Takada Kensuke

タカダケンスケ | Takada Kensuke

Affiliation and department：
Job title： Specially appointed associate professor
Homepage URL (1)： https://www.ivred.hokudai.ac.jp

Research field (1)： Immunology

Research keywords (10)： vaccine , Immunological memory , 獲得免疫 , T細胞 , 免疫学 , 胸腺 , ストローマ細胞 , 正の選択 , リンパ節 , 二次リンパ組織

Research theme for competitive and other funds (33)：

2021 - 2024 核内受容体REV-ERBによる免疫記憶制御の分子基盤の解明とワクチン療法への応用
2020 - 2023 Mechanism for the roles of cholesterol-binding membrane protein TSPO2 in terminal erythroid differentiation
2020 - 2022 Molecular mechanisms of immune memory maintenance corresponding to the risk of reinfection
2017 - 2021 核内受容体間を介した免疫記憶形成機構の解明とワクチン療法への応用
2016 - 2020 Positive selection of T cells in the thymic cortex

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Papers (35)：

Shangyi Wang, Mina Kozai, Masaya Hiraishi, Md. Zahir Uddin Rubel, Osamu Ichii, Mutsumi Inaba, Kazuhiro Matsuo, Kensuke Takada. Roles of tumor necrosis factor-like ligand 1A in γδT-cell activation and psoriasis pathogenesis. Frontiers in Immunology. 2024. 15. 1340467
Yuqi Chen, Kosuke Miyazono, Yayoi Otsuka, Mariko Kanamori, Aozora Yamashita, Nobuto Arashiki, Takehisa Matsumoto, Kensuke Takada, Kota Sato, Narla Mohandas, et al. Membrane skeleton hyperstability due to a novel alternatively spliced 4.1R can account for ellipsoidal camelid red cells with decreased deformability. Journal of Biological Chemistry. 2023. 102877-102877
Shangyi Wang, Mina Kozai, Hironobu Mita, Zimeng Cai, Md Abdul Masum, Osamu Ichii, Kensuke Takada, Mutsumi Inaba. REV-ERB agonist suppresses IL-17 production in γδT cells and improves psoriatic dermatitis in a mouse model. Biomedicine & pharmacotherapy. 2021. 144. 112283-112283
Izumi Ohigashi, Melina Frantzeskakis, Alison Jacques, Sayumi Fujimori, Aya Ushio, Fusano Yamashita, Naozumi Ishimaru, Da Yin, Margaret Cam, Michael C Kelly, et al. The thymoproteasome hardwires the TCR repertoire of CD8+ T cells in the cortex independent of negative selection. The Journal of Experimental Medicine. 2021. 218. 4
Zimeng Cai, Taishin Ishibashi, Mina Kozai, Hironobu Mita, Shangyi Wang, Kensuke Takada, Mutsumi Inaba. ROR agonist hampers the proliferation and survival of postactivated CD8 + T cells through the downregulation of cholesterol synthesis-related genes. Immunology & Cell Biology. 2021. 99. 3. 288-298

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MISC (8)：

王上一, 香西美奈, RUBEL Md. Zahir Uddin, 平石真也, 市居修, 高田健介, 稲葉睦. Roles of an inflammatory cytokine TL1A in gdT cell activation and psoriasis pathogenesis. 日本獣医学会学術集会講演要旨集. 2023. 166th
TAKADA KENSUKE, TAKIGUCHI MITSUYOSHI, INABA MUTSUMI. シェーグレン症候群モデルマウス・IQI/Jicにおける自己抗原の同定. 日本獣医学会学術集会講演要旨集. 2004. 138th. 160-160
TAKADA KENSUKE, TAKIGUCHI MITSUYOSHI, INABA MUTSUMI. シェーグレン症候群モデルマウス・IQI/Jicにおける多発性自己免疫病変の組織学的解析および自己抗原の同定. 日本獣医学会学術集会講演要旨集. 2003. 136th. 218-218
TAKIGUCHI MITSUYOSHI, TAKADA KENSUKE. 副腎性性ホルモン機能こう進症とポメラニアンの脱毛症X. 日本獣医学会学術集会講演要旨集. 2003. 136th. 54-54
TAKADA Kensuke, KITAMURA Hiroshi, TAKIGUCHI Mitsuyoshi, SAITO Masayuki, HASHIMOTO Akira, INABA Mutsumi. Cloning and polymorphic analysis of canine 21-hydroxyrase gene : a candidate gene for alopecia X in dogs. Veterinary biochemistry. 2003. 40. 1. 21-27

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Lectures and oral presentations (8)：

Nuclear receptor RORalpha regulates bystander activation of memory T cells
(2022)
REV-ERB agonist suppresses IL-17 production in gdT cells and improves psoriatic dermatitis in a mouse model
(2022)
Nuclear receptor RORalpha regulates bystander activation of memory T cells
(2021)
Roles of nuclear receptors REV-ERBs in effector and memory T cell differentiation
(2020)
核内受容体間の競合がCD8+ T細胞の活性化と記憶形成に及ぼす影響
(2019)

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Education (2)：

2001 - 2005 Hokkaido University Graduate School of Veterinary Medicine
1995 - 2001 Hokkaido University School of Veterinary Medicine

Professional career (1)：

博士(獣医学) (北海道大学)

Work history (6)：

2023/04 - 現在 Hokkaido University Institute for Vaccine Research and Development Specially appointed associate professor
2017/04 - 2023/03 Hokkaido University Faculty of Veterinary Medicine Associate professor
2016/10 - 2017/03 Hokkaido University Graduate School of Veterinary Medicine Associate professor
2015/08 - 2016/09 The University of Tokushima
2010/09 - 2014/07 The University of Tokushima

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Awards (2)：

2015/11 - 徳島大学学長表彰
2015/11 - 日本免疫学会研究奨励賞

Association Membership(s) (2)：

日本獣医学会 , JAPANESE SOCIETY FOR IMMUNOLOGY

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