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J-GLOBAL ID：201501003218735369 Update date: Nov. 25, 2024

Shimizu Mayuko

シミズマユコ | Shimizu Mayuko

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Affiliation and department：

Research field (3)： Experimental pathology , Laboratory animal science , Nutrition and health science

Research keywords (7)：経皮感作食物アレルギーモデル動物 , epicutaneous sensitization , food allergy , macrophage , 高脂肪コレステロール食 , 肝線維化モデル , NASHモデル

Research theme for competitive and other funds (3)：

2022 - 2025 Elucidation of the pathogenesis and new therapeutic strategies for brain- and gut-related steatohepatitis based on brain-derived neurotrophic factor
2020 - 2023 The role of macrophages in the progression of fibrosis of NASH and its regulation by nutritional factors
2017 - 2020 Search for functional ingredients and foods altering cholesterol-bile acid metabolism for prevention of NASH development

Papers (81)：

Masahiro Umemura, Akira Honda, Maho Yamashita, Takeshi Chida, Hidenao Noritake, Kenta Yamamoto, Takashi Honda, Mayuko Ichimura-Shimizu, Koichi Tsuneyama, Teruo Miyazaki, et al. High-fat diet modulates bile acid composition and gut microbiota, affecting severe cholangitis and cirrhotic change in murine primary biliary cholangitis. Journal of autoimmunity. 2024. 148. 103287-103287
Katsuhisa Omagari, Juna Ishida, Konomi Murata, Ryoko Araki, Mizuki Yogo, Bungo Shirouchi, Kazuhito Suruga, Nobuko Sera, Kazunori Koba, Mayuko Ichimura-Shimizu, et al. The Effect of Barley Bran Polyphenol-Rich Extracts on the Development of Nonalcoholic Steatohepatitis in Sprague-Dawley Rats Fed a High-Fat and High-Cholesterol Diet. Livers. 2024. 4. 2. 193-208
Mayuko Ichimura-Shimizu, Khuleshwari Kurrey, Misaki Miyata, Takuya Dezawa, Koichi Tsuneyama, Masami Kojima. Emerging Insights into the Role of BDNF on Health and Disease in Periphery. Biomolecules. 2024. 14. 4. 444-444
Honoka Tsunematsu, Masaki Imanishi, Yuka Uemura, Yoshiya Higaki, Miyu Morisaki, Akari Katsura, Licht Miyamoto, Masafumi Funamoto, Mayuko Ichimura-Shimizu, Yuya Horinouchi, et al. Indigo Leaves-Induced Pulmonary Arterial Remodeling without Right Ventricular Hypertrophy in Rats. Biological & pharmaceutical bulletin. 2024. 47. 7. 1350-1359
Takumi Kakimoto, Masato Hosokawa, Mayuko Ichimura-Shimizu, Hirohisa Ogawa, Yuko Miyakami, Satoshi Sumida, Koichi Tsuneyama. Accumulation of α-synuclein in hepatocytes in nonalcoholic steatohepatitis and its usefulness in pathological diagnosis. Pathology, research and practice. 2023. 247. 154525-154525

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MISC (24)：

菊池健太郎, 松本光太郎, 高井敦子, 清水真祐子, 守時由起, 常山幸一, 原眞純, 宮川浩. Gastrointestinal microbiome and non-alcoholic steatohepatitis. 月刊糖尿病・内分泌代謝科. 2021. 53. 3
Takai Atsuko, Kikuchi Kentaro, Ichimura Mayuko, Tsuneyama Koichi, Moritoki Yuki, Matsumoto Kotaro, Tsunashima Hiromichi, Onda Takeshi, Kuniyoshi Noriyuki, Nariyama Tomoyuki, et al. Fructo-oligosaccharides ameliorate steatohepatitis, visceral adiposity, and associated chronic inflammation via increased production of short-chain fatty acids in a mouse model of non-alcoholic steatohepatitis. BMC Gastroenterology. 2020. Vol.20. No.1. 46-46
Tsuneyama Koichi, Ichimura Mayuko, Oya Takeshi, Matsumoto Minoru, Kobayashi Tomoko, Ogawa Hirohisa, Nishitsuji Kazuchika, Yamashita Michiko. 肝臓病理所見のとり方とその解釈. 法医病理. 2019. Vol.25. No.1. 1-12
市村真祐子, 尾矢剛志, 小川博久, 大曲勝久, 常山幸一. 非アルコール性脂肪肝炎モデルマウスにおける肝線維化発症とコレステロール貪食マクロファージの関連. 日本病理学会会誌. 2019. 108. 1. 328-328
常山幸一, 市村真祐子. 免疫チェックポイント阻害薬による肝障害を来した4例の病理学的特徴. 肝臓. 2019. 60. Suppl.1. A331-A331

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Patents (1)：

肝の線維化を伴いえるNAFLDモデル動物、その作製方法、及びそれを作製する為の飼料

Books (1)：

Cell cycle regulation via the p53, PTEN, and BRCA1 tumor suppressors
InTech 2016

Lectures and oral presentations (40)：

実験計画法を用いた高感度2-ピコリルアミン誘導体化UHPLC-ESI-MS/MS法の開発: 血中短鎖脂肪酸測定への応用
(第31回クロマトグラフィー科学会議 2020)
A novel image analysis technology that can verify quantification and progress pattern of NASH fibrosis
(The Liver Meeting 2020 2020)
実験的モデル動物作成に用いられる高脂肪・コレステロール食に含まれるコール酸のNASH病態形成への影響
(第56回日本肝臓学会総会 2020)
Make a food-based healthy body to counter the unprecedented crisis
(第3回COI学術交流会 2020)
イメージング質量分析によるNASH線維化肝で増加する脂質の同定
(第109回日本病理学会総会 2020)

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Education (1)：

2015 - 長崎県立大学大学院人間健康科学研究科栄養科学専攻

Professional career (1)：

栄養学博士 (長崎県立大学大学院)

Work history (3)：

2018/02/01 - 着任
2018/02 - The University of Tokushima
Nara Women's University Faculty, Division of Human Life and Environmental Sciences

Awards (2)：

2020/06/19 - 徳島大学医学部学部長特別表彰医学科遠隔授業サポート
2020/03 - Committee of The 29th Asian Pacific Association for the Study of the Liver (APASL) 2020 Travel grant Phellodendron bark and its component berberine prevent nonalcoholic steatohepatitis-related fibrosis in mice

Association Membership(s) (7)：

The Japanese Society of Pathology , TSOD(肥満・糖尿病)マウス研究会 , The Japanese Society of Food & Nutrition , 日本栄養士会 , The Japanese Society of Nutrition and Dietetics , 日本栄養・食糧学会 , 日本肝臓学会

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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