Zasshi. 2020. 140. 3. 391-393
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坂本 明彦, 丸山 光生. 基礎老化研究の最前線と健康長寿社会の取り組み. 加齢皮膚医学セミナー. 2018. 13. 1. 1-4
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坂本 明彦, 丸山 光生. 細胞老化と個体老化. 病理と臨床. 2018. 36. 2. 98-101
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坂本 明彦, 船津 高志. 全反射蛍光顕微鏡による細胞膜受容体MPL二量体の1分子イメージング. 生体の科学. 2017. 68. 5. 384-385
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Tomohiro Aoki, Kazuyuki Shimada, Akihiko Sakamoto, Keiki Sugimoto, Takanobu Morishita, Yuki Kojima, Satoko Shimada, Seiichi Kato, Chisako Iriyama, Shunsuke Kuno, et al. Emetine Elicits Apoptosis of Intractable B-Cell Lymphoma Cells with MYC Rearrangement through Inhibition of Glycolytic Metabolism. Blood. 2016. 128. 22
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Patents (1)：
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Stromal cells derived from lymph nodes of patients with blood related diseases
Books (1)：
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決定版 阻害剤・活性化剤ハンドブック
羊土社 2019 ISBN:9784758120999
Lectures and oral presentations (87)：
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Development of the viral vectored COVID vaccine
(14th Life Science Research Exchange Seminar 2024)
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Development of the LC16m8Δ2 virus-vectored COVID vaccine
(The 135th Annual Meeting of The Pharmaceutical Society of Japan Hokuriku Branch 2023)
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Development of the multi-stage Plasmodium vivax vaccine
(The 135th Annual Meeting of The Pharmaceutical Society of Japan Hokuriku Branch 2023)
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P. falciparum-P. vivax bivalent vaccine development using LC16m8Δ/AAV viral vectors platform achieves sterile protection and transmission blocking
(ASTMH 2023 Annual Meeting 2023)
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Humoral immune responses to the central repeat region of PfCSP induced by a viral-vectored plasmodium falciparum vaccine play critical roles in protection in a murine model
(ASTMH 2023 Annual Meeting 2023)
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Education (4)：
- 2007 - 2010 The University of Tokyo Graduate School of Pharmaceutical Sciences Doctor of Pharmacy, Ph.D.
- 2005 - 2007 The University of Tokyo Graduate School of Pharmaceutical Sciences Master of Pharmacy
- 2003 - 2005 The University of Tokyo Faculty of Pharmaceutical Sciences Department of Pharmacy
- 2001 - 2003 The University of Tokyo College of Arts and Sciences Natural Sciences II
Professional career (1)：
- Ph.D. (The University of Tokyo)
Work history (6)：
- 2024/04 - 現在 Yamaguchi University Graduate School of Medicine Assistant Professor
- 2022/10 - 2024/03 Kanazawa University School of Pharmacy Assistant professor
- 2020/10 - 2022/09 Kanazawa University School of Pharmacy Postdoctoral researcher
- 2016/04 - 2020/10 National Center for Geriatrics and Gerontology Department of Mechanism of Aging Researcher
- 2013/10 - 2016/03 Nagoya University Graduate School of Medicine Researcher
- 2010/04 - 2013/09 The University of Tokyo Graduate School of Pharmaceutical Sciences Project Researcher
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Committee career (5)：
- 2023/11 - 現在 Vaccine: X Reviewer
- 2023/07 - 現在 Frontiers in Immunology Review Editor
- 2023/03 - 現在 Heliyon Reviewer
- 2023/04 - 2024/03 Kanazawa University Health and Safety Committee, Health Manager
- 2022/01 - 2023/03 第92回日本寄生虫学会大会 大会役員
Association Membership(s) (1)：
Japanese Society for Immunology
