Rchr
J-GLOBAL ID：201501010814159100   Update date: Aug. 08, 2024

Akikazu Murakami

ムラカミ アキカズ | Akikazu Murakami
Affiliation and department：
Tokushima university Department of Oral Microbiology, Institute of Biomedical Sciences

About Tokushima university Department of Oral Microbiology, Institute of Biomedical Sciences


Job title： Associate Professor
Research field  (3)： Immunology ,  Applied microbiology ,  Applied molecular and cellular biology
Research keywords  (6)： 抗体 ,  B細胞 ,  バクテリオファージ ,  ファージディスプレイ ,  VHH ,  単ドメイン抗体
Research theme for competitive and other funds  (6)：
  • 2020 - 2023 VHH抗体の欠点を克服するヘテロ2量体化「挟み込み」抗体の研究
  • 2019 - 2023 ファージワクチンの免疫応答誘導メカニズムの解明とB細胞移入療法への応用の試み
  • 2016 - 2019 Immunological mechanism for M13-phage-based vaccine immunogenicity and its application.
  • 2015 - 2018 Development of the rapid mass extraction system for adipose derived stem cells by using micro-patterned scaffold
  • 2015 - 2017 Single cell screening of the curvature recognition protein group using a 3D micropattern
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Papers (52)：
  • Yuka Hiroshima, Rie Kido, Jun-Ichi Kido, Mika Bando, Kaya Yoshida, Akikazu Murakami, Yasuo Shinohara. Synthesis of secretory leukocyte protease inhibitor using cell-free protein synthesis system. Odontology. 2024
  • Yasufumi Nishikawa, Yoritoki Tomotake, Hiromichi Kawano, Koji Naruishi, Jun-ichi Kido, Yuka Hiroshima, Akikazu Murakami, Tetsuo Ichikawa, Hiromichi Yumoto. Effects of Candidalysin Derived from Candida albicans on the Expression of Pro-Inflammatory Mediators in Human Gingival Fibroblasts. International Journal of Molecular Sciences. 2023. 24. 4. 3256-3256
  • Ryo Yonehara, Shigefumi Kumachi, Kenji Kashiwagi, Kanako Wakabayashi-Nakao, Maiko Motohashi, Taihei Murakami, Teruhiko Yanagisawa, Hidenao Arai, Akikazu Murakami, Yukio Ueno, et al. A novel agonist with homobivalent single-domain antibodies that bind the FGF receptor 1 domain III functions as an FGF2 ligand. The Journal of biological chemistry. 2023. 299. 2. 102804-102804
  • Yuta Uemura, Yuka Hiroshima, Ayano Tada, Keiji Murakami, Kaya Yoshida, Yuji Inagaki, Tomomi Kuwahara, Akikazu Murakami, Hideki Fujii, Hiromichi Yumoto. Porphyromonas gingivalis Outer Membrane Vesicles Stimulate Gingival Epithelial Cells to Induce Pro-Inflammatory Cytokines via the MAPK and STING Pathways. Biomedicines. 2022. 10. 10. 2643-2643
  • パレヴィ・ムハンマドレザ, 村上 圭史, 村上 明一, 藤猪 英樹. Autoinducer Analog-1(AIA-1)はpruRとPA0066-65-64の発現を介して緑膿菌の抗生物質耐性を低減する(Autoinducer Analog-1(AIA-1) decreases antibiotic tolerance of Pseudomonas aeruginosa through pruR and PA0066-65-64 expression). Journal of Oral Biosciences Supplement. 2022. 2022. 114-114
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MISC (85)：
  • 村上 明一, 塚原 成俊, 岸本 英博. 抗体開発の新潮流 高性能VHH抗体の迅速開発プラットフォーム. 日本生化学会大会プログラム・講演要旨集. 2022. 95回. 3S11m-01
  • 赤嶺 佐月, 村上 明一, 塚原 成俊, 喜友名 しのぶ, 岸本 英博. VHH抗体の迅速かつ簡便な新規親和性向上法の開発研究. 琉球医学会誌. 2021. 40. 1-4. 74-74
  • 山城 美羽, 村上 明一, 喜友名 しのぶ, 塚原 成俊, 中島 雄介, 岸本 英博. アフリカ豚熱(ASF)に有効なサブユニットワクチン候補蛋白質の検証. 琉球医学会誌. 2021. 40. 1-4. 76-76
  • KIYUNA Shinobu, MURAKAMI Akikazu, TSUKAHARA Narutoshi, FUJII Hideki, KISHIMOTO Hidehiro. Analysis of the contribution of VHH antibody framework regions to antigen binding. 日本免疫学会総会・学術集会記録(CD-ROM). 2021. 50
  • 井上暁人, 安田貴信, 北口哲也, 村上明一, 上田宏. Development of selection method for a nanobody-based fluorescent immunosensor “mini Q-body” by yeast surface display. 日本生物工学会大会講演要旨集. 2021. 73rd
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Patents (6)：
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Books (1)：
  • 食物アレルギーの現状とリスク低減化食品素材の開発
    シーエムシー出版 2021 ISBN:9784781315799
Professional career (1)：
  • 博士(理学) (東京理科大学)
Work history (2)：
  • 2021/07 - 現在 Tokushima university
  • 2013/12 - 2021/06 University of the Ryukyus
Committee career (1)：
  • 2022/04 - 現在 The antibody society of Japan Society secretary
Association Membership(s) (5)：
歯科基礎医学会 ,  The antibody society of Japan ,  The Japanese Biochemical Society ,  Shikoku Society of Dental Research ,  The Molecular Biology Society of Japan
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