Research field (7):
Nutrition and health science
, Hygiene and public health (non-laboratory)
, Hygiene and public health (laboratory)
, Healthcare management, medical sociology
, Metabolism and endocrinology
, Pathobiochemistry
, Other
Research theme for competitive and other funds (20):
2025 - 2028 Uncovering the multifaceted effects of preventive action on cardiovascular disease and molecular mechanisms: Multidisciplinary epidemiological study
2024 - 2027 Verification of the relationship between DNA methylation levels of various leukocyte genes and cardiovascular diseases through a longitudinal study
2022 - 2027 Worsening of chronic condition during COVID-19 pandemic and association of occupational factors with the incidence of cardiovascular diseases in workers with chronic condition
2022 - 2027 Worsening of chronic condition during COVID-19 pandemic and association of occupational factors with the incidence of cardiovascular diseases in workers with chronic condition
2023 - 2026 Construction of integrated risk model for gastrointestinal and lung cancers based on genomic information and blood biomarkers
2020 - 2023 Longitudinal study on the fluctuation factors of DNA methylation of metabolic and inflammatory genes in leukocytes
2019 - 2022 Research on RNA as the early diagnostic marker of gastrointestinal and lung cancers using preserved samples of cohort studies
2018 - 2022 A life course worksite-based cohort study of frailty and participation from adulthood until after retirement
2018 - 2021 Effects of Fructose Consumption on the Central Nervous System of the Next Generation
2017 - 2020 Longitudinal study on the relationship between the DNA methylation status of metabolism-related genes and the development of lifestyle-related diseases
2017 - 2020 Possibility of HDL-miRNA as a biomarker for arteriosclerosis development and progression
2017 - 2020 Development of the atherosclerosis biomarker for preemptive medicine
2014 - 2018 Spatial and genetic epidemiological study on the pathogenesis of obesity and diabetes
2014 - 2017 Associtation circulating miRNAs and lifestyle : aiming at application to clinical examination
2014 - 2017 Analysis of the methylation status of leukocytes DNA stored in a longitudial cohort study
2014 - 2017 A nested case-control study in the JACC Study to investigate biomarkers of premature death
2014 - 2017 Effect of maternal excess fructose consumption on the offspring
2011 - 2012 Development of novel cell detection system targeting microRNAexpression
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Papers (119):
Yoshiki Tsuboi, Hiroya Yamada, Ryosuke Fujii, Mirai Yamazaki, Eiji Munetsuna, Yoshitaka Ando, Koji Ohashi, Hiroaki Ishikawa, Hiroshi Okumiyama, Masaya Nakae, et al. High circulating microRNA-197 levels are associated with an increased risk of incident stroke among elderly survivors of the Great East Japan Earthquake. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 2024. 29. 6. 368-375
Mirai Yamazaki, Hiroya Yamada, Eiji Munetsuna, Yoshitaka Ando, Genki Mizuno, Atsushi Teshigawara, Hayato Ichikawa, Yuki Nouchi, Itsuki Kageyama, Takuya Wakasugi, et al. Approaches to nutritional research using organoids; fructose treatment induces epigenetic changes in liver organoids. The Journal of nutritional biochemistry. 2024. 131. 109671-109671
Keisuke Maeda, Ryosuke Fujii, Hiroya Yamada, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Genki Mizuno, Hiroaki Ishikawa, Koji Ohashi, Yoshiki Tsuboi, et al. Association between DNA methylation levels of thioredoxin-interacting protein (TXNIP) and changes in glycemic traits: a longitudinal population-based study. Endocrine journal. 2024
Yoshitaka Ando, Eiji Munetsuna, Hiroya Yamada, Miyuki Ikeya, Atsushi Teshigawara, Itsuki Kageyama, Yuki Nouchi, Takuya Wakasugi, Mirai Yamazaki, Genki Mizuno, et al. Impact of maternal fructose intake on liver stem/progenitor cells in offspring: Insights into developmental origins of health and disease. Life sciences. 2024. 336. 122315-122315
Genki Mizuno, Hiroya Yamada, Yoshiki Tsuboi, Eiji Munetsuna, Mirai Yamazaki, Yoshitaka Ando, Itsuki Kageyama, Yuki Nouchi, Atsushi Teshigawara, Yuji Hattori, et al. Low mitochondrial DNA copy number in peripheral blood mononuclear cells is associated with future mortality risk: a long-term follow-up study from Japan. The journal of nutrition, health & aging. 2024. 28. 1. 100013-100013