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J-GLOBAL ID：201501012232153614 Update date: Apr. 11, 2025

Koseki Hirokazu

コセキヒロカズ | Koseki Hirokazu

Affiliation and department：
Job title：助教
Homepage URL (1)： https://www.researchgate.net/profile/Hirokazu-Koseki

Research field (1)： Neurosurgery

Research keywords (4)： brain tumor , awake surgery , 神経内視鏡 , 脳動脈瘤

Research theme for competitive and other funds (4)：

2023 - 2026 口腔内細菌叢のメタゲノム解析に基づく脳動脈瘤病態形成機序の解明
2018 - 2022 Evaluation of the relationship between chronic psychological stress and intracranial aneurysm formation / rupture
2016 - 2019 Contribution of T cell function to the pathogenesis of intracranial aneurysms.
2015 - 2018 Identification of susceptible genes by genome-wide genetic analysis in patients with familial aneurysms

Papers (39)：

清水寛平, 片岡大治, 今井宏彦, 山本悠斗, 山田智裕, 宮田悠, 小関宏和, 安部倉友, 岡美栄子, 九社前美香, et al. 炎症依存的な嚢状動脈瘤増大を制御する因子としての血行力学的負荷ラット動脈瘤モデルにおける検証. 天理医学紀要. 2023. 26. 1-2. 62-64
小関宏和, 府賀道康, 佐野透, 園田章太, 郭樟吾, 小菊実, 小林伸行, 近藤一博, 長山剛太, 加藤直樹, et al. 脳動脈瘤患者における新規ストレス耐性マーカー"SITH-1"の測定意義. 脳血管内治療. 2023. 8. Suppl. S866-S866
Akihiro Okada, Hirokazu Koseki, Isao Ono, Tomomichi Kayahara, Hiroki Kurita, Susumu Miyamoto, Hiroharu Kataoka, Tomohiro Aoki. Identification of The Unique Subtype of Macrophages in Aneurysm Lesions at the Growth Phase. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association. 2022. 31. 12. 106848-106848
Soichiro Fujimura, Kazutoshi Tanaka, Hiroyuki Takao, Takuma Okudaira, Hirokazu Koseki, Akiko Hasebe, Takashi Suzuki, Yuya Uchiyama, Toshihiro Ishibashi, Katharina Otani, et al. Computational fluid dynamic analysis of the initiation of cerebral aneurysms. Journal of neurosurgery. 2021. 1-9
Hirokazu Koseki, Yuichi Murayama. [History and Recent Development of Basic Research Using an Experimental Intracranial Aneurysm Model]. No shinkei geka. Neurological surgery. 2021. 49. 4. 888-897

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MISC (25)：

Tomoki Kasai, Hirokazu Koseki, Hiroyuki Takao, Soichiro Fujimura, Naoki Kato, Issei Kan, Shota Sunami, Kazuya Yuzawa, Hayato Uchikawa, Toshihiro Ishibashi, et al. Investigation of Aneurysmal Initiation Factor with Experimental Animal Model by Computational Fluid Dynamics Analysis. Stroke: Vascular and Interventional Neurology. 2023. 3. S1. e12488
小関宏和, 府賀道康, 府賀道康, 佐野透, 園田章太, 郭樟吾, 小菊実, 小林伸行, 近藤一博, 長山剛太, et al. 脳動脈瘤患者における新規ストレス耐性マーカー“SITH-1”の測定意義. 脳血管内治療(Web). 2023. 8. Supplement
Akasaki Y, Suzuki T, Takei J, Tanaka T, Mori R, Koseki H, Yamamoto Y, Teshigawara A, Kamata Y, Yanagisawa T, et al. Pros and cons of surgical intervention for diffuse midline glioma aimed at dendritic cell immunotherapy. Neuro-Oncology Advances. 2022. 4. 3. iii12
葛西智基, 小関宏和, 高尾洋之, 藤村宗一郎, 加藤直樹, 菅一成, 石橋敏寛, 福留功二, 山本誠, 村山雄一. 実験的動物モデルに対するCFD解析と血管組織の観察による動脈瘤発生因子の特定に関する研究. 脳血管内治療. 2022. 7. Suppl. S113-S113
Tomoto Kyoichi, Yamamoto Yohei, Tanaka Toshihide, Suzuki Tomoya, Teshigawara Akihiko, Takei Jun, Koseki Hirokazu, Mori Ryosuke, Akasaki Yasuharu, Murayama Yuichi. CLINICAL BENEFIT OF ADD-ON BEVACIZUMAB FOR NEWLY DIAGNOSED GLIOBLASTOMA IN ELDERLY PATIENTS WITH UNRESECTABLE AND POOR PERFORMANCE STATUS. Neuro-Oncology Advances. 2022. 4. 3. iii12

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Patents (1)：

Head pin

Books (1)：

脳血管内治療学 : 完全版 : 病態・治療法の本質的理解と臨床・研究発展のために
メディカ出版 2018 ISBN:9784840464895

Lectures and oral presentations (44)：

A case of supratentorial ependymoma with rapid recurrence and intrathecal dissemination
(2024)
Elucidation of the mechanism of intracranial aneurysm initiation using computational fluid dynamics analyses
(2024)
Significance of remote EEG diagnosis system using communication application in emergency room
(2023)
Significance of a novel stress tolerance marker, SITH-1, in patients with intracranial aneurysms
(2023)
A case of cloudy cerebrospinal fluid during endoscopic hematoma removal
(2023)

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Education (1)：

2001 - 2008 University of Yamanashi Faculty of Medicine School of Medicine

Professional career (1)：

博士(医学) (東京女子医科大学)

Work history (5)：

2019/07 - 現在 Jikei University
2015/04 - 2019/06 Tokyo Women's Medical University Medical Center East
2017/04 - 2018/03 National Cerebral and Cardiovascular Center, Research Institute Department of molecular pharmacology Research fellowship
2015/04 - 2017/03 Kyoto University Graduate School of Medicine Innovation Center for Immunoregulation Technologies and Drugs Research fellowship
2010/04 - 2015/03 Tokyo Women's Medical University Medical Center East

Association Membership(s) (9)：

Japanese Society for Neuroendovascular Therapy , Sigma Xi, The Scientific Research Society , 日本分子脳神経外科学会 , 日本整容脳神経外科学会 , 日本間脳下垂体腫瘍学会 , 日本神経内視鏡学会 , 日本脳卒中の外科学会 , 日本脳卒中学会 , 日本脳神経外科学会

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