Research field (1):
Pharmaceuticals - health and biochemistry
Research keywords (1):
Immunology, Immunotoxicology
Research theme for competitive and other funds (18):
2022 - 2025 環境性肺疾患における炭素微粒子受容体の病理的役割
2022 - 2024 TrogocytosisによるMHCドレス化分子機構の解明
2019 - 2022 Pathological role of scavenger receptor family molecules in lung diseases associated with environmental particles
2017 - 2021 マクロファージによる粒子状物質パターン認識機構の解明
2017 - 2020 Design of membrane permeated nanocarriers with avoiding drug-resistant transporters
2016 - 2019 Inflammatory responses to crystals and nanoparticles
2016 - 2018 Molecular mechanism of MHC trogocytosis
2013 - 2016 Pathogenesis of inflammation or allergy in dental metal material
2013 - 2015 Trogocytosisによる細胞分化機構の解明
2012 - 2015 Macrophage inflammatory responses to amorphous silica particles
2010 - 2012 Imminological analysis of inflammation by dental materials
2010 - 2011 Phagocytosis of apoptotic cells and cross-presentation by DC
2008 - 2010 Development of strategy to treat allergic diseases via targeting surface molecules on lymphocytes and intracellular signaling molecules
2008 - 2010 Development of novel cancer therapy by combination of immune activation with tumor apoptosis induction
2008 - 2009 免疫による癌拒絶局所での分子機構の解析
2007 - 2008 Identification and characterization of novel macrophage receptors for bacteria
2006 - 2007 Functional analysis of costimulatory molecules for autoimmune diseases
2000 - 2002 新規アポトーシス誘導分子の同定と解析
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Papers (49):
Arisa Hori, Saori Toyoura, Miyu Fujiwara, Ren Taniguchi, Yasutaka Kano, Tomoyoshi Yamano, Rikinari Hanayama, Masafumi Nakayama. MHC class I-dressing is mediated via phosphatidylserine recognition and is enhanced by polyI:C. iScience. 2024. 27. 5. 109704-109704
Miki Kuroiwa, Shin-Ichiro Yamaguchi, Yoshinobu Kato, Arisa Hori, Saori Toyoura, Mai Nakahara, Nobuyuki Morimoto, Masafumi Nakayama. Tim4, a macrophage receptor for apoptotic cells, binds polystyrene microplastics via aromatic-aromatic interactions. The Science of the total environment. 2023. 875. 162586-162586
Masafumi Nakayama, Arisa Hori, Saori Toyoura, Shin-Ichiro Yamaguchi. Shaping of T Cell Functions by Trogocytosis. Cells. 2021. 10. 5
Satoshi Omori, Misato Tsugita, Yasuto Hoshikawa, Masanobu Morita, Fumiya Ito, Shin-Ichiro Yamaguchi, Qilin Xie, Osamu Noyori, Tomoya Yamaguchi, Ayato Takada, et al. Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation. Cell reports. 2021. 34. 6. 108734-108734
NAKAYAMA Masafumi. Macrophage recognition of inorganic nanoparticles and crystals. Annual Meeting of the Japanese Society of Toxicology. 2019. 46.1. S14-1
The Pharmaceutical Society of Japan
, The Japanese Society for Cell Death Research
, The Japanese Society of Toxicology
, The Japanese Society of Immunotoxicology
, The Japanese Society for Immunology