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J-GLOBAL ID:201501038814340204   Update date: Sep. 11, 2024

Akari Hagiwara

ハギワラ アカリ | Akari Hagiwara
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Affiliation and department:
Job title: Associate Professor
Homepage URL  (1): https://www.rs.tus.ac.jp/ahagiwar/
Research field  (4): Basic brain sciences ,  Neuroanatomy and physiology ,  Morphology, anatomy ,  Neuroscience - general
Research keywords  (2): Brain function, Neural network, Synapse, Electron microscopy ,  Neuroscience
Research theme for competitive and other funds  (11):
  • 2022 - 2025 アクティブゾーン分子複合体の動態制御機構と多様性の理解
  • 2023 - 2024 育児経験によって変化する養育行動の神経プロファイリング解析
  • 2020 - 2023 シナプスタンパク質CAST/ELKSの欠損による網膜変性の作用機序解析
  • 2019 - 2022 Molecular and structural basis and modification mechanisms of the active zones regulating synaptic transmission efficiency
  • 2021 - 2022 うつ病等の神経疾患に関与する神経機構とシナプス伝達の解析
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Papers (25):
  • Akari Hagiwara, Ayako Mizutani, Saki Kawamura, Manabu Abe, Yamato Hida, Kenji Sakimura, Toshihisa Ohtsuka. Critical Role of the Presynaptic Protein CAST in Maintaining the Photoreceptor Ribbon Synapse Triad. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. 2023. 24. 8. 7251
  • Shun Hamada, Masashi Nagase, Tomohiko Yoshizawa, Akari Hagiwara, Yoshikazu Isomura, Ayako M. Watabe, Toshihisa Ohtsuka. An engineered channelrhodopsin optimized for axon terminal activation and circuit mapping. Communications Biology. 2021. 4. 1
  • Misato Yasumura, Akari Hagiwara, Yamato Hida, Toshihisa Ohtsuka. Planar cell polarity protein Vangl2 and its interacting protein Ap2m1 regulate dendritic branching in cortical neurons. GENES TO CELLS. 2021
  • Akari Hagiwara, Naoko Sugiyama, Toshihisa Ohtsuka. Impaired experience-dependent maternal care in presynaptic active zone protein CAST-deficient dams. Scientific Reports. 2020. 10. 5238
  • Akari Hagiwara, Shun Hamada, Yamato Hida, Toshihisa Ohtsuka. Double deletion of the active zone proteins CAST/ELKS in the mouse forebrain causes high mortality of newborn pups. Molecular Brain. 2020. 13. 13
more...
MISC (1):
  • Natsumi Ageta-Ishihara, Akari Hagiwara, Hiroyuki Kurita, Takao Morita, Takashi Tomonaga, Yugo Fukazawa, Ryuichi Shigemoto, Makoto Kinoshita. Exploring functions of the septin cytoskeleton in the formation and remodeling of neuroglial network. Neuroscience Research. 2010. 68. E124-E124
Books (1):
  • SDS-Digested Freeze-Fracture Reprica Labeling (SDS-FRL)” in Handbook of Cryo-Preparation Methods for Electron Microscopy
    CRC Press 2008 ISBN:9780849372278
Lectures and oral presentations  (36):
  • Depletion of presynaptic active zone protein CAST in mice cause low tolerance for stress and depressive-like behaviors.
    (Neuro2024(第47回日本神経科学大会) 2024)
  • Depletion of LKB1 in cerebellar granule cells causesparallel fiber remodeling implying contribution to motorcoordination
    (Neuro2024(第47回日本神経科学大会) 2024)
  • Dendritic branching of Horizontal cells organizes photoreceptor ribbon synapse distribution and formation in the cone terminal
    (Neuro2024(第47回日本神経科学大会) 2024)
  • 最初期遺伝子c-Fosを利用した神経活動依存的な形態学的マッピング法の検証
    (日本顕微鏡学会 第80回学術講演会 2024)
  • 小脳顆粒細胞LKB1欠損マウスのシナプスリモデリングに関する形態学的解析
    (日本顕微鏡学会 第80回学術講演会 2024)
more...
Education (5):
  • 2001 - 2004 The Graduate University for Advanced Studies 生命科学研究科
  • - 2004 The Graduate University for Advanced Studies School of life science Department of Physiological Sciences
  • 1999 - 2001 Keio University 理工学研究科
  • 1995 - 1999 Keio University Applied Chemistry
  • - 1999 Keio University Faculty of Science and Engineering
Professional career (1):
  • Ph D (The Graduate University for Advanced Studies)
Work history (7):
  • 2021/04 - 現在 Tokyo University of Science Faculty of Science and Technology Associate professor
  • 2019/04/01 - University of Yamanashi Department of Biology Associate professor
  • 2015/03/01 - University of Yamanashi Department of Biology Senior assistant professor
  • 2010/09/01 - University of Yamanashi Department of Biology Assistant professor
  • 2007/04/01 - Harvard University Dept of Molecular and Cellular Biology Postdoc
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Awards (4):
  • 2023/07/06 - 16th Shiseido Female Researcher Science Grant
  • 2022/03/07 - ライフサイエンス振興財団研究助成
  • 2021/07/01 - 武田科学振興財団 医学系研究助成(精神・神経・脳領域)
  • 2015/11 - 秋山勝彦グローバル人材育成奨学支援金事業
Association Membership(s) (3):
日本顕微鏡学会 ,  The Japan Neuroscience Society ,  Society for Neuroscience
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